N/A N=278 Transoral Robotic Surgery for rECurrent Tumours of the Upper Aerodigestive Tract
Recurrent Head and Neck Cancer
Primary: Disease-free Survival at 2 Years — 111 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=170 Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery
Head and Neck Cancer · Oropharyngeal Cancer · Hypopharyngeal Cancer
Primary: Number of Participants With Adequate Exposure and Access to Oropharyngeal and Hypopharyngeal Head and Neck Lesions — 147; 23 participants
Phase 3 N=501 Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubes
Otitis Media
Primary: Number of Subjects With Post-surgical Otorrhea — 383; 118 Participants
N/A N=69 Retrospective Health Care Utilisation and Current Quality of Life in Adults With Chronic Otitis Media Who Had a Middle Ear Surgery
Chronic Otitis Media
Primary: Number and Type of Contacts With Health Care Providers — 45; 14; 5; 3 Participants
N/A N=58 Transoral Robotic Surgery (TORS) for Oral and Laryngopharyngeal Lesions Using Da Vinci Robotic Surgical System
Head and Neck Neoplasms
Primary: The Number and Percent of All Evaluable Patients Who Have Successfully Undergone TORS at Each Interim Analysis. — 54 Participants
Phase 2 N=75 OTO-201 for the Treatment of Otitis Externa
Otitis Externa
Primary: Otoscopic Examination: Tympanic Membrane — 6; 8; 8 Participants
Phase 3 N=33 Open-Label Study of OTO-201 for Middle Ear Effusion Evaluating Trans-Tympanostomy Tube Administration
Bilateral Middle Ear Effusion
Primary: Otoscopic Examination: Auricle and Meatus — 1 ears
Phase 2 N=95 Dose Ranging Study of OTO-201 in AOMT
Acute Otitis Media · AOMT
Primary: Number of Subjects With Adverse Events — 19; 14; 4 Participants
N/A N=33 Prospective, Multicenter da Vinci® SP™ Surgical System TORS Study
Oropharyngeal Cancer
Primary: Performance — 0 Participants
N/A N=96 Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose
CerebroSpinal Fluid (CSF) Leak · Chronic Otitis Media · Otospongiosis
Primary: Percentage of Participants With >=3 Diagnostic Rating Using Radlex Scale — 92.63 percentage of participants
Phase 4 N=118 Pain Control Following Sinus Surgery
Sinusitis · Opioid Use · Opioid Abuse
Primary: Pain Severity — 12.4; 8.5 units on a scale
Phase 3 N=266 OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
Otitis Media With Effusion
Primary: Percentage of Participants Who Were Treatment Failures — 24.6; 44.8 percentage of treatment failures
Phase 3 N=266 OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
Otitis Media With Effusion
Primary: Percentage of Participants Who Were Treatment Failures. — 21.3; 45.5 percentage of treatment failures
N/A N=81 Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery
Sleep Apnea, Obstructive
Primary: Apnea Hypopnea Index (AHI) — 44.89; 44.65; 36.87 events per hour — p=<0.05
N/A N=56 High Flow vs Conventional Oxygen in Head and Neck Surgery
Pulmonary Disease
Primary: Proportion of Patients With Post-operative Pulmonary Complication — 2; 11 Participants
N/A N=20 Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
Laryngologic Surgical Procedures
Primary: Average Oxygen Saturation by Pulse Oximetry (SpO2) (Primary Anesthesia Outcome) — 93; 98.7 percentage of saturation (SpO2) — p=0.006
Phase 2 N=39 Open-Label Study of OTO-201 for Treatment of AOMT
Acute Otitis Media · AOMT
Primary: Number of Ears With Otorrhea (Drainage From the Middle Ear) — 8 affected ears
Phase 3 N=370 In-Office Tympanostomy Tube Placement in Children (OTTER)
OME - Otitis Media With Effusion · AOM - Acute Otitis Media
Primary: Procedural Success: — 103; 91 Participants
Phase 3 N=262 Phase 3 Study of OTO-201 in Acute Otitis Externa
Acute Otitis Externa · Swimmer's Ear
Primary: Number of Subjects Considered a Clinical Cure at Day 8 — 91; 63 Participants
N/A N=52 Osteopathic Otitis Media Research Study
Otitis Media With Effusion
Primary: Change in Middle Ear Effusion Over Four Weeks Following an Episode of Acute Otitis Media — 26; 16; 12; 22 Ears — p=0.02
N/A N=72 Balloon Sinus Dilation In Office or OR
Chronic Sinusitis
Primary: Mean Intra-patient Change in SNOT-20 Score at 24 Weeks Post-procedure Compared to Baseline — -1.25; -1.35 scores on a scale
N/A N=453 Childhood Adenotonsillectomy Study for Children With OSAS
Obstructive Sleep Apnea · Snoring
Primary: Improvements in Attention/Executive Domain Index of the Developmental Neuropsychological Assessment (NEPSY) From Baseline to 7 Months. — 7.1; 5.1 units on a scale — p=0.16
N/A N=102 Safety and Efficacy of Laryngeal Mask Airways in Sinonasal Surgery
Conditions Requiring Sinonasal Surgery
Primary: Number of Participants With Presence or Absence of Blood/Secretions in Trachea and Larynx Based on Soiling Score — 12; 10; 15; 21 Participants
Phase 3 N=185 Patient Narcotic Requirements After Outpatient Otolaryngology Procedures
Outpatient Surgery · Pain, Postoperative
Primary: Narcotic Usage — 4.9; 2.0 Pills
N/A N=125 Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Vocal Cord Function in Neck Procedures
Primary: Frequency of Congruence of Nerve Integrity and Vocal Cord Functions — 68; 13; 17; 10 nerves at risk
N/A N=186 Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study
Sleep Disordered Breathing · Obstructive Sleep Apnea · Snoring
Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54
N/A N=20 Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery
Otorhinolaryngologic Surgical Procedures · Laser Therapy
Primary: Lowest Intraoperative Peripheral Oxygen Saturation (SpO2) — 97; 97 percentage of oxygen — p=0.7934
N/A N=101 Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media
Chronic Otitis Media
Primary: Number of Participants With Otomicroscopic Signs of Otorrhea in Either Ear — 13; 27; 15; 23 participants
N/A N=33 Intraoperative Bleeding During Endoscopic Sinus Surgery
Blood Loss
Primary: Estimated Blood Loss — 78.5; 80.3 mL/h — p=0.937
N/A N=55 Nasotracheal Intubation Using Shikani Optical Stylet
Intubation; Difficult
Primary: Number of the Patients With Successful Nasotracheal Intubation — 35; 18 participants