N/A N=30 Implant Surface Decontamination in Peri-implantitis Treatment
Peri-implantitis · Periodontal Disease
Primary: Change in Total Bacterial Load on the Exposed Implant Surface — 2.77; 4.21 log (colony forming units/ml)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=57 The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositis
Peri-implant Mucositis
Primary: Global Probing Depth — 2.37; 2.64 mm — p=0.28
Phase 3 N=60 To Access the Effects of Mucositis in Adults With Dental Implants
Mucositis
Primary: Bleeding on Probing — 53.8; 52.3 Percentage of bleeding sites — p=0.05
N/A N=61 Periimplant Mucosa Dynamics Around Divergent and Concave Atlantis Abutment Transition Profiles
Dental Implant, Single-Tooth · Esthetics, Dental
Primary: Peri-Implant Mucosal Zenith Distance (in Millimeters) at the Concave/Divergent Abutment Sites — 9.860; 9.770; 9.684; 9.618 millimeters
Phase 2 N=46 Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis
Peri-implant Mucositis
Primary: Change in Interleukin 1 B at Base to 24 Hours — -1.075; 1.013 Micrograms per deciliter (ug/dl) — p=0.90
Phase 4 N=56 Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation
DENT IMPLANTS · LASER
Primary: Mean Probing Pocket Depth — 4.62; 4.45 millimeters
Phase 3 N=290 The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis
Peri-Implantitis
Primary: Absolute Change in Mean Probing Pocket Depth for Selected Target Implants — -1.69; -1.51 mm — p=0.1159
Phase 2 N=60 The Efficacy and Safety of Chlorhexidine Gluconate Chip (Periochip®) in Therapy of Symptoms in Patients With Peri-implantitis
Peri-implantitis
Primary: Change in Mean Probing Pocket Depth (PPD) for Selected Target Pocket — -2.13; -1.79 mm — p=0.1629
N/A N=31 Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase
Peri-Implantitis
Primary: Change in Probing Depth (PD) — -0.73; -1.36 mm
N/A N=36 Macrophage Markers in Periodontal and Peri-implant Health and Disease
Peri-Implantitis · Periodontitis
Primary: CD80 — 7340.34; 10854.71; 6448.43; 9874.8 arbitrary density units
Phase 4 N=49 Compare Anti-inflammatory Dentifrices
Gingivitis
Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05
N/A N=30 Influence of Mucosa Tissue Thickness on Marginal Bone Loss of Implants With Smooth Collars
Gingival Tissue
Primary: Radiographic Peri-implant Bone Change (Measured in Millimeters) Between Baseline and 12 Months Follow-up. — 0.78; 0.61 millimeters
N/A N=38 The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
Bone Loss · Implant Complication · Gingival Recession
Primary: Changes in Peri-implant Marginal Bone Level Between Baseline (Implant Placement) and 1 Year Follow up — 0.80; 0.32 millimeters — p=0.009
N/A N=24 Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis
Peri-Implantitis
Primary: Change in Periodontal Probing Depths (PD) — 1.85; 2.65 millimeters
Phase 4 N=20 Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
Tooth Loss · Peri-implant Mucosa Defect
Primary: Change in Buccal Peri-implant Mucosa Thickness Between Baseline and 16 Weeks After Surgery — 0.44; 0.05 millimeters
Phase 3 N=105 Clinical Study to Examine Brushing on Dental Implants
Gingival Diseases
Primary: Mombelli Plaque Index (mPI) for Natural Teeth — 1.96; 1.82 units on a scale — p=0.05
Phase 3 N=44 Antibiotic Study for Dental Implants
Periodontitis
Primary: Overall PD Reduction — 1.25; 0.66 mm
Phase 3 N=39 CATER: Comprehensive Alveolar and Tooth Esthetic Replacement
Dental Implant Failure Nos
Primary: Percent Change in Volume of Alveolar Ridge as Measured by 3D Intraoral Scanning — 15.5; 16.8 percentage of volume change
N/A N=12 Comparing Pro-Inflammatory Cytokines and Bone Metabolism Mediators Around Laser-Lok and Machined Transmucosal Abutments
Dental Implants
Primary: Difference in PICF Cytokine Levels (Log pg/ml) for Various Biomarkers, Specifically at Laser-Lok Abutment Sites and Machined Abutment Sites at 8 Weeks After Implant…
N/A N=145 Clinical Study Comparing Submerged Versus Trans-mucosal Healing of P.004 Implants in the Anterior Mandible and Maxilla
Jaw, Edentulous, Partially
Primary: Mean Change in Bone Level (Distance B) After 6 Months Compared to Baseline (=Surgery) — -0.32; -0.29 millimeters
N/A N=14 To Compare Free Gingival Grafts and Connective Tissue Grafts Around Implants With Lack of Keratinized Mucosa
Dental Implants · Alveolar Mucosa
Primary: The Increase in Keratinized Mucosa (in mm) Between the Two Grafts — 3.29; 1.29 mm
N/A N=22 Peri-Implant Healing Around Two Different Machined-Collar Designs After 25 Years of Function
Jaw, Edentulous
Primary: Comparison of Distance Between First Bone to Implant Contact Point (fBIC) and Microgap (MG), After 25 Years of Function, Between All B, All SW, and All SC Dental Implant…
Phase 4 N=39 Alternative Antibiotic Regime in the Treatment of GAgP
Generalized Aggressive Periodontitis · Aggressive Periodontitis
Primary: The Primary Outcome Variable Was Probing Depth. — 4.57; 4.18; 3.12; 2.91 mm — p=<0.01
N/A N=32 Induced Gingivitis & Intra-oral Imaging
Plaque Induced Gingivitis
Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale
N/A N=30 Marginal Bone and Soft Tissue Alterations After Use of OsseoSpeed EV Profile Implants
Alveolar Process Atrophy
Primary: Pink Esthetic Score (PES) at Temporary Crown Delivery. — 1; 1; 1; 1 score on a scale — p=0.0007
N/A N=32 Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Diabetes
Primary: Radiographic Bone Level — 2.69; 2.54 mm
N/A N=8 Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study
Peri-Implantitis
Primary: Percent Bacteria Biofilm — 32.78; 20.14; 11.8; 74.03 percentage of disc covered
N/A N=30 Plasma of Argon Cleaning on Implant Abutments: 5-year Results of a Randomized Clinical Trial
Endosseous Dental Implant Failure · Alveolar Bone Loss
Primary: Success Rate of the Implants and Prostheses (Participants). — 100; 100 percentage of participants — p=<0.05
Phase 4 N=38 Antimicrobial Agent for Reducing Bacteria in Aerosols and Oral Cavity
Dental Prophylaxis and Implant Surgery
Primary: Total Number of Detectable Plaque Bacteria Sampled 3 Days Post Implant Surgery — 7.63; 7.43 log(10) colony forming equivalents (CFE) — p=0.2965
N/A N=6 Customized Impressions in Dental Implants - Soft Tissues Changes
Soft Tissue
Primary: Changes in Soft Tissues Around Implant — 243.89 root mean square in µm