Phase 3 N=23 Use of N-Acetylcysteine (NAC) in Fingernail Biting
Onychophagia
Primary: Number of Participants Enrolled Within One Year — 12; 11 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=66 N-Acetyl Cysteine in Pathologic Skin Picking
Pathologic Skin Picking · Neurotic Excoriation · Psychogenic Excoriation
Primary: Yale Brown Obsessive Compulsive Scale (YBOCS) Modified for PSP (NE-YBOCS) — 18.8; 17.6; 16.1; 17.3 units on a scale
N/A N=20 Real-World Evaluation of the Effect of Jublia on Nail Polish
Evaluation of Jublia on Nail Polish With Healthy Toenails
Primary: Observe Stability of Nail Polish as Evidenced by Serial Photography With Efinaconazole Application in Terms of Days — 1.5; 5; 15; 5 days of stability
Phase 2 N=21 Topical Cyclosporine Suspension for the Treatment of Brittle Nails
Brittle Nail Syndrome
Primary: • Number of Patients Receiving at Least a 1-grade Improvement in the Physicians Global Improvement Assessment (PGIA) of Two Target Nails. — 10; 11 patients
Phase 4 N=12 A Study Evaluating the Efficacy and Tolerability of Oral Apremilast for the Treatment of Nail Psoriasis
Psoriatic Nail · Psoriasis Vulgaris · Psoriasis
Primary: Mean Percent Change of mNAPSI (Modified Nail Area Psoriasis Severity Index) at Week 36 Compared to Baseline for All Nails. — 64.1 percentage of reduction in mNAPSI score…
Phase 2 N=29 Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
Onychomycosis
Primary: Clinical Evidence of Complete Clearance of the Treatment-targeted Great Toenail Plus a Negative Fungal Culture at Day 360 — 2; 27 participants
Phase 4 N=22 Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome
Nail Diseases
Primary: Physician Global Improvement Assessment (PGIA) — 5; 2; 7; 1 Fingernails
Phase 4 N=20 Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus Ciclopirox Nail Lacquer
Foot Dermatoses
Primary: Percent of "in Label" Adherent Subjects — 85; 60 percentage of participants
N/A N=5 Early Feasibility Study to Evaluate the Efficacy of the RenewalNail™ Plasma Treatment System in Patients With Onychomycosis (Fungal Nail)
Onychomycosis of Toenail · Onychomycosis
Primary: Mycological Cure — 2 Participants
Phase 2 N=39 N-Acetylcysteine for Pediatric Trichotillomania
Trichotillomania · Hair Pulling
Primary: Massachusetts General Hospital Hair Pulling Scale (MGH-HPS) — 10.70; 13.53 units on a scale
N/A N=26 Early Feasibility Study to Evaluate the Efficacy and Safety of the RenewalNail™ Plasma Treatment System in Patients With Mild to Moderate Onychomycosis (Fungal Nail)
Onychomycosis Due to Trichophyton Rubrum · Onychomycosis Due to Trichophyton Mentagrophytes
Primary: Mycological Cure — 12 Participants
N/A N=8 308nm Excimer Laser for Treatment of Fingernail Psoriasis
Nail Psoriasis
Primary: Modified NAPSI Score (Nail Psoriasis Severity Index) — 6.3; 6.0 units on a scale
Phase 4 N=132 Scoring Clinical Index For Onychomycosis in Toenail Onychomycosis Treating With Itraconazole Capsules
Onychomycosis, Toe
Primary: Percentage of Participants Showing 10 Percent or Higher Response in Scoring Clinical Index for Onychomycosis (SCIO) Score at Week 5 — 25.6 percentage of participants
Phase 3 N=1,381 Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.
Onychomycosis
Primary: Clinical and Mycological Cure of Target Toenail — 22.3; 1 Percentage of participants — p=<0.001
Phase 2 N=50 N-Acetyl Cysteine in Trichotillomania
Trichotillomania
Primary: Massachusetts General Hospital Hairpulling Scale — 17.6; 16.7; 10.4; 16.0 units on a scale
N/A N=27 Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser
Onychomycosis
Primary: The Primary End Point Was the Percentage of Patients With a Negative Mycological Culture. — 12; 10 percentage of participants — p=<0.05
Phase 3 N=139 PinPointe FootLaser for the Treatment of Onychomycosis
Infected Toenails · Onychomycosis
Primary: Nail Bed Clearing