N/A N=770 Strategies to Assist With Management of Pain
Chronic Low Back Pain
Primary: Composite Pain Severity — 5.6; 5.6 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=525 Integrated Services for Pain: Interventions to Reduce Pain Effectively
Chronic Pain
Primary: Change From Baseline in Average Daily Opioid Dose in Morphine Milligram Equivalents (MME) at Month 12 — -11.6; -6.0 Morphine Milligram Equivalents (MME) — p=0.31
N/A N=850 Pain Program for Active Coping & Training
Chronic Non-malignant Pain
Primary: Pain Impact Assessed Using the 4-Item Version of Brief Pain Inventory-Short Form ("PEGS") — 6.485; 6.645; 5.486; 6.210 score on a scale
N/A N=51 Positive Psychology for Chronic Pain Self-management
Chronic Pain
Primary: Change in Pain Interference — -3.82; .32 T-score
Phase 3 N=65 An Implantable Spinal Cord Stimulation Pain Management System
Chronic Pain · Pain, Intractable · Pain
Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement
N/A N=114 Behavioral Treatments for Chronic Pain
Intractable Pain
Primary: Brief Pain Inventory — 4.5; 5.1 units on a scale — p=.27
N/A N=217 An Evaluation of MBSR and CBT for Veterans With Chronic Pain
Chronic Pain · Pain
Primary: Pain Interference Subscale of Brief Pain Inventory (BPI) — 4.7; 4.8; 4.9; 4.4 score on a scale
N/A N=401 Improving Chronic Pain Treatment in Primary Care
Pain · Chronic Disease · Depression
Primary: Adjusted Change in Pain-related Function (Roland Disability Score) — -1.4; -0.2 units on a scale
N/A N=20 VANISH for Chronic Low Back Pain
Chronic Low-back Pain
Primary: Assessment of Opioid Use Via Subject Report — 47.5; 21.75 morphine milligram equivalent
Phase 4 N=19 Buprenorphine and Methadone for Opioid-dependent Chronic Back Pain Patients
Low Back Pain
Primary: Analgesia — 36.3; 71.8 units on a VAS scale — p=0.097
N/A N=163 Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings
Opioid-Related Disorders
Primary: Pain Interference Based on the Brief Pain Inventory — 5.01; 4.67 units on a scale
Early Phase 1 N=22 Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
Chronic Pain · Opiate Dependence · Lower Back Pain
Primary: Change in Quantitative Pain Testing Following Active TMS Compared to Baseline — 1.4; .3 Change from Baseline (degrees C) — p=.83
N/A N=115 Opioid Treatment and Recovery Through a Safe Pain Management Program
Depression · Opioid Use · Chronic Pain
Primary: Odds of Morphine Equivalent Daily Dose (MEDD) of Opioid Prescription >=50 mg — 0.209; 0.417; 0.185; 0.364 odds of prescription high dose — p=0.956
N/A N=376 Patient Activation to Address Chronic Pain and Opioid Management in Primary Care
Chronic Pain
Primary: Patient Activation — 65.8; 65.2; 67.3; 67.7 units on a scale
N/A N=57 Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial
Chronic Pain · Cognitive Impairment
Primary: Change in Pain Interference — -0.9; 0.2 units on a scale
N/A N=21 Treatment of Insomnia Secondary to Chronic Pain
Insomnia · Pain
Primary: Insomnia Severity — 6.0; 12.8; 4.4; 13.0 units on a scale — p=0.010
N/A N=30 Brief Cognitive Behavioral Therapy for Chronic Pain
Chronic Pain · Musculoskeletal Pain
Primary: West Haven-Yale Multidimensional Pain Inventory - Interference (WHYMPI-I) to Assess Change at Follow up — 3.43; 3.10 units on a scale — p=.486
N/A N=200 Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes
Opioid-use Disorder · Medication Assisted Treatment · Chronic Pain
Primary: Retention on Buprenorphine Treatment According to TimeLine Follow-Back - 3-months — 81.1; 75.4 days
N/A N=38 Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Chronic Pain · Chronic Lower Back Pain · Back Pain
Primary: Changes in Patient Reported Pain and Discomfort — 47; 13; -30; -18 percent change from baseline
Phase 2 N=90 Clinical Trial of Integrated Treatment for Pain and Opioid Dependence
Opiate Dependence · Chronic Pain
Primary: Pain Intensity — 5.43; 5.92; 5.28; 4.75 units on a scale
N/A N=109 Self-Management Interventions for Chronic Pain Relief With Cancer Survivors
Chronic Pain
Primary: Change in Pain Intensity — -1.61; -1.35 score on a scale — p=0.809
N/A N=116 Mindful Action for Pain
Chronic Pain
Primary: Brief Pain Inventory (BPI) Pain Interference Subscale Change — 6.77; 7.31; 7.38; 5.40 units on a scale
N/A N=779 Acupuncture Approaches for Chronic Pain
Chronic Pain · Osteoarthritis · Neck Pain
Primary: Pain Interference as Measured by the Brief Pain Inventory (BPI) (Intent to Treat Model) — 6.0; 6.1; 5.1; 4.8 Units on a Scale — p=0.0691
N/A N=240 Strategies for Prescribing Analgesics Comparative Effectiveness Trial
Back Pain · Osteoarthritis
Primary: Brief Pain Inventory Interference Scale — 3.7; 3.7; 3.4; 3.6 units on a scale
N/A N=99 PainTracker Self-Manager: a Web-based Platform to Promote and Track Chronic Pain Self-management
Chronic Pain
Primary: Chronic Pain Self-efficacy — 27.33; 33.66; 28.39; 35.57 score on a scale — p=<0.05
N/A N=402 EMPOWER: Randomized Trial of Online Chronic Pain Management Program to Reduce Reliance on Opioid Analgesic Medications
Chronic Pain
Primary: Decrease in Morphine Equivalent Dose (MED) — 85; 105 Participants
N/A N=1,372 Cognitive Behavioral Therapy and Chronic Pain Self-Management Within the Context of Opioid Reduction: The EMPOWER Study
Chronic Pain
Primary: Opioid Tapering Success — 86; 61; 81; 0 Participants
Phase 4 N=86 Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
Chronic Pain
Primary: Pain Intensity — 11; 29 Participants
Phase 2 N=35 Meditation-CBT for Opioid-treated Chronic Low Back Pain
Chronic Pain · Low Back Pain
Primary: Health-Related Quality of Life: Averaged Pain Severity — -0.5; 0.4 units on a scale
N/A N=23 4-week Mindfulness Program for Adults With Chronic Pain
Chronic Pain
Primary: Feasibility - Study Retention — 0.96 Proportion of participants