Phase 3 N=40 Treatment of Persistent Pulmonary Hypertension in Neonates With Nebulized Magnesium Sulfate
Magnesium Sulfate - PPHN
Primary: Mean Airway Pressure (cm H2O) — 14.1; 13.8; 13.7; 13.25 (cm H2O) — p=0.83
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Magnesium Sulfate vs Placebo for Placental Abruption
Abruptio Placentae
Primary: Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours — 12; 10 participants — p=0.68
N/A N=192 Magnesium Sulfate Versus Nifedipine for the Acute Tocolysis of Preterm Labor: A Prospective, Randomized Trial
Obstetric Labor, Premature
Primary: Number of Participants With Prevention of Preterm Delivery for 48 Hours With Attainment of Uterine Quiescence — 80; 72 Participants — p=0.01
Phase 4 N=50 Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation
Asthma
Primary: Change in Forced Expiratory Volume in One Second (FEV1) % — 3.6; 5 Percentage of FEV1
Phase 2 N=66 Magnesium Sulfate for Analgesia in Pediatric Transplant
Postoperative Pain
Primary: Total Opioid Requirement — 3.31; 5.27; 10.2; 4.1 OME/kg/d
Phase 4 N=66 Magnesium Sulfate in Obese Preeclamptics
Preeclampsia
Primary: Maternal Serum Magnesium Level at 4 Hours After Administration — 3.53; 4.41 mg/dL
Phase 2 N=52 Timely Intravenous Magnesium for Asthma in Children
Asthma
Primary: Enrollment — 18; 17; 17 Participants
N/A N=301 Tocolysis for Preterm Labor
Preterm Labor
Primary: The Primary Outcome Measure of This Research is to Compare the Efficacy of the Three Clinically Used Tocolytic Agents in a Prospective Study That Will Allow Direct…
Phase 3 N=208 Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis
Sickle Cell Disease
Primary: Hospital Length of Stay (Hours) — 56; 47 hours — p=0.24
N/A N=47 Use of Cheetah® Cardiac Monitoring System to Guide Discontinuation of Magnesium Sulfate in Women With Severe Preeclampsia
Preeclampsia With Severe Features
Primary: Duration of Magnesium Sulfate Use in the Postpartum Period Defined as the Duration in Hours Between Delivery and Discontinuation of Magnesium Sulfate. — 21.6; 24 hours
Phase 3 N=59 A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn
Pulmonary Hypertension, Familial Persistent, of the Newborn
Primary: Time on Inhaled Nitric Oxide (iNO) Treatment After Initiation of Intravenous (IV) Study Drug For Participants Without Treatment Failure — 4.1; 4.1 days — p=0.9850
Phase 2 N=66 Milrinone in Congenital Diaphragmatic Hernia
Congenital Diaphragmatic Hernia · Persistent Pulmonary Hypertension of the Newborn · Hypoxemic Respiratory Failure
Primary: Oxygenation Response — 4.2; 2.6 Change in Oxygenation Index
Phase 3 N=60 Magnesium vs Placebo for Tonsillectomy
Pain
Primary: Postoperative Pain — 30; 45 scores on a scale*minutes
Phase 4 N=80 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients
Pre-eclampsia Aggravated
Primary: TOF 0.9 Achieving Time — 1.6; 2.1 minutes
Phase 2 N=92 Magnesium for Peroral Endoscopic Myotomy
Esophageal Spasm
Primary: Esophageal Symptoms Questionnaire Score (ESQ) — 24; 35 score on a scale
Phase 2 N=44 Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE)
Pseudoxanthoma Elasticum
Primary: Von Kossa Staining Per Unit Area of Dermis — -0.0033; 0.0010; 0.0087; 0.0123 microns
N/A N=261 Intravenous Magnesium Infusion in Patients Undergoing Cardioversion of Atrial Fibrillation Trial
Atrial Fibrillation
Primary: Number of Participants With Successful Cardioversion of Atrial Fibrillation to Sinus Rhythm — 114; 111 Participants
Phase 3 N=1,700 Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial
Cerebrovascular Accident
Primary: Modified Rankin Scale — 2; 2 units on a scale — p=0.28
Phase 2 N=125 Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia
Bronchopulmonary Dysplasia of Newborn
Primary: Safety Based Upon Number of Participants With Hypotension — 1; 0; 0; 0 Participants
Phase 3 N=50 A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients
Postoperative Pain
Primary: Duration of Postoperative Analgesia — 334; 280 time in minutes
Phase 3 N=130 Evaluation of the Role of Magnesium in Prevention of AF Post Cardiac Surgery
Atrial Fibrillation (AF) · Magnesium Sulfate · Post Cardiac Surgery Patients
Primary: Number of Participants With New Episodes of Atrial Fibrillation — 12; 27 participants
N/A N=37 Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department
Renal Colic
Primary: Pain Score Change — -3.4; -3.6 Units on a Scale — p=0.771
Phase 3 N=157 Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
Migraine · Headache
Primary: 30 Minute Pain Score — 3; 3; 3 score on a scale
Phase 3 N=173 Premedication Trial for Tracheal Intubation of the NEOnate
Premedication · Endotracheal Intubation
Primary: Number of Patients With Prolonged Desaturation — 54; 53 Participants — p=0.38
N/A N=50 The Effect of Magnesium Sulfate Infusion on the Quality of Recovery of Ambulatory Patients
Pain · Opioid Use, Unspecified, Uncomplicated
Primary: Quality of Recovery Scores Post Operative — 183; 159 units on scale 40 (low) - 200 (high)
Phase 3 N=1,316 Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Infant, Newborn, Diseases · Other Preterm Infants · Infant, Small for Gestational Age
Primary: Survival Without Bronchopulmonary Dysplasia (BPD) — 346; 320 Participants
Phase 4 N=48 Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
Neuromuscular Block
Primary: Latency — 139.70; 151.30; 147.80 seconds — p=0.9651
Phase 2 N=102 Randomized Trial of Maternal Progesterone Therapy
Congenital Heart Disease · Periventricular Leucomalacia · Brain Development
Primary: Motor Scale of the Bayley Scales of Infant and Toddler Development-III — 90.0; 87.5; 88.7 score on a scale
Phase 4 N=176 Use of Nitrous Oxide Donor for Labor Induction in Women With PreEclampsia
Preeclampsia · Labor, Premature
Primary: Cesarean Delivery Rate — 29; 22 Participants
Phase 3 N=65 Furosemide vs. Placebo for Severe Antepartum Hypertension
Pre-Eclampsia · Hypertension in Pregnancy · Pregnancy Complications
Primary: Mean Systolic Blood Pressure During Hour After Study Drug — 147; 152 mmHg