N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=81 Cognitive Training for PTSD
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale - Reexperiencing — 2.6; 2.96 score on a scale
N/A N=64 Neurobiological Similarities of Tinnitus and PTSD
Posttraumatic Stress Disorder · Tinnitus
Primary: Resting-State Functional MRI — 0.55; 0.35; 0.29; 0.59 Z-Score — p=0.01
N/A N=55 Cognitive-Behavioral Therapy for Veterans With TBI
Insomnia · Traumatic Brain Injury
Primary: Change in Insomnia Severity — 8.833; 7.810; 9.625; 8.364 score on a scale
N/A N=110 Cognition and Psychotherapy in PTSD
Posttraumatic Stress Disorder (PTSD)
Primary: Change in PTSD Checklist (PCL-5) — 9.25; 11.94; 15.91 change in units on a scale
N/A N=98 Study of PTSD in Military Veterans Who Have Suffered Traumatic Brain Injuries
PTSD · TBI
Primary: Change in Diagnostic and Statistical Manual of Mental Disorders IV Clinician-Administered PTSD Scale DSM IV-(CAPS) — 73.13 units on a scale
N/A N=193 Cognitive-Behavior Therapy for Posttraumatic Headache
Post-traumatic Headache · PTSD
Primary: Headache-related Disability Scores on the Headache Impact Test 6 (HIT-6) — 66.1; 66.1; 65.2; 61.9 score on a scale — p=<0.001
N/A N=10 Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD
Stress Disorders, Post-Traumatic · Tinnitus
Primary: Change in Score on Clinician Administered PTSD Scale for the DSM-5 (CAPS-5) — 33.10; 16.13 score on a scale — p=0.01
N/A N=139 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
Stress Disorder - Post-traumatic (Acute)
Primary: Severity of PTSD Symptoms — 43.4; 43.9 CAPS total Score at treatment end — p=0.927
N/A N=50 Enhanced Problem-Solving Training
Brain Concussion
Primary: Brief Symptom Inventory-18 (BSI-18) Global Severity Index T-Score — 64.21; 65.26; 66.8; 61.35 units on a scale — p=.04
N/A N=87 Neurofeedback Impact on Veterans With mTBI
Concussion · mTBI · Post-Concussive Symptoms
Primary: Headache Impact Test (HIT-6) — 53.2; 61.4; 49.2; 60.9 score on a scale — p=<.0001
N/A N=26 Novel EEG Coherence Biomarkers for PTSD Assessment
PTSD
Primary: Coherence — 0.28; 0.27; 0.27 Coherence — p=0.01
Phase 1 N=34 Imaging the Neuroimmune System in PTSD
Post Traumatic Stress Disorder
Primary: Baseline TSPO Availability — 5.11; 4.75; 5.07; 4.38 mL/cm3
N/A N=69 Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD
PTSD
Primary: Change in Clinician-Administered PTSD Scale for DSM-5 — 38.39; 35.67; 27.15; 29.31 score on a scale — p=0.4154
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=30 Adjunctive Pregnenolone in Veterans With Mild TBI
Traumatic Brain Injury
Primary: Brief Assessment of Cognition in Affective Disorders (BAC-A) — 0.61; 0.80 units on a scale
N/A N=124 Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
Post-traumatic Stress Disorder
Primary: Weekly Number of Nightmares — 3.95; 3.88; 3.28; 3.47 weekly nightmares
N/A N=46 Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
Post Traumatic Stress Disorder · Mild Traumatic Brain Injury, Concussion
Primary: Change in Performance on Neurocognitive Measure of Attention and Executive Function Post GOALS Intervention vs EDU Control Training — -0.03; -0.39 z score — p=<0.01
N/A N=61 Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder
Primary: Change (From Intake to Post-therapy) in Resting-state Functional Connectivity Between Posterior Cingulate Cortex (PCC) and Dorsolateral Prefrontal Cortex (dlPFC)…
N/A N=25 DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Stress Disorders, Post-Traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 63.08; 61.71; 42.83; 51.65 units on a scale
Phase 2 N=53 Neuroactive Steroids and Traumatic Brain Injury (TBI) in OEF/OIF Veterans
Brain Injuries, Traumatic
Primary: CAPS (Cluster D Symptoms) - PRIMARY BEHAVIORAL OUTCOME MEASURE — 13.88; 12.89; 11.23; 10.89 Score
N/A N=91 Cortisol Suppression and Startle Responses in Posttraumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder
Primary: Mean Baseline Startle Magnitude During Fear Conditioning — 48.401; 56.595; 115.778; 57.684 microvolts
N/A N=31 Information Processing Modification in PTSD (Oct. 18)
Stress Disorders, Post-traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 57.14; 61.33; 52.21; 53.78 units on a scale
Phase 4 N=89 Prazosin for Post-Concussive Headaches
Post-Traumatic Headache
Primary: Change From Baseline in Headache Frequency — 16.4; 18.5; -9.2; -7.4 headaches per month
Phase 3 N=36 Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
Combat Disorders · Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (Pre & Posttreatment) — 30.0; 53.6 units on a scale
Phase 3 N=80 Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Stress Disorders, Post-Traumatic
Primary: Change Scores for Criteria D Items on the CAPS Structured Clinical Interview — -1.20; -6.27 units on a scale — p=.27
N/A N=61 Neuroimaging the Impact of Treatment on Neural Substrates of Trust in Post-Traumatic Stress Disorder (PTSD)
Stress Disorders, Post Traumatic · Trust
Primary: Continuous Whole Brain Imaging With Standard Imaging Parameters for Each Functional Magnetic Resonance Imaging (fMRI) Scan
Phase 2 N=17 Prolonged Exposure and Oxytocin
PTSD
Primary: PTSD Symptom Severity — 13.00; 17.71 scores on a scale
N/A N=30 Top-Down Executive Control in Traumatic Brain Injury (TBI), PTSD and Combined
PTSD · TBI (Traumatic Brain Injury)
Primary: Functional Magnetic Resonance Imaging (fMRI) Correlation — .21; .19; .36 r-value
Phase 3 N=56 Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder
PostTraumatic Stress Disorder
Primary: Level of Interleukin-6 (IL6) — 0.88; 0.84; 1.77; 2.11 pg/ml