N/A N=958 Gestational Diabetes Mellitus Trial (GDM)
Diabetes, Gestational
Primary: Number of Participants With Composite Neonatal Morbidity — 149; 163; 62; 55 Participants — p=0.14
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=70 Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes Mellitus
Type 1 Diabetes · Pregnancy, High Risk
Primary: Neonatal Hypoglycemia — 49.2; 50.1 mg/dL
N/A N=90 Fibroblast Growth Factors 19 and 21 in Gestational Diabetes Mellitus
Gestational Diabetes Mellitus
Primary: The Concentration of Serum FGF19 — 65.96; 124.47 pg/mL
Early Phase 1 N=10 NAC +taVNS in IDM Who Are Poor Oral Feeders
Infant of Diabetic Mother · Oxidative Stress · Vagus Nerve Stimulation
Primary: Daily Oral Feeding Volumes : Difference in Mean Increase — 2.1 ml/kg/day po daily change — p=0.009
Phase 2 N=122 Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)
Infant, Newborn · Infant, Low Birth Weight · Infant, Small for Gestational Age
Primary: Population Pharmacokinetics: V - Volume — 0.6572 l/kg
N/A N=480 Maternal Lifestyle and Neonatal Hypoglycemia
Hyperinsulinemia · Miscarriages · Pregnancy
Primary: Neonatal Hypoglycemia — 3; 15 neonates
Phase 4 N=54 Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Gestational Diabetes · Diabetes, Gestational · Pregnancy in Diabetes
Primary: Proportion of Women Who Are Eligible, Screened, Enroll and Remain in the Study — 25; 26 Participants — p=0.9
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
N/A N=962 Early Gestational Diabetes Screening in the Gravid Obese Woman
Gestational Diabetes · Obesity
Primary: Number of Participants With a Composite Perinatal Outcome — 235; 261 Participants
N/A N=95 Early Screening and Treatment of Women With Prediabetes in Pregnancy
Diabetes · Pregnancy
Primary: Number of Patients With a Diagnosis of Gestational Diabetes at 26 Weeks Gestation. — 19; 23 Participants — p=0.32
N/A N=213 Mobile Diabetes Management
Diabetes
Primary: HBA1c at One Year — 8.5; 7.7; 7.9; 7.9 percentage of HbA1c — p=0.027
Phase 3 N=911 IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.
Angina, Unstable · Cardiovascular Diseases · Heart Diseases
Primary: Progression of Acute Coronary Syndrome to Myocardial Infarction — 200; 242 participants — p=0.28
N/A N=106 Lipid Metabolism in Gestational Diabetes
Gestational Diabetes · Hyperlipidemia
Primary: Cholesterol — 204; 201 mg/dl
Phase 4 N=108 Detemir Versus NPH for Type 2 Diabetes Mellitus in Pregnancy
Diabetes Mellitus, Type 2
Primary: Number of Neonates With Composite Adverse Neonatal Outcome — 31; 35 Participants
Phase 4 N=395 Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo
Mild Gestational Diabetes
Primary: Mean Fetal Weight at Birth — 3355; 3322 grams
N/A N=25 Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Pregnancy Complications
Primary: The Number of Participants Who Achieved a Hemoglobin A1C <7% — 5; 12 Participants
Phase 4 N=36 Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Disorder of Glucose Regulation
Primary: Normalization of Glucose Levels — 9; 2; 4 Participants — p=.035
Phase 3 N=431 Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial
Intraventricular Hemorrhage (IVH) · Bleeding in the Brain · Prematurity
Primary: IVH at 5 Postnatal Days — 25; 40 IVH
Phase 2 N=106 Utility of [F-18] fluoroDOPA for Neonatal Hyperinsulinism
Congenital Hyperinsulinism · Hyperinsulinism · Persistent Hyperinsulinemic Hypoglycemia of Infancy
Primary: The Accuracy of FDOPA PET to Identify Focal Forms of Hyperinsulinism — 40; 6; 3; 46 Participants
Phase 2 N=121 IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity
Retinopathy of Prematurity (ROP)
Primary: Severity of Retinopathy of Prematurity (ROP) as Compared to the Severity of ROP in an Untreated Control Population — 14; 24; 4; 4 participants — p=0.0642
Phase 1 N=22 PED NEONAT 20-000599 Fetal Body Composition
IUGR · Gestational Diabetes · Pregnancy Related
Primary: Maternal Visceral Adipose Tissue Volume — 97593; 169626; 96787 mm3
N/A N=80 The Role of Umbilical Cord Thickness in Prediction of Fetal Macrosomia in Patients With Gestational Diabetes Mellitus
Gestational Diabetes
Primary: The Number of Participants Who Were Diagnosed With Fetal Macrosomia (Birth Weight) — 17; 0 participants
Phase 2 N=31 Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Non Insulin Dependent Diabetes · Pregnancy
Primary: Blood Glucose Measurements — 97.38; 95.04; 97.00; 92.38 mg/dL
N/A N=5,156 TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk
Diabetes Mellitus, Type 1
Primary: Number of Participants With Type 1 Diabetes Mellitus — 82; 91 participants
N/A N=177 Diabetes and Lipid Accumulationand Heart Transplant
Diabetes Mellitus · Heart Failure
Primary: Myocyte Lipid Accumulation as Oil Red-O Positive Biopsie — 54; 21; 0 Endomyocardial Biopsies
Phase 4 N=221 Metformin Versus Insulin in Gestational Diabetes
Gestational Diabetes
Primary: Birth Weight Per Arm — 3604; 3589 g
Phase 2 N=69 Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
Myotonic Dystrophy Type 1
Primary: Change From Baseline to Week 24 in Distance Walked as Assessed by the Six-minute Walk Test (6MWT) Distance — 12.40; 20.11 meters
Phase 3 N=153 Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Gestational Diabetes Mellitus · Type 2 Diabetes Mellitus · Metabolic Syndrome
Primary: Insulin Secretion-Sensitivity Index (IS-SI) — 418.4; 333 index — p=<0.04
N/A N=105 Glycemic Control Using Insulin Levemir Versus Insulin NPH for Diabetes in Pregnancy
Diabetes, Gestational · Diabetes, Type 2
Primary: Glycemic Control — 109.5; 107.4 mg/dL
N/A N=60 Fundus Findings and Thiol-Disulfide Homeostais
Gestational Diabetes · Eye Diseases · Retinal Disease
Primary: Glucose Levels of the Groups in Pregnant Women With Impaired Blood Sugar and/or Gestational DM — 111.67; 154; 83.06; 88.15 mg/dl