Phase 3 N=38 Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis
Uveitis · Uveitis, Posterior · Uveitis, Anterior
Primary: Adverse Events — 27; 1 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=261 Efficacy and Safety of Adalimumab in Subjects With Inactive Uveitis
Uveitis
Primary: Time to Treatment Failure on or After Week 2 — 8.3; NA; 5.6; NA months — p=0.004
Phase 2 N=12 A Safety Study of Intravitreal PP-001 in Patients With Chronic, Non-Infectious Uveitis
Non-infectious Uveitis
Primary: Evaluation of Safety and Tolerability by Determining Treatment Emergent Adverse Events — 12 Participants
Phase 2 N=7 Lucentis for Inflammatory Macular Edema Trial
Uveitis · Cytoid Macular Edema
Primary: The Mean Change at 3 Months in BSCVA From Baseline — 13 letters
Phase 2 N=16 Safety and Efficacy of AIN457 in Noninfectious Uveitis
Non-infectious Uveitis
Primary: Number of Participants With Adverse Events (AEs), Serious Adverse Events (SAEs) and Who Died — 0; 0; 1; 1 participants
Phase 2 N=31 Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis
Uveitis
Primary: The Primary Outcome is the Time to Recurrence of Uveitis in Participants of Each Treatment Group, During or After Tapering of Oral Prednisone to a Dose of 7.5 mg/Day, or…
Phase 2 N=31 Adalimumab (Humira) in the Treatment of Refractory Non-infectious Uveitis
Uveitis
Primary: Cumulative Endpoint — 21 participants
Phase 2 N=58 Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis
Uveitis
Primary: Percentage of Participants With at Least 2-step Reduction in Vitreous Haze (VH) or Prednisone Dose <10 mg/Day at Week 16 — 30.0; 46.1 Percentage of participants — p=0.2354
N/A N=5 Pegaptanib Therapy in Non-Infectious Uveitic Cystoid Macular Edema
Uveitis · Cystoid Macular Edema
Primary: Improvement in VA ETDRS >/= 15 Letters — 1 participants
Phase 4 N=255 Multicenter Uveitis Steroid Treatment (MUST) Trial
Uveitis
Primary: Change in Best-corrected Visual Acuity (Change in the Numbers of Letters Read From a Standard ETDRS Eye Chart) From Baseline to 24 Months in Eyes With Uveitis — 6.0; 3.2…
Phase 3 N=229 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis
Intermediate Uveitis · Posterior Uveitis
Primary: Percentage of Patients With Vitreous Haze (Ocular Inflammation) Score of Zero — 35.5; 46.8; 11.8 Percentage of Patients
Phase 3 N=160 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis
Uveitis · Uveitis, Posterior · Uveitis, Anterior
Primary: Number of Subjects Demonstrating ≥ 15 Letter Improvement From Baseline in Best Corrected Visual Acuity at 24 Weeks — 45; 10 Participants — p=<0.001
Phase 2 N=8 Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study)
Uveitis
Primary: Number of Participants Experiencing a Treatment Response by Week 16 — 4; 2 Participants
Phase 2 N=45 A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis
Non-infectious Anterior Uveitis
Primary: Anterior Chamber Cell Grade at Week 8 — -0.7; -0.9; -0.5 units on a scale
Phase 1 N=30 Sirolimus as Therapeutic Approach to Uveitis
Uveitis · Intermediate Uveitis · Posterior Uveitis
Primary: Number of Participants With at Least 2-step Decrease in Vitreous Haze (VH) — 4; 4 participants
Phase 2 N=16 A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis
Non-infectious Anterior Uveitis
Primary: Assessment of Both Systemic and Ocular Adverse Events — 2; 5 Participants
Phase 4 N=21 Re-implantation of a Fluocinolone Acetonide Implant for Non-infectious Uveitis Affecting the Posterior Segment
Uveitis
Primary: Number of Eyes With Inflammation Recurrence — 1 eye with inflammation
Phase 3 N=424 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis
Uveitis
Primary: Number of Participants With Adverse Events — 398; 101 participants
Phase 2 N=22 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis
Uveitis · Macular Edema · Uveitis, Posterior
Primary: Change From Baseline in Central Subfield Thickness, Measured Using Optical Coherence Tomography, After Treatment With CLS-TA in Subjects With Macular Edema Following…
Phase 3 N=26 Utilization and Safety of the Mk II Inserter and the Safety of the FAI Insert in Non-Infectious Uveitis
Non-Infectious Uveitis
Primary: The Utilization of the Mk II Inserter From the Day of Treatment Through 7 Days Following Treatment. — 10; 3; 3; 2 Eyes
Phase 3 N=153 Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis
Posterior Uveitis · Intermediate Uveitis · Panuveitis
Primary: Number of Participants With Recurrence of Uveitis in Study Eye Within 6 Months — 28; 22 Participants
Phase 4 N=20 Study of the Effectiveness of Ozurdex for the Control of Uveitis
Uveitis, Intermediate · Uveitis, Posterior
Primary: Number of Participants With Absence of Intraocular Inflammation at 6 Months — 12 Participants
Phase 4 N=5 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients
Uveitis · Anterior Uveitis · Intermediate Uveitis
Primary: Number of Participants With Photographic Haze Reduced to Grade 0 or Down 2 Steps Documented With Fundus Photography — 3; 1; 1 Participants
Phase 2 N=25 Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis ,
Non-infectious Intermediate Uveitis · Non-infectious Posterior Uveitis · Non-infectious Panuveitis
Primary: Number of Participants With Response Rate for the Individual Response Criteria - in the Study Eye — 3; 3; 0; 1 Participants
Phase 3 N=227 Adalimumab vs. Conventional Immunosuppression for Uveitis Trial
Uveitis
Primary: Corticosteroid-sparing Treatment Success Within the First 6 Months After Randomization — 0.69; 0.54 Cumulative proportion of participants — p=0.029
Phase 2 N=10 Abatacept in the Treatment of Uveitis
Uveitis
Primary: Adverse Events — 0; 0; 0 Participants
Phase 1 N=6 Efalizumab to Treat Uveitis
Uveitis · Macular Edema
Primary: Number of Participants With Systemic Toxicities, Adverse Events, or Infections — 6 Participants
Phase 3 N=139 A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma
Non-infectious Anterior Uveitis · Uveitic Glaucoma
Primary: Anterior Chamber Cell (ACC) Grade = 0 on Day 28 — 38; 32; 44; 15 Participants
Phase 2 N=11 Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis
Uveitis · Intermediate Uveitis · Posterior Uveitis
Primary: Change in Intraocular Pressure (IOP) — -0.1 mm Hg
Phase 3 N=129 Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert
Non-Infectious Uveitis
Primary: Proportion of Subjects With Recurrence of Uveitis in the Study Eye and Overall Summary of Number of Participants With Ocular Treatment-Emergent Adverse Events for the…