N/A N=54 Effectiveness of Pressure Garment Therapy After Burns
Hypertrophic Scarring After Burn Injury
Primary: Pressure Under Compression Garment — 25; 6.4 mm Hg
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=29 Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
Burn Scars
Primary: Scar Pigmentation, Baseline vs 15-months — 50.93; 49.59 units on a scale
N/A N=18 Fractional Ablative Laser Treatment for Skin Grafts
Burn Scar · Skin Graft Scar
Primary: Contracture of Scar Surface Area (Percentage of Original Area) — 97; 97 percentage
Phase 4 N=20 Comparison of Wound Bed Establishment in Facial Burns
Burns
Primary: Time to Wound Epithelialization — 37.4; 37.6 days — p=.0853
Phase 2 N=60 Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention
Fibrosis · Skin Scarring · Skin Wound
Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline
Phase 3 N=244 Assessment of Mechanisms of Improved Wound Healing
Burns
Primary: Decrease Hypermetabolism as Measured by Stable Isotope Infusion Study
N/A N=30 Post Excision/Mohs Scar Laser Resurfacing
Skin Cancer
Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale
N/A N=146 Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Scar · Skin Scarring · Skin Cancer
Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale
Phase 2 N=42 Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)
Post-operative Excessive Scarring
Primary: Modified Manchester Scar Scale (MMSS) Score — 8; 11.5 score on a scale
N/A N=20 Treatment of Post-Surgical Scars With Traditional Ablative Er:YAG Versus Fractional Ablative Er:YAG
Post-Surgical Scars
Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019
Phase 2 N=100 Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
Reduction of Hypertrophic Skin Scarring
Primary: Physician Global Assessment Using Physician Overall Opinion Question of Patient and Observer Scar Assessment Scale (POSAS) — 4.00; 4.68; 4.61; 4.86 units on scale…
N/A N=36 Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
Surgical Incision
Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale
Phase 1 N=30 StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
Skin Wound · Burns · Trauma-related Wound
Primary: Number of Participants With Wound Closure of the Treatment Sites at Three Months — 29; 29 Participants
N/A N=30 ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Number of Participants With Confirmed Treatment Area Closure of RECELL-treated Wounds Compared to Control (Non-inferiority) — 24; 22; 2; 4 Participants
N/A N=44 Platelet-Rich Plasma (PRP) in Reconstructive Surgery on Children With Retractable Burn Sequelae on Extremities
Burns
Primary: Median Time Between Surgery Date and Start Date Compression. — 17; 19 day — p=>0.1574
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
Phase 2 N=12 Study of EB-001 in Facial Scar Reduction
Mohs Surgery
Primary: Assessment of Visual Analog Scale (VAS) Change (Values From 0 (Worst) to 10 (Best)) — 0; 50 Percentage reporting improvement
N/A N=51 Treatment of Surgical Scars Following Breast Augmentation, Abdominoplasty or Face Lift
Surgical Scar · Breast Augmentation · Abdominoplasty
Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…
Phase 4 N=28 Effect of Collagenase on Healing and Scarring
Scarring · Impaired Wound Healing
Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05
Phase 3 N=34 Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound
Deep Partial Thickness Burn
Primary: Time of Healing by Monitoring Duration (Days) at the Beginning of Treatment and the Day of Completely Epithelialization (Complete Epithelialization Means no Open Wound…
Phase 2 N=22 Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Scars
Primary: Patient and Observer Scar Assessment Scale (POSAS) - PI Assessment — 4.4; 4.5 score on a scale
N/A N=10 An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Wound Healing
Primary: Number of Participants With Wound Healing — 10 participants
N/A N=10 Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring
Acne Scars - Mixed Atrophic and Hypertrophic
Primary: Mean Change From Baseline in Erythema — -1.687; 5.730 units on a scale
N/A N=67 A Study of a Novel Silicone Dressing to Minimize Scar Formation
Hypertrophic
Primary: Visual Analogue Scale (VAS) — 2.90; 3.29 score on a scale
Phase 2 N=5 Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery
Scar Formation
Primary: Photography- Independent Scar Assessment Panel
Phase 3 N=71 StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
Burn, Thermal
Primary: Percent Area of Treatment Sites Requiring Autografting by Month 3 — 4.33; 102.10 percentage of treatment sites — p=<0.0001
Phase 4 N=19 Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
Keloid Scar
Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale
N/A N=45 A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Burns · Wound Healing
Primary: Number of Subjects Healed at Day 14. — 35 participants
N/A N=51 Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
Cicatrix · Carbon Dioxide Laser
Primary: Change in Vectra Measured Length V1 (Month 0)-V2 (Month 3) for Original Group; Visit 3 (Month 6) to Visit 4 (Month 9) for Crossover Group — 0.10; 0.03 mm
N/A N=15 Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
Burns
Primary: Evaluate the Experience of Using Mepilex Border Ag ( a Silver Dressing) in Normal Clinical Practice — 9 burns healed