N/A N=37 Ventriculostomies in SAH: ICP Open or Not?
Subarachnoid Hemorrhage
Primary: Cerebral Artery Vasospasm — 16; 7 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=57 Treating Brain Swelling in Pediatric Cerebral Malaria
Malaria, Cerebral
Primary: Number of Participants Who Died — 5; 5; 5 Participants
N/A N=38 A Randomized Cross-over Study for Normal Pressure Hydrocephalus
Normal Pressure Hydrocephalus
Primary: Tinetti Score on Open Shunt vs. Closed Shunt — 24.50; 26.50 score on a scale
Phase 3 N=7 PET Imaging of Brain Amyloid in Normal Pressure Hydrocephalus
Normal Pressure Hydrocephalus
Primary: Quantitative Estimates of Brain Uptake [18F]Flutemetamol and the Quantitative Immunohistochemical (IHC) Estimates of Amyloid Levels in Biopsy Samples Previously…
N/A N=12 MRI for Non-invasive Evaluation of Brain Stress
Craniosynostosis
Primary: Blood Flow and Perfusion — 26.8 ml/min/100g — p=0.004
N/A N=433 A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of Hydrocephalus
Hydrocephalus
Primary: Number of Subjects With Shunt Infections — 14 participants
Phase 2 N=12 Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease
Sickle Cell Disease · Stroke
Primary: Number of Randomized Participants With Central Nervous System Complications — 1; 4 Participants — p=0.2914
N/A N=5 Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters
Hydrocephaly
Primary: To Demonstrate That the Flusher Can be Primed, Connected, and Activated in a Sterile Clinical Setting Per the Instructions for Use by the Treating Investigator . — 4; 4…
N/A N=5 Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial Hypotension
Intracranial Hypotension
Primary: Intracranial Pressure Measurements Estimated by the MRICP Technique. — 6.5 cm H20
N/A N=10 Brain Characteristics Noted Prior to and Following Treatment
Nonsynostotic Plagiocephaly
Primary: Number of Participants With Qualitatively Determined Normalization of White Matter Pathways — 2 Participants
N/A N=23 Cranial Cup Use for Correction of Head Shape Deformities
Dolichocephaly
Primary: Feasibility and Safety — 7; 1 count
N/A N=44 Assessment of CSF Shunt Flow With Thermal Measurements A
Hydrocephalus
Primary: Study Device Sensitivity — 88 percent
N/A N=141 Assessment of CSF Shunt Flow With Thermal Measurements B
Hydrocephalus
Primary: Study Device Sensitivity — 88.9 percent of ground truth positive cases
N/A N=20 Cerebral Edema in Pediatric Diabetic Ketoacidosis
Diabetic Ketoacidosis
Primary: Cerebral Edema Measured by MR Imaging (Apparent Diffusion Coefficient) — 36; 48 mm^2/sec
N/A N=117 External Ventricular Drainage Post-Market Clinical Follow-up Registry
Cerebrospinal; Disorder
Primary: Anticipated Drainage of Cerebrospinal Fluid (CSF) — 116 Participants
N/A N=130 A Study on the Safety of Hakim Programmable Shunt System
Hydrocephalus
Primary: Number of Participants With Non-infection Within One Year — 5 Participants
N/A N=18 A Placebo-Controlled Effectiveness in INPH Shunting (PENS) Trial
Idiopathic Normal Pressure Hydrocephalus (INPH)
Primary: Change in Gait Velocity — 0.28; 0.04 meters per second — p=0.071
Phase 3 N=500 High-dose Erythropoietin for Asphyxia and Encephalopathy
Neonatal Encephalopathy · Birth Asphyxia
Primary: Number of Participants With Death or Neurodevelopmental Impairment — 126; 110 Participants
N/A N=25 Catheter Placement for Hepatic Hydrothorax
Pleural Effusion
Primary: Feasibility of Using Indwelling Tunneled Pleural Catheters for the Management of Hepatic Hydrothorax — 25 Participants
Phase 3 N=12 Hydrocortisone for Term Hypotension
Infant, Newborn, Diseases · Cardiovascular Insufficiency
Primary: Death — 6; 6; 0; 0 Participants