30 closest matches · ranked by relevance
Depressive Disorder, Major
Primary: Percentage of Participants With Depressive Recurrence After Time (t) in Days — 0.68; 2.11; 1.37; 2.11 percentage of participants — p=<0.001
Major Depressive Disorder
Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Depressive Disorder, Major
Primary: Time to First Relapse During the Double-Blind Treatment Period (DBTP) — NA; NA days — p=0.0212
Major Depressive Disorder
Primary: Phase C: Time-to-Relapse by Any Criteria as Defined in Blinded Addendum — 63.0; 63.0 days — p=0.5100
Depressive Disorder, Major
Primary: Depressive Symptoms — 7.5; 10.5 units on a scale
Major Depressive Disorder
Primary: Percentage of Subjects With Treatment Emergent Adverse Events (TEAEs) — 66.7 percentage of subjects
Depression · Pregnancy Related · Antenatal Depression
Primary: Number of Participants Experiencing Relapse of Depression — 81; 111 Participants
Major Depressive Disorder With Mixed Features
Primary: Mean Change From Baseline to the 6-week Study Endpoint in Montgomery-Asberg Depression Rating Scale (MADRS) Total Scores — -20.5; -13.0 units on a scale — p=<0.0001
Depression
Primary: Time to Remission — 13.67; 11.33 weeks
Depression
Primary: Depressive Relapse or MDD — 18; 18.3; 32.7 % patients who relapsed — p=.42
Depression · Major Depressive Disorder
Primary: Time to Relapse (Days) — NA; NA Days
Depressive Disorder, Major · Depressive Disorder, Treatment-Resistant
Primary: Incidence of Treatment Emergent Adverse Events (AEs) [Safety and Tolerability] — 9; 15; 12; 0 Participants
Major Depressive Disorder
Primary: Time to Relapse Following Randomization to the Double-blind (DB) Phase: Estimated Probability (Percent) of Relapse at DB Day 185 — 30.2; 14.3 percent estimated…
MDD
Primary: Depression Severity Changes Scored From Patient Health Questionnaire (PHQ9) — 5; 6.71; 8.14; 9.14 score on a scale
Major Depressive Disorder
Primary: Quick Inventory of Depressive Symptoms — 46.6; 41.8; 46.0 percentage of participants
Depressive Disorder, Major
Primary: Mean Percent Change From Baseline in MADRS Score — -7.7; -7.4; -8.8; -6.2 percentage change from baseline
Major Depressive Disorder
Primary: Change From Baseline in Hamilton Depression Rating Scale (HAMD-17) Total Score at Weeks 8 — -9.0; -7.4 Scores on a scale — p=0.121
Bipolar Disorder
Primary: Number of Participants With Relapse of Major Depressive Episode Within 1 Year — 4; 5 Participants
Major Depressive Disorder
Primary: Change in the MADRS10 Total Score From Baseline to Day 28 — -15.1; -12.9 score on a scale
Major Depressive Disorder
Primary: Montgomery-Asberg Depression Rating Scale — -14.7; -10.2 units on a scale — p=<0.0001
Depression
Primary: Change From Baseline in Hamilton Depression Rating Scale at 8 Weeks — 11.81; 9.41 score on a scale
Major Depressive Disorder · Depression, Unipolar · Recurrence
Primary: Change in HAM-D-17 Total Score — -5.8; -9.5 units on a scale
Bipolar Disorder
Primary: Change in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -9.64; -5.32 units on a scale
Major Depressive Disorder
Primary: Mean Change in the Montgomery Åsberg Depression Rating Scale (MADRS) — -10.12; -6.39 units on a scale — p=<0.001
Major Depressive Disorder
Primary: Percentage of Participants Who Meet Criteria for Re-emergence of Depressive Symptoms Estimated by Kaplan-Meier Product Limit Method (Double-blind Randomized Withdrawal…
Depression
Primary: Number of Participants in Remission According to the Longitudinal Interval Follow-up Evaluation (LIFE) and the Hamilton Rating Scale for Depression (HRSD) — 187; 170…
Major Depressive Disorder
Primary: Change in the MADRS10 Total Score From Baseline to Day 28 — -14.8; -13.9 score on a scale
Major Depressive Disorder
Primary: Change From Baseline in Behavior Rating Inventory of Executive Function - Adult Version Global Executive Composite T-score (BRIEF-A GEC T) at Week 9, Last Observation…
Depressive Disorder, Major
Primary: Change From Baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score at Week 8/Withdrawal — -13.9; -14.4; -12.9 Scores on a scale — p=0.853