Clinical Trial Search

Primary: Incidence of Surgical Site Infection (SSI) Relating to Intramedullary Nailing for Fixation of Diaphyseal Femoral and Tibial Fractures — 26; 195 Participants

Primary: Number of Participants With Total Wound Infections — 4; 9 participants — p==0.12

Primary: Number of Blood Samples With High Levels of Absorbance Via ELISA for Patients (Greater Than 1.5 Ratio Compared to Control Human Serum) — 48; 53 blood draw samples

Primary: Number of Participants With Tissue Samples Identified With Bacterial DNA According to Highly Sensitive Bacterial Assays — 10; 24; 20 Participants

Primary: Description of the Clinical and Epidemiological Profile of Patients With Infection — 92; 26; 25; 21 Participants

Primary: Incidence of Surgical Site Infection During the Post-operative Follow-up Period — 0; 0; 0 participants

Primary: Cost of Treatments — 1089; 11,973 USD

Primary: Change From Baseline, at Weeks 2, 6 and 12 on the Patient Reported Outcome Measurement Information System (PROMIS) - Physical Function Between the Groups. — 18.65; 17.6…

Primary: Number of Participants With the Presence of Post-Operative Infection — 2; 2 Participants

Primary: Number of Participants Experiencing Clinical Failure — 26; 30 Participants

Primary: Number of Participants With Adverse Events — 5; 4; 1; 6 participants

Primary: Surgeon Attitudes About Using Intra-wound Antibiotics for Spine Surgery — 9; 36; 46 Participants

Primary: Percent of Patients That Complete the Protocol — 61.5; 83.3; 0 percentage of completed patients

Primary: Number of Participants With a Superficial Incisional Surgical Site Infection (SSI) — 13; 7 Participants

Primary: Measurement of Change in Cutibacterium Acnes — 3; 8; 3; 2 Participants — p=0.004

Primary: Resorption of Study Device — 4 Participants

Primary: Positive Cultures — 7; 7 cultures

Primary: Quantify the Tolerability of Tedizolid for Bone and Joint Infections, Both Hardware and Non-hardware Associated — 0; 0 participants

Primary: Number of Participants With a Superficial Incisional Surgical Site Infection (SSI) — 20; 27; 6; 9 Participants

Primary: The Frequency of Definite Failure of Infection Treatment. — 67; 74 Participants

Primary: Visual Analog Scale (VAS) Pain Score — 64; 61 score on a scale

Primary: Participants' Quality of Life at 3 Months — 0.60; 0.59 score on a scale

Primary: Amount (mg) of Narcotics (Oral Morphine mg Equivalents) Used — 16; 10 morphine milligram equivalents (MME)

Primary: Number of Participants With Staphylococcus Aureus Nasal Colonization — 12 Participants

Primary: Constant Scale Evaluation at 3 Months and 12 Months From the Date of Trauma — 40.1; 51.8 units on a scale — p=<0.01

Primary: Surgical Site Infection — 6; 3 participants — p=<0.05

Primary: Rate of Enrollment — 12.5 Participants enrolled per month

Primary: Study Design Feasibility for Preoperative ICG Perfusion Rate as a Predictability Factor for Infection: Measured as Percentage of Patients With Analyzable Data — 0…

Primary: Sensitivity — 96.7 percent of scans with a fracture

Primary: Revision Surgery — 107; 117 Participants