N/A N=36 Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
Surgical Incision
Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=100 Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
Reduction of Hypertrophic Skin Scarring
Primary: Physician Global Assessment Using Physician Overall Opinion Question of Patient and Observer Scar Assessment Scale (POSAS) — 4.00; 4.68; 4.61; 4.86 units on scale…
N/A N=51 Treatment of Surgical Scars Following Breast Augmentation, Abdominoplasty or Face Lift
Surgical Scar · Breast Augmentation · Abdominoplasty
Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…
N/A N=30 Post Excision/Mohs Scar Laser Resurfacing
Skin Cancer
Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale
N/A N=146 Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Scar · Skin Scarring · Skin Cancer
Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale
N/A N=20 Treatment of Post-Surgical Scars With Traditional Ablative Er:YAG Versus Fractional Ablative Er:YAG
Post-Surgical Scars
Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019
Phase 2 N=42 Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)
Post-operative Excessive Scarring
Primary: Modified Manchester Scar Scale (MMSS) Score — 8; 11.5 score on a scale
Phase 2 N=60 Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention
Fibrosis · Skin Scarring · Skin Wound
Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline
Phase 2 N=14 Safety and Efficacy of EXC 001 in Subjects Who Have Participated in Prior Studies of EXC 001
Reduction in Severity of Skin Scarring
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 8; 0 Participants
Phase 2 N=22 Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Scars
Primary: Patient and Observer Scar Assessment Scale (POSAS) - PI Assessment — 4.4; 4.5 score on a scale
N/A N=264 Silicone Gel for Postsurgical Scars of the Eyelid
Scarring Due to Treatment
Primary: Post-operative Scarring - Erythema — 1.67; 1.70; 1.50; 1.65 score on a scale — p=0.48
N/A N=12 Clinical Evaluation of the GLYDe Dressing for Post-surgical Incision Care
Post Surgical Incisions From Abdominoplasty Procedures
Primary: Scar Evaluation at End of Treatment Period Comparing Treated to Standard of Care (Control) — 18.64; 50.52 score on a scale
Phase 2 N=5 Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery
Scar Formation
Primary: Photography- Independent Scar Assessment Panel
N/A N=40 Clinical Trial to Evaluate the Safety and Efficacy of Scarclinic™ Thin in Surgical Scars
Hypertrophic Surgical Scar
Primary: Change From Baseline in Vancouver Scar Scale Score(VSS) at 3 Months — -3.80; -2.61 units on a scale
N/A N=67 A Study of a Novel Silicone Dressing to Minimize Scar Formation
Hypertrophic
Primary: Visual Analogue Scale (VAS) — 2.90; 3.29 score on a scale
Phase 4 N=19 Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid
Keloid Scar
Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale
N/A N=51 Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
Cicatrix · Carbon Dioxide Laser
Primary: Change in Vectra Measured Length V1 (Month 0)-V2 (Month 3) for Original Group; Visit 3 (Month 6) to Visit 4 (Month 9) for Crossover Group — 0.10; 0.03 mm
N/A N=74 Randomized Controlled Trial of Subcuticular Skin Closure Versus Steri-strip S Closure
Breast Hypertrophy · Abdominal Elastosis · Breast Reconstruction
Primary: Scar Quality at 6 Months Postoperative — 3.8; 2.6 units on a scale
N/A N=60 Timing of Suture Removal to Reduce Scarring in Skin Surgery
Suture Related Complication
Primary: The Measured Difference in POSAS and VAS Scores Between 7-day and 10-day Groups — 12.9; 16.1; 19.5; 20.3 score on a scale
Phase 4 N=28 Effect of Collagenase on Healing and Scarring
Scarring · Impaired Wound Healing
Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05
Phase 2 N=12 Study of EB-001 in Facial Scar Reduction
Mohs Surgery
Primary: Assessment of Visual Analog Scale (VAS) Change (Values From 0 (Worst) to 10 (Best)) — 0; 50 Percentage reporting improvement
N/A N=24 Negative Pressure Wound Therapy-PICO: Cosmesis in Repeat C-Sections
Hypertrophic Skin Condition of Anterior Abdomen
Primary: Subjective Cosmetic Result — 13; 26.5 units on a scale
Phase 4 N=30 A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars
Keloid · Hypertrophic Scar · Cicatrix, Hypertrophic
Primary: Change in Lesion Volume — 40; 42; 32 Percent Change
Phase 2 N=30 Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
Scar Prevention
Primary: Part B: Expert Panel Scar Assessment Score — -3.16; 0.18; 1.45; 2.91 millimeters
N/A N=54 Effectiveness of Pressure Garment Therapy After Burns
Hypertrophic Scarring After Burn Injury
Primary: Pressure Under Compression Garment — 25; 6.4 mm Hg
Phase 2 N=41 Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
Scar Prevention
Primary: Expert Panel Scar Assessment Score at Week 12: Part B — 37.8; 42.1 millimeter — p=0.168
Phase 2 N=25 Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
Scar Prevention
Primary: Expert Panel Scar Assessment Score at Week 12 — 36.6; 51.4 millimeter — p=<0.001
N/A N=34 SERI® Surgical Scaffold for Soft Tissue Support in Revision Augmentation Surgery
Subjects Requiring Revision Breast Augmentation Surgery
Primary: Reoperation Rate (Per Implanted Breast) for the Presenting Condition at 12 Months. — 0; 0 Implanted breasts
N/A N=20 Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars
Scar · Surgical Scar · Cicatrix
Primary: Improvement in Surgical Scar of Treatment (532nm KTP Laser) and Active Control (595nm PDL) Treatment Arms. — 2.0; 1.5 score on a scale
Phase 2 N=68 Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery
Reduction in Hypertrophic Skin Scarring
Primary: Physician Observer Scar Assessment Score at Week 24 — 0.0; -0.5; 0.8; -0.3 units on a scale — p=1.000