N/A N=30 Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study
Myopia · Hyperopia
Primary: Flap Thickness Accuracy Within the Central Zone at Month 3 Postoperative — 125.8 micrometers
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N/A N=94 Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
Astigmatism · Cataract
Primary: Keratometric Correction Index — 0.51 index
N/A N=82 Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
Cataract
Primary: Residual Refractive Astigmatism — .21; .22 diopters
N/A N=37 Corneal Incisions With the IntraLase iFS Femtosecond Laser System
Cataract
Primary: Demonstration That the Femtosecond Laser Consistently Produces Desired Incisions. — 2.75; 2.74 mm
N/A N=114 VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
Myopia · Refractive Errors
Primary: Variability of the Refractive Predicatibility — -0.22 Diopters
Phase 4 N=40 Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK
Myopia · Astigmatism
Primary: 1 Day Postoperative Lasik Uncorrected Visual Acuity — -0.04; -0.05; 0.06 LogMar
N/A N=21 Feasibility of iFS™ for Intrastromal Arcuate Keratotomy (ISAK) Procedures
Refractive Astigmatism
Primary: Change in Refractive Astigmatism — -0.97; -0.81 Diopter of cylinder change
N/A N=72 Technolas 217z Laser With Zyoptix Aspheric Algorithm Used for the LASIK Treatment of Myopia and Myopic Astigmatism.
Myopia · Astigmatism
Primary: Percentage of Eyes With Uncorrected High Contrast Distance Visual Acuity of 20/40 or Better — 99.2 percentage of eyes
N/A N=14 A Comparison of LASIK Outcomes Using Two Femtosecond Lasers
Myopia · Astigmatism
Primary: ETDRS Uncorrected Visual Acuity — 5; 5 Eyes
N/A N=30 Clinical Investigation of the WaveLight® EX500 Excimer Laser
Hyperopia · Hyperopic Astigmatism
Primary: Percentage of Eyes With Manifest Refraction Spherical Equivalent (MRSE) Within ±0.50 Diopter (D) at Refractive Stability — 98.3 percentage of eyes — p=<0.0001
N/A N=33 LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser
Myopia
Primary: Evaluation of LASIK Flap Thickness — 105.8; 112.9 micrometers — p=.003
N/A N=168 WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap
Myopia
Primary: Percentage of Eyes With Uncorrected Distance Visual Acuity (UCDVA) of 20/40 or Better (in Eyes With Preoperative Best Corrected Distance Visual Acuity (BCDVA) of 20/20…
Phase 1 N=357 Use of the VisuMax™ Femtosecond Laser
Myopia
Primary: Effectiveness- Predictability of Participant Refractive Outcomes — 291; 306 Participants
N/A N=15 Glaucoma Surgery Using the ViaLase Laser System
Glaucoma · Glaucoma, Open-Angle
Primary: Mean IOP — 12.7 mmHg
N/A N=88 A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery
Myopia
Primary: Percentage of Participant Eyes With an Uncorrected Visual Acuity of 20/20 or Better — 94; 83 percentage of participant eyes
Phase 2 N=40 Safety and Effectiveness of Arcuate Incisions Performed With the iFS Femtosecond Laser System
Corneal Astigmatism
Primary: Reduction of Astigmatism — -0.75; -0.88 diopter
N/A N=59 WaveLight® Refractive Flap Accuracy Study
Refractive Error
Primary: The Difference Between Achieved Flap Thickness at Day 1 Postoperative as Assessed by OCT and Expected Flap Thickness as Determined Pre-operatively — 14.996; 13.644 microns
Phase 4 N=80 GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients
Corneal Epithelium Defect
Primary: Epithelial Healing After Laser Assisted in Situ Keratomileusis (LASIK) Surgery — 4.3; 3.5; 9.2; 9.0 Clock Hours
N/A N=97 WaveLight® Refractive Myopic Study
Refractive Error
Primary: Least Squares Mean Difference in Binocular UCVA at 1 Month Post-Treatment and Pre-Treatment Binocular BCVA — -0.0519 logMAR
N/A N=300 Patient Reported Outcomes With WaveLight LASIK
Myopia
Primary: Patient Satisfaction — 285 Participants
Phase 2 N=137 Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients
Dry Eye Syndromes
Primary: Percentage of Patients With Clinical Success at Month 6 — 64.3; 58.1 Percentage of Patients
Phase 3 N=170 Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
Myopia
Primary: Percentage of Eyes With Loss of More Than 2 Lines Best Spectacle Corrected Visual Acuity (BSCVA) — 0 percentage of eyes
N/A N=400 An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) Therapy
Dry Eye Syndromes
Primary: Percentage of Patients in Each Category of the Dry Eye Workshop Severity (DEWS) Scale — 65.0; 29.0; 4.2; 1.8 Percentage of Patients
N/A N=84 Conventional Surgery vs. Verion/VerifEye
Cataract · Astigmatism
Primary: Residual Refractive Cylinder — 0.28; 0.33 Diopters
N/A N=94 Simultaneous TransPRK and Corneal Collagen Cross-Linking
Keratoconus
Primary: Change in LogMAR Corrected Distance Visual Acuity (CDVA) — -0.13; -0.05 LogMAR CDVA — p=0.03
Phase 2 N=621 Study of Cyclosporine in Post-LASIK Patients
Laser In Situ Keratomileusis
Primary: Time to Cure — 189.0; 194.0; 189.0 Days
N/A N=600 Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism
Cataract
Primary: Percent Reduction in Manifest Cylinder — 74.6; 19.9 percent reduction in manifest cylinder
Phase 3 N=212 Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
Myopia · Hyperopia
Primary: Percentage of Eyes With Manifest Refraction Spherical Equivalent (MRSE) +/- 0.50 D — 94.78 Percentage of Eyes
N/A N=70 Clinical and Refractive Outcomes After Contoura® Refractive Surgery Planned Using Phorcides Surgery Planning Software
Refractive Errors
Primary: Residual Refractive Cylinder — 0.04 diopters
N/A N=176 A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System
Myopia · Astigmatism
Primary: Percentage of Eyes Achieving Uncorrected Visual Acuity (UCVA) of 20/40 or Better at Refractive Stability in Eyes With Best Spectacle-corrected Visual Acuity (BSCVA) of…