N/A N=31 The Effectiveness of Biofeedback for Individuals With Long-term Post-concussive Symptoms
Post-Concussion Syndrome
Primary: Change In SDNN — 43.; 21.87; 19.4 ms
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=3,063 Predicting Persistent Postconcussive Problems in Pediatrics (5P)
Concussions · PCS
Primary: Count of Children Who Have Persistent Post-concussive Symptoms (PCS) at One-month Follow-up. — 510; 291 Participants
Early Phase 1 N=26 The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome
Headache · Post-Concussion Syndrome
Primary: Immediate Change in Headache Scores With a Visual Analog Scale (VAS) — 5.6; NA; 3.5; NA units on a scale
Phase 2 N=79 Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
Post-concussive Symptoms · Traumatic Brain Injury
Primary: Post-Intervation Post-concussion Symptom Scores Using RPQ - Intent to Treat — 3.5; 5.1; 4.2; 3.5 units on a scale
Phase 4 N=25 Does Oral Micronized Progesterone Shorten Time of Symptoms From Concussion
Concussion
Primary: Time (in Days) That a Patient Reports Symptoms From Their Concussion. — 7.3; 4.5 Days Symptomatic — p=.42
N/A N=9 Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Concussion Injury of Cerebrum · Cranial Osteopathic Medicine
Primary: Change in Concussive Symptoms on the Post Concussion Symptom Scale — 9 units on a scale
N/A N=53 LED Therapy for the Treatment of Concussive Brain Injury
Brain Concussion
Primary: Mean Difference in Change in Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) Score at Baseline and 6 Weeks. — -0.9; -5.78; 3.52; -7.26 Units on a scale
N/A N=41 The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion
Concussion, Mild · Concussion, Brain · Concussion, Severe
Primary: Change in Vasoreactivity During Exercise at Baseline and 8-week Visits. — 0.031; 0.028 cm s-1 mmHg-1/mmHg CO2
N/A N=327 Movement Assessment for Concussion Management
Healthy Athlete
Primary: Impact ( Immediate Post-concussion Assessment and Cognitive Testing) Healthy Athlete — 86.33; 84.0; 90.73; 89.1436 score on Immediate post concussion scale — p=0.0003
N/A N=80 Use of Ibuprofen and Acetaminophen for Treatment of Acute Headache Post Concussion in Children
Concussion · Headache
Primary: Number of Headache Days — 4; 3; 3; 4 number of headache days
N/A N=120 Neurocognitive Evaluation of Mild Traumatic Brain Injury in the Hospitalized Pediatric Population
Mild Traumatic Brain Injury · Concussion
Primary: The Feasibility of Inpatient Bedside Neurocognitive Testing of Pediatric Patients With Minor Traumatic Brain Injury. — 120 participants
N/A N=27 Yoga and Female Concussion
Concussion Mild
Primary: Post Traumatic Growth — 41.7; 57.8; 40.4; 60.7 Score on a scale
Phase 2 N=71 mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms
Traumatic Brain Injury With Brief Loss of Consciousness · Post-Concussion Syndrome
Primary: Summary of Treatment-Emergent Adverse Events — 13; 5; 5; 3 Participants
N/A N=50 Pilot Clinical Investigation Evaluating the Safety and Performance of RGn550 in Treating Sportspeople Suffering From Acute Concussion Syndrome
Acute Concussion Syndrome
Primary: Incidence of RGn550's Adverse Device Effects (ADEs) — 10; 10 Participants
N/A N=113 Sub-Threshold Exercise Treatment for Adolescents With Sports Related Concussion
Brain Injury · Concussion
Primary: Time (in Days) to Recovery — 13; 17 Days
N/A N=50 Delivery of Digital Cognitive Behavioural Therapy Following Concussion
Concussion, Mild
Primary: Participant Compliance With HeadOn Program — 45; 5 Participants
N/A N=32 Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Concussion, Mild · Post-Concussion Symptoms · Sleep Problems
Primary: Performance on Multiple Sleep Latency Test (MSLT) — 6.67; 7.32; 6.73; 7.88 minutes
Phase 4 N=89 Prazosin for Post-Concussive Headaches
Post-Traumatic Headache
Primary: Change From Baseline in Headache Frequency — 16.4; 18.5; -9.2; -7.4 headaches per month
N/A N=62 High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions
Mild Concussion · Brain Concussion · Cerebral Concussion
Primary: Number of Days to Return to Full Unrestricted Athletic Participation — 11.0; 11.9 Days
Phase 2 N=89 Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin
Posttraumatic Headache · Combat Disorders · Post Concussion Syndrome
Primary: Headache Diary — -10.7; -6.9 headaches per month — p=0.034
N/A N=91 Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Traumatic Brain Injury · Post-Traumatic Stress Disorder
Primary: Change From Baseline in Community Reintegration for Injured Service Members at 2 Months — 40.22; 37.79 score on a scale
N/A N=50 Enhanced Problem-Solving Training
Brain Concussion
Primary: Brief Symptom Inventory-18 (BSI-18) Global Severity Index T-Score — 64.21; 65.26; 66.8; 61.35 units on a scale — p=.04
N/A N=64 Cognitive Rehabilitation in Post-COVID-19 Syndrome
Post-COVID-19 Syndrome
Primary: Recruitment Rate — 65 Participants
N/A N=66 Transcranial Electrical Stimulation for mTBI
Mild Traumatic Brain Injury (mTBI) · Post-traumatic Stress Disorder
Primary: Change in Abnormal Magnetoencephalography (MEG) Slow-Waves (1-4 Hz) Activity — 1.8; 0.2; 0 units on a scale — p=0.01
N/A N=72 Concussion Prevention in Female Soccer Athletes
Concussion, Mild · Concussion, Brain
Primary: Pre-season to Post-season DTI Percentage Change — -0.17; -1.27; 0.45; 2.83 percentage of change
N/A N=40 Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
Traumatic Brain Injury · Post Concussive Symptoms · Depression
Primary: Examiner Score — 0.617; 0.907; 0.865; 1.155 score on a scale
N/A N=84 Concussion Testing: A Novel Non-invasive Concussion Detection Device
Concussion
Primary: A Measure Assessing the Sensitivity and Specificity Rate Based on the Nautilus Neurowave Data — 77; 87 percentage of participants
Phase 2 N=21 Metoclopramide for Post-Traumatic Headache. A Pilot Study
Post-Traumatic Headache
Primary: Number of Participants With Sustained Headache Relief — 12 Participants
Phase 1 N=40 DHA For The Treatment of Pediatric Concussion Related to Sports Injury
Concussion · Mild Traumatic Brain Injury
Primary: Safety of Higher Dosage of DHA — 0; 1 Participants
Phase 2 N=12 Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers
Sports Concussion
Primary: Liver Function Testing (Aspartate Transaminase [AST]/Alanine Transaminase [ALT] Ratios) to Screen for Adverse Events. — 1.57; 1.24 AST/ALT ratio