Clinical Trial Search

Primary: Modified Manchester Scar Scale (MMSS) Score — 8; 11.5 score on a scale

Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale

Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale

Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline

Primary: Post-operative Scarring - Erythema — 1.67; 1.70; 1.50; 1.65 score on a scale — p=0.48

Primary: Subjective Cosmetic Result — 13; 26.5 units on a scale

Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale

Primary: The Measured Difference in POSAS and VAS Scores Between 7-day and 10-day Groups — 12.9; 16.1; 19.5; 20.3 score on a scale

Primary: Visual Analogue Scale (VAS) — 2.90; 3.29 score on a scale

Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…

Primary: Scar Evaluation at End of Treatment Period Comparing Treated to Standard of Care (Control) — 18.64; 50.52 score on a scale

Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019

Primary: Visual Analogue Scale (VAS) — 3.78; 5.58 Units on a scale

Primary: Physician Observer Scar Assessment Score at Week 24 — 0.0; -0.5; 0.8; -0.3 units on a scale — p=1.000

Primary: Physician Global Assessment Using Physician Overall Opinion Question of Patient and Observer Scar Assessment Scale (POSAS) — 4.00; 4.68; 4.61; 4.86 units on scale…

Primary: Expert Panel Scar Assessment Score at Week 12 — 36.6; 51.4 millimeter — p=<0.001

Primary: Expert Panel Scar Assessment Score at Week 12: Part B — 37.8; 42.1 millimeter — p=0.168

Primary: Photography- Independent Scar Assessment Panel

Primary: Change in Vectra Measured Length V1 (Month 0)-V2 (Month 3) for Original Group; Visit 3 (Month 6) to Visit 4 (Month 9) for Crossover Group — 0.10; 0.03 mm

Primary: Part B: Expert Panel Scar Assessment Score — -3.16; 0.18; 1.45; 2.91 millimeters

Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants

Primary: Healing Time — 78; 61 Days — p=0.094

Primary: Scar Quality at 6 Months Postoperative — 3.8; 2.6 units on a scale

Primary: Objective Erythema Assessment Using Clinical Grading Analog Scale — 0.8; 0.83; 0.75; 0.29 score on a scale

Primary: Total Morphine Milliequivalent (MME) Use Postoperatively After Cesarean Delivery — 52; 68 Morphine milligram equivalents

Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05

Primary: Number of Participants With Intraoperative Acquired Pressure Injuries (IAPI) — 13; 14 Participants

Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 8; 0 Participants

Primary: Graft Size Change — 10 percent change in graft

Primary: Wound QOL Survey Score Over Time — 1.14; 0.94; 0.77; 0.66 score on a scale