Phase 3 N=2,464 High Dose Folic Acid Supplementation Throughout Pregnancy for Preeclampsia Prevention
Pregnancy Complications · Preeclampsia
Primary: Preeclampsia — 169; 156 Participants — p=0.37
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=299 Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
Emotional Disturbances · Depression · Pregnancy Late
Primary: Change in Self-reported Healthy Lifestyle Beliefs Timepoint 0 to Timepoint 3 — 59.044; 59.349; 64.972; 64.234 units on a scale — p=<0.001
N/A N=50 The Health Check-Up for Expectant Moms
HIV
Primary: CIAS (Computerized Intervention Authoring Software) Satisfaction Measure Scores to Assess the Feasibility and Acceptability of the Computer and HCEM Software — 4.8; 6.6…
Phase 3 N=10,154 Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia
Primary: Composite of Pregnancy-associated Hypertension and Serious Adverse Outcomes in the Mother or Fetus or Neonate — 305; 285 Participants — p=0.42
N/A N=16 Acute Exercise Effects in Obese Pregnancy
Pregnancy Complications · Obesity · Pre-Eclampsia
Primary: Oral Glucose Insulin Sensitivity (OGIS) Index — 405.0; 426.0; 418.9 uU/mL
N/A N=224 Nudge to Drive Transitions of Care
Preeclampsia · Preeclampsia Severe · Gestational Hypertension
Primary: Number of Patients With Documented Counseling on Transitions of Care — 38; 28 Participants
N/A N=360 Participate While Pregnant Survey
Pregnancy
Primary: Willingness to Participate in Research While Pregnant — 319; 39; 288; 70 Participants
N/A N=360 Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Maternal Obesity · Gestational Weight Gain · Obstetric Complications
Primary: Cesarean Section
N/A N=11,976 Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)
Premature Birth
Primary: Incidence of Preterm Birth — 668; 754 Participants — p=0.012
N/A N=51 Sedentary Behavior Reduction in Pregnancy Intervention Study
Pregnancy Complications · Sedentary Behavior
Primary: Sedentary Time — 10.42; 10.52; 9.62; 10.38 total hours/day — p=<0.05
N/A N=118 Weight Management for Improved Pregnancy Outcomes
Obesity · Pregnancy
Primary: Maternal Weight Change — 1.2; -2.6 kg
N/A N=151 Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
Cardiovascular Disease · Preeclampsia · Hypertension
Primary: Eating Habits Confidence Survey — 4.2; 4.5 units on a scale
Phase 3 N=321 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Preterm Birth
Primary: Newborn Respiratory Distress Syndrome (RDS) — 44; 18 Twins
Phase 2 N=482 Reducing Preterm Births in Underserved Pregnant Women
Preterm Birth · Low Birth Weight <2500 Grams · Verylow Birthweight <1500 Grams
Primary: Birthweight — 40; 26 participants
N/A N=24 Pregnancy Intervention With a Closed-Loop System (PICLS) Study
Type 1 Diabetes Mellitus · Pregnancy in Diabetes
Primary: Number of Episodes of Severe Hypoglycemia — 0; 0 Number of Episodes
N/A N=343 Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
Hypertension, Pregnancy-Induced · Postpartum Preeclampsia · Hypertension; Maternal
Primary: Proportion of Participants With Recorded Blood Pressure Values in Office — 43; 44; 49; 56 Participants
N/A N=29 Prenatal Mindfulness & Hypertension Study
Hypertension in Pregnancy
Primary: Retention and Adherence — 12; 11 Participants
Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
N/A N=176 Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy
Sexually Transmitted Infection · Alcohol Use Complicating the Puerperium · Alcohol Use Complicating Pregnancy, Unspecified Trimester
Primary: Unprotected Sexual Occasions (USOs) — 27.73; 41.50; 8.68; 14.70 USOs per participant — p=0.2964
N/A N=117 Happy Mother - Healthy Baby: Supplement Study on Biological Processes Underlying Anxiety During Pregnancy
Anxiety
Primary: Peripheral Markers of Inflammation — 17.09; 20.22; 14.79; 11.78 pg/ml
N/A N=95 Early Screening and Treatment of Women With Prediabetes in Pregnancy
Diabetes · Pregnancy
Primary: Number of Patients With a Diagnosis of Gestational Diabetes at 26 Weeks Gestation. — 19; 23 Participants — p=0.32
Phase 3 N=220 Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida
Pre-Eclampsia · Hypertension in Pregnancy · Obesity
Primary: Number of Participants With Preeclampsia Diagnosis With Severe Features Based on Clinician Diagnosis — 37; 41 Participants
N/A N=220 Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk
Maternal Behavior · Postpartum Depression
Primary: Emergency Department (ED) Visits and Readmissions — 18; 21 Postpartum Hospital Use
Phase 4 N=2,408 Chronic Hypertension and Pregnancy (CHAP) Project
Hypertension
Primary: Composite Adverse Perinatal Outcome — 353; 427; 272; 336 Participants — p=<0.001
N/A N=320 Improving Women's Health Through Coordinated Postpartum Planning
Maternal Death · Maternal Morbidity
Primary: Number of Participants Attending a Comprehensive Postpartum Visit — 84; 89 Participants
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
N/A N=32 Centering Pregnancy Care + Yoga for Diverse Pregnant Women
Pregnancy
Primary: Feasibility of Retention/ Adherence — 15; 17 Participants
N/A N=150 Psychological Impact of Pregnancy of Unknown Location
Pregnancy of Unknown Location · Ectopic Pregnancy · Anxiety
Primary: Psychological Morbidity — 10; 10; 5; 5 score on a scale
N/A N=103 Twinrix Pregnancy Registry
Hepatitis
Primary: Number of Outcomes From Pregnancies With Reported Exposure Within 28 Days of Last Menstrual Period — 0; 0; 0; 0 Pregnancy Outcomes
Phase 2 N=208 Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia
Pre-Eclampsia
Primary: Change in Pulsatility Index (PI) — -0.56; -0.53; -0.43; -0.88 ratio