N/A N=67 Influence of IPV on GOR in Infants From 0 to 12 Months.
Gastro-oesophageal Reflux
Primary: Number of Refluxes — 0.48; 0.97 number of refluxes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=72 Interstitial Cystitis: Examination of the Central Autonomic Network
Interstitial Cystitis/Painful Bladder Syndrome · Myofascial Pelvic Pain
Primary: Total Score on Genitourinary Pain Index (GUPI) Scale — 24.4; 22.2; 2.35; 29.25 score on a scale
N/A N=96 Remote Ischemic Preconditioning in ad Hoc Percutaneous Coronary Interventions
Coronary Artery Disease
Primary: Delta Cardiac Troponin I (ΔcTnI) — 0.04; 0.19 ng/mL
N/A N=20 Effect of Intermittent Pedicle Clamping on Hepatocellular Injury During Liver Surgery
Hepatocellular Injury · Blood Loss
Primary: Hepatocellular Damage Reflected by Liver Fatty-acid Binding Protein (L-FABP) Levels — 9097; 11,688 ng*h/mL
Phase 3 N=40 Perioperative Iron for Colorectal Cancer (PICoC Study)
Cancer Colon
Primary: The Feasibility of Running the Study, to See if it Could be Run as a Large Multi-centre Study — 16; 18 participants
N/A N=101 Observational Study of Complications Related to Use of Peripherally Inserted Central Catheters
Adult Patients With Peripherally Inserted Central Catheters
Primary: Rate of PICC Line Occlusions — 37 percentage of enrolled subjects
Phase 3 N=1,135 Second Plecanatide Study In Irritable Bowel Syndrome With Constipation (IBS-C)
Irritable Bowel Syndrome Characterized by Constipation
Primary: Number of Overall Responders - ITT Population — 54; 81; 91 Participants
Phase 2 N=51 HIPEC for Peritoneal Carcinomatosis
Peritoneal Carcinomatosis · Colorectal Cancer · Appendiceal Cancer
Primary: Completeness of Cytoreduction
Phase 2 N=428 The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)
Irritable Bowel Syndrome Characterized by Constipation
Primary: Change From Baseline in Weekly CSBMs Frequency Over the 12-Week Treatment Period (mITT Population) — 1.28; 2.12; 2.74; 2.44 CSBMs per week
N/A N=144 Integrated Predictive Monitoring for Sepsis and Necrotizing Enterocolitis
Sepsis · Necrotising Enterocolitis Neonatal
Primary: Number of Participants With Sepsis or Necrotizing Enterocolitis — 20; 124 Participants
N/A N=64 Remote Ischemic PreConditioning Effect on Postsurgical Pain
Pain
Primary: Comparison of Pain Intensity and Unpleasantness Postoperatively — 4.82; 4.83; 4.05; 4.81 units on a scale
N/A N=30 Intra-Abdominal Hypertension in Neonatal Intensive Care Patients
Intra-Abdominal Hypertension
Primary: Intra-abdominal Pressure(IAP) Measurements in NICU Patients. — 1219 IAP measurements
Phase 3 N=951 The Plecanatide Chronic Idiopathic Constipation (CIC) Study
Chronic Idiopathic Constipation
Primary: Overall Responder 9/12 Weeks — 18.6; 16.8; 19.0; 10.7 % of Overall Responder 9/12 weeks
Phase 3 N=1,054 The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C)
Irritable Bowel Syndrome Characterized by Constipation
Primary: Number of Overall Responders - ITT Population — 63; 106; 103 Participants
N/A N=148 The Pediatric Intermed: A New Clinical Decision Making Tool
Inflammatory Bowel Disease
Primary: Pediatric INTERMED- Complexity Index — 24; 9.0; 4.0; 4.0 scores on a scale
Phase 2 N=21 Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling Pressures
Heart Failure
Primary: Characterize the Technical Feasibility of the Network Based IPC System — 72 percentage of days
N/A N=80 The Second-Generation MCCG for Upper Gastrointestinal Tract.
Capsule Endoscopy
Primary: Circumferential Visualization of the Z-line — 0; 5; 5; 7 Participants
N/A N=8 Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
Central Post Stroke Pain
Primary: Reduction in Spontaneous Pain Intensity After a Peripheral Nerve Block. — 6.5; 0.0 units on a scale
N/A N=10 Global Vascular Effects of Intermittent Pneumatic Compression-Pilot Study
Coronary Heart Disease
Primary: Brachial Flow Velocity — 21.0 cm/sec
N/A N=15 Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome
Irritable Bowel Syndrome · Abdominal Pain · Autonomic Nervous System Imbalance
Primary: Mean Change in IBS Symptom Severity From Baseline — 280; 320; 244; 316 score on a scale
Phase 3 N=1,337 12-Week Study of Plecanatide for CIC (The National CIC3 Study)
Chronic Idiopathic Constipation
Primary: Number of Durable Overall CSBM Responders, Mean Replacement Approach — 57; 88; 88 Participants
N/A N=31 EngagINg the COmmunity to Reduce Preterm Birth Via Adherence To an Individualized Prematurity Prevention Plan
Preterm Birth
Primary: Number of Eligible Participants Who Are Successfully Recruited and Attend at Least One Group Session — 20 Participants
Phase 3 N=1,346 12-Week Study of Plecanatide for CIC (The CIC3 Study)
Chronic Idiopathic Constipation
Primary: Number of Durable Overall CSBM Responders , Mean Replacement Approach — 46; 95; 86 Participants
N/A N=280 SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition
Postoperative Ileus · Anastomotic Leak
Primary: Number of Patients Developing Postoperative Ileus — 29; 37 Participants
N/A N=16 Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS
Interstitial Cystitis · Painful Bladder Syndrome
Primary: Primary Outcome Measure: Percentage of Subjects Improved Global Response Assessment Scale — 4; 3 Participants — p=0.317
N/A N=23 Treatment of Chronic Stroke With IpsiHand
Stroke
Primary: Change in Action Research Arm Test (ARAT) Score — 6.2 units on a scale — p=0.002
N/A N=9 Intermittent Pneumatic Compression to Improve Revascularization Outcome
Peripheral Arterial Disease
Primary: Walking Endurance — -14; 35 Meters
N/A N=33 Systematic Pediatric Assessment of Rome Criteria (SPARC)
Functional Gastrointestinal Disorders
Primary: Resolution of Symptoms From Initial Rome IV Diagnosis at 3 Months Using an Age-appropriate Rome IV Questionnaire. Number of Participants Who no Longer Meet Rome IV…
N/A N=212 Midlines and Thrombophlebitis
Catheter Infection · Catheter Thrombosis · Catheter Complications
Primary: Upper Extremity CR-UEVT — 7; 11 Participants
Phase 4 N=18 Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome
Irritable Bowel Syndrome
Primary: Colonic Compliance — 18.96; 16.86; 15.99; 15.75 mm Hg