Clinical Trial Search

Primary: Number of Participants With "Complete Response" and "Partial Response" — 17; 2; 13; 15 participants

Primary: The Proportion of Subjects Achieving Pleurodesis Without Recurrence. — 17; 12 Participants

Primary: Overview of Adverse Events — 28; 23; 12; 1 participants

Primary: Chest X-ray Results on Day 3 After Pleurodesis — 5; 6; 5; 8 Participants — p=0.863

Primary: Proportion of Evaluable Participants Who Are Progression-free at 6 Months Based on the Response Evaluation Criteria for Solid Tumors (RECIST) — 47.8 percentage of…

Primary: Malignant Pleural Infiltration Identification — 12; 27; 9; 4 Participants — p=0.023

Primary: Disease Control Rate (DCR) — 75 percentage of participants

Primary: Best Overall Response by RECIST Criteria (Version 1.0) — 3; 0; 7; 6 eligible, treated participants

Primary: To Evaluate the Efficacy of the Treatment — 1.9 Months

Primary: PD-L1 Prevalence IHC — 21; 14; 8; 27 Participants

Primary: Phase II: Progression Free Survival Measured as Time From Randomization to First Observation of Objective Disease Relapse or Progression — 6.7; 6.8; 5.26 months

Primary: Change in Ratio of Intratumoral Cytotoxic T Cells to Regulatory T Cells (CD8/Treg) — 8.6 no unit of ratios with same units(%) — p=0.109

Primary: Overall Survival — 17.6; 15.5 Months — p=0.2840

Primary: Progression Free Survival (PFS) as Assessed by Independent Radiological Review — 2.5; 3.4 months — p=0.76

Primary: Ability of PD-L1 to Predict Response — 0.377 Youden index

Primary: Objective Response (Partial and Complete) Per RECIST — 1 participants

Primary: Overall Survival (OS) — 20.5; 18.1 months — p=0.14

Primary: Overall Survival (OS) — 8.5; 8.0 months — p=0.58

Primary: Number of Participants With Progression Free Survival (PFS) Responders and Non-responders at Month 6 — 26; 51 Participants

Primary: Progression-free Survival — 3.0; 3.4 months

Primary: Best Disease Response After a Maximum of Six Cycles. — 0; 23; 23; 6 Participants

Primary: Total Days of Mechanical Ventilatory Support — 6.51; 4.02 days

Primary: Disease Control Rate at 4 Months — 8 Participants

Primary: Progression-Free Survival — 3.0 months

Primary: Progression Free Survival Rate at 6 Months — 56 percentage of participants

Primary: To Determine the Rate of Clinical Benefit (i.e. Rate of Complete or Partial Response Plus Stable Disease) at 16 Weeks for Patients With Malignant Mesothelioma Treated…

Primary: Pleural Carcinomatosis Identification (Compared to Standard Biopsies). Qualitative Criteria. — 8; 24; 21; 0 Participants — p=0.0003

Primary: Response Assessment — 0; 0; 0; 0 Participants

Primary: Objective Response Rate, Complete (CR) or Partial (PR) Response — 5 percentage of participants

Primary: Phase 1 Part: Number of Participants With Adverse Events (AEs), Serious Adverse Events (SAEs) and Adverse Drug Reactions (ADRs) — 4; 0; 0; 1 Participants