Phase 2 N=80 Safety and Efficacy of AbobotulinumtoxinA for the Treatment of Platysmal Bands
Platysmal Bands
Primary: Responder Rate at Month 1 for a Single Dose of abobotulinumtoxinA Compared to Placebo — 3; 36 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=171 BOTOX® for the Treatment of Platysma Prominence
Platysma Prominence
Primary: Percentage of Participants With at Least 1-Grade Improvement at Day 14 as Rated by Investigator Using the Clinician Allergan Platysma Prominence Scale (C-APPS) — 12.0…
Phase 3 N=408 A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence
Platysma Prominence
Primary: Number of Participants With Adverse Events — 45; 47 Participants
N/A N=49 Prospective Pellevé™ Neck Wrinkle Study
Facial and Neck Rhytides
Primary: Change in Neck and Facial Wrinkles Using the Fitzpatrick Wrinkle Assessment — 74 percentage of participants
Phase 3 N=426 A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
Platysma Prominence
Primary: Number of Participants With Adverse Events — 43; 34 Participants
N/A N=50 Thermage CPT for Treatment of Facial and Neck Laxity
Skin Aging
Primary: Improvement in Laxity — 0.6; 1.0; 0.9; 1.3 units on a scale
N/A N=15 Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling
Skin Laxity
Primary: Percent Change From Baseline of Soft Tissue Surface Area — -0.18; -017 percent change
Phase 3 N=292 A Study To Assess the Safety of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Platysma Prominence
Platysma Prominence
Primary: Number of Participants With Adverse Events — 33; 74; 46; 26 Participants
N/A N=30 An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
Wrinkles in Decolletage
Primary: Percentage of Responders on the Galderma Décolletage Scale (GDS), as Assessed Live by the Treating Investigator, at Month 9 — 93.8; 78.6 percentage of Participants
N/A N=32 Lifting and Tightening of the Face and Neck Following an Increased Density Treatment
Skin Laxity
Primary: Improvement in Overall Lifting and Tightening of Skin — 48 percentage of participants improved
Phase 4 N=58 Sequential Treatment With BELKYRA® Then Juvéderm® VOLUMA™ With Lidocaine for Overall Improvement in Jawline Contour
Contour
Primary: Percentage of Participants Who Showed ≥ 1-point Jawline Improvement From Baseline on the Allergan Loss of Jawline Definition Scale (ALJDS), as Assessed by the…
N/A N=52 Lifting and Tightening of the Face in Subjects With Skin of Darker Color
Facial Skin Laxity
Primary: Change in Overall Lifting and Tightening of Treated Tissue
N/A N=99 A Study of Octave System for Improving Lines and Wrinkles of the Décolleté
Décolleté Wrinkles
Primary: Percentage of Treated Subjects With Improvement in Lines and Wrinkles of the Décolleté at Day 90 — 62.2 percentage of subjects
N/A N=2 The PREFORM Study: Rotational Fractional Resection for Submental Contouring
Skin Laxity · Lipodystrophy
Primary: Number of Participants Who Had at Least One Grade Improvement on the Submental Skin Laxity Scale — 2 Participants
N/A N=82 Renuvion APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region
Lax Skin
Primary: Day 180 Number of Participants With Improvement Measured By Independent Photographic Review — 6; 52 Participants — p=<0.0001
Phase 2 N=15 Pilot Evaluation of Platelet Rich Fibrin Matrix (PRFM) for the Correction of Nasolabial Folds
Nasolabial Folds
Primary: Difference in Wrinkle Assessment Score, Between Pre-treatment and 12 Weeks Post-treatment. — 1.13 units on a scale
N/A N=68 CONFORM: Rotational Fractional Resection for Submental Contouring
Skin Laxity · Lipodystrophy
Primary: Number of Participants With a Reduction of Submental Skin Area ≥ 20 mm^2 — 49 Participants
N/A N=148 Restylane Defyne for Correction of Chin Retrusion
Chin Retrusion
Primary: Percentage of Participants (Responders) With At Least 1-Point Improvement From Baseline on the GCRS, as Assessed by the Blinded Evaluator at Month 6 ([Baseline…
N/A N=60 Subcutaneous Fat Reduction in the Submental Area
Body Fat Disorder
Primary: Safety of CoolScupting in the Submental Area — 4 incidence of device- and/or procedure AE
N/A N=60 Open-label, Prospective Evaluation of the Ulthera® System for Lifting Submental (Under the Chin) and Neck Tissue in Chinese Patients
Mild to Moderate Skin Laxity Under the Chin · Mild to Moderate Skin Laxity on Neck
Primary: Mean Change From Baseline in Overall Lifting and Tightening of Submental (Under the Chin) and Neck Tissue Area at Day 90 Post-treatment — -14.4; -7.9; -22.3 square…
Phase 4 N=16 Submental Study (Sequential Treatment Approach)
Body Fat Disorder
Primary: The Proportion of Subjects Who Have at Least a 1-grade Improvement on the Clinician Reported Submental Fat Rating Scale (CR-SMFRS) at the Final Follow-up Visit When…
N/A N=72 Safety and Effectiveness Evaluation of the Device in Achieving Submental Lift
Skin Laxity
Primary: Tissue Lift at the Submental Area Measuring >/= 20 mm2 — 56.9 percentage of participants — p=0.05
N/A N=36 Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
Surgical Incision
Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale
N/A N=50 Effectiveness and Safety of the Octave System for Lifting the Eyebrow and Improving the Appearance of the Face and Neck
Eyebrow Lift · Improved Appearance of the Face and Neck
Primary: Percentage of Treated Subjects With Eyebrow Lift at Day 90 — 80.0; 67.5 percentage of subjects
Phase 3 N=235 MT10109L in the Treatment of Lateral Canthal Lines
Lateral Canthal Lines
Primary: The Percentage of Participants With a ≥ 2-grade Improvement From Baseline on the Facial Wrinkle Scale With Photonumeric Guide (FWS) According to INVESTIGATOR AND…
N/A N=74 CONtrolled Focal Fibrous Band Release Method Study
Cellulite
Primary: The Mean Change From Baseline to 3 Months in Cellulite Severity Scale (CSS) Score for Participants — 1.5 score on a scale — p=.0001
Phase 3 N=303 Treatment of Moderate to Severe Lateral Canthal Lines
Lateral Canthal Lines
Primary: Percentage of Subjects With a ≥ 2-grade Improvement From Baseline on the Lateral Canthal Line Investigator and Subject Assessments at Maximum Smile at One Month. — 106…
Phase 3 N=25 Assess Aesthetic Improvement With QM1114-DP in Subjects With Moderate to Severe Lateral Canthal Lines and Glabellar Lines
Glabellar Frown Lines · Canthal Lines
Primary: Responders Rate Using the Global Aesthetic Improvement Scale (GAIS) at Maximum Frown (Glabellar Lines) — 100 percentage of participants
N/A N=16 Jowl Improvement With Injectable Fillers
Jowls
Primary: Blinded Physician Jawline Rating Scale (JRS) Assessment on Scale of 0 to 4 at Baseline Versus 4 Weeks After Last Injection. — 2.214; 2.071; 1.857; 1.857 score on a scale…
N/A N=55 The Use of J-Plasma® for Dermal Resurfacing
Facial Wrinkles · Rhytides
Primary: Improvement in Fitzpatrick Wrinkle and Elastosis Scale (FWS) Score — 51 Participants