Clinical Trial Search

Primary: Percentage of Patients That Achieve Maximal Surgical Debulking — 10 Participants

Primary: Tumor Marker CA125 — 189; 4 U/mL — p=<0.001

Primary: P16 Evaluation in Ovarian Germ Cell Tumors — 7; 4; 0; 6 units on a scale — p=0.001

Primary: Number of Protocol Defined Adverse Events in Patients Receiving Neoadjuvant Carboplatin, Paclitaxel, and Bevacizumab — 7 protocol defined adverse events

Primary: PFS — 29.8 Months

Primary: Overview of Treatment-emergent Adverse Events (TEAEs) — 3; 13; 11; 2 Participants

Primary: Percentage of Patients in Remission at 1 Year — 38.1; 38.8 percentage of participants

Primary: Maximum-tolerated Dose of Pemetrexed With a Day 2 i.p. Cisplatin (75 mg/m2) and Day 8 i.p. Paclitaxel (60 mg/m2) — 500 mg/m2

Primary: 9-month Progression Rate Post-randomization — 0.386; 0.347; 0.245 Porportion of participants — p=0.065

Primary: Number of Patients With Treatment-emergent Adverse Events — 12; 6; 6; 12 Participants

Primary: Overall Survival — 32 months

Primary: Progression-Free Survival (PFS) Assessed by Investigator as Per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1) - Intent-to-Treat (ITT) Population…

Primary: Median Progression-free Survival — 3.2; 4.5 months

Primary: Number of Participants With Dose-Limiting Toxicity (DLT) — 0; 0; 0; 0 Participants

Primary: Tolerated Dose — 80 mg/m^2

Primary: Inter-rater Reliability of Positron Emission Tomography (PET) Maximum Standardized Uptake Value (SUVmax) - Individual Intra-class Correlation Coefficients by Location…

Primary: Tumor Response — 16.7 percentage of patients

Primary: 6 Month Progression-free Survival (PFS) — 13 participants

Primary: Overall Survival at 2 Years and 5 Years — 93; 85 percentage of participants

Primary: Clinical Response Rate. — 0; 19; 21; 60 percentage of participants

Primary: Cell Proliferation in the Fallopian Tube Fimbriae as Measured by Ki-67%+ — 8.3 percentage of positively stained cells

Primary: Progression-free Survival at 6 Months — 13.6 percentage of participants

Primary: Number of Patients (%) in Which Sentinel Node(s) Are Detected After Injection of Blue Dye and Tracer in the Ovarian Ligaments. — 21 participants

Primary: Tumor Response — 23.4 Percentage of participants

Primary: Number of Participants Assessed for Safety and Tolerability as Assessed by NCI CTCAE v3.0 — 3; 3; 4; 2 Participants

Primary: Efficacy Patient Level — 26.9 percentage of participants

Primary: Number of Patients With Response — 9; 21; 24 Participants

Primary: Objective Response Rate (ORR) — 2; 0 Participants

Primary: Response Rate — 1; 2; 4 participants

Primary: Number of Patients With Dose-limiting Toxicities (DLTs) — 0; 0 Participants