N/A N=43 Treatment of Prepubertal Labial Adhesions
Prepubertal Labial Adhesions
Primary: Complete Resolution of Labial Adhesion. — 21; 22 Participants — p=0.206
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Evaluation of the Use of the Renuvion APR System in the Labia
Labia Enlarged · Labium; Hypertrophy
Primary: Evaluation of Change Between Baseline and Follow-up Images as Determined by a Masked, Qualitative Assessment of Photographs at 90-days and 180-days Post-treatment…
Phase 4 N=54 Unicirc Adolescent 12-15 Year Old Boys
Circumcision, Male
Primary: Intraoperative Duration — 9.5 minutes
Phase 3 N=50 The Adrenal Contribution to Androgen Production in Girls During Puberty
Development
Primary: 17-hydroxyprogesterone Response to ACTH — 2.4; 3.7; 3.1; 2.9 ng/mL
N/A N=318 Rapidly Absorbing Polyglactin 910 Versus Poliglecaprone 25 for Laceration Repair
Dyspareunia · Perineal Tear · Sutured Laceration
Primary: Rates of Dyspareunia — 3.6; 3.49 units on a scale — p=0.16
Phase 4 N=61 Efficacity Assessment of PREVADH® in Adhesion Prevention in Gynaecologic Surgery
Uterine Fibroids · Fertility Disorders
Primary: Number of Patients With Adhesions to Uterine Scars — 12; 24 participants
Early Phase 1 N=6 Investigation of Female Reproductive Hormone Dynamics During Adolescence
Menstruation Disturbances
Primary: Ovulation in Cycle 2 — 3; 2 Participants
Phase 4 N=59 Vaginal Estrogen on Postpartum Atrophy, Perineal Pain, and Sexual Function
Vaginal Atrophy
Primary: Vulvar Assessment Scale (VUAS) — 0.10; 0.20 score on a scale
N/A N=8 Skin Incision Adhesive in Pediatrics
Wounds
Primary: Number of Participants With Wound Closure — 8 participants
N/A N=110 Phase 4 Field Trial of the Unicirc Instrument With Tissue Adhesive
Male Circumcision
Primary: Time for Procedure — 9.0 Min
N/A N=20 Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure
Ovarian Failure, Premature
Primary: Estradiol — 53; 14; 12 pg/mL
N/A N=11 Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus
Skin Laxity
Primary: General Skin Appearance of Mons Pubis and Labia — 3; 4; 1 Participants
Phase 4 N=30 Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor
Pelvic Organ Prolapse · Menopause
Primary: Vaginal Wall Composition: Epithelium (Intention to Treat) — 413.9; 314.1 microns — p=0.21
N/A N=23 PREvention of Intrauterine Adhesion After Hysteroscopic Surgery With Novel deGradable Film
Intrauterine Adhesion
Primary: Safety (Adverse Events) — 0 device related adverse event
Phase 3 N=37 Efficacy and Safety Study of Pamoate of Triptorelin in Children With Precocious Puberty
Precocious Puberty
Primary: Number of Participants With a GnRH-stimulated LH Level ≤3 IU/L — 31; 6; 31; 3 participants
Phase 4 N=96 Postpartum Etonogestrel Implant for Adolescents
Adolescence · Contraception · Postpartum
Primary: Continuation at 1 Year — 21; 30 participants
Phase 4 N=199 Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen
Pelvic Organ Prolapse · Urogenital Prolapse · Vaginal Vault Prolapse
Primary: Surgical "Failure" Defined by (i) Anatomic Assessment of Prolapse, (ii) Presence of Bulge Symptoms, and/or (Iii) Retreatment of Prolapse — 18; 8 Participants
Phase 3 N=36 Histrelin Subcutaneous Implant in Children With Central Precocious Puberty
Central Precocious Puberty
Primary: Luteinizing Hormone (LH) — 0.88; 0.53; 0.07; 0.50 MIU/ML
N/A N=37 Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation
Pelvic Floor Disorders
Primary: Patient Reported Ease of Dilation — 6.6; 7.4; 8.0 units on a scale
Phase 3 N=81 Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents
Contraceptive Usage
Primary: Number of Participants With Contraceptive Implant Continuation at Six Months Postpartum — 15; 7 Participants
N/A N=93 Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
Asherman's Syndrome
Primary: Number of Participants With Pregnancy in Loop-shaped Intrauterine Device Group and Intrauterine Balloon Group — 12; 22 participants — p=0.009
Phase 4 N=20 Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy Menstrual Bleeding
Menorrhagia
Primary: Maximum Concentrations Level (Cmax) — 6.9967; 10.9868 μg/mL
Phase 3 N=35 Effects of Triptorelin Pamoate in Children With Precocious Puberty - Follow up Study
Precocious Puberty
Primary: Percentage of Children With a Stabilisation or Regression of Tanner Pubertal Stage at the End of the Study (Final Visit), Compared to Pretreatment (Month -6) and…
N/A N=222 Human Repeat Insult Patch Test to Evaluate Personal Lubricants
Erythema · Edema
Primary: Number of Patients That Showed Sensitization Reaction to the Test Material at Challenge — 0 Participants
Phase 4 N=104 The Health Influences of Puberty (HIP) Study
Obesity · Insulin Resistance · Gonadal Dysfunction
Primary: Insulin Sensitivity — 8.559; 3.425; 3.756; 2.985 x10-4/min-1/mIU/mL
N/A N=49 Vaginally Assisted Laparoscopic Hysteropexy Versus Vaginal Hysterectomy
Pelvic Organ Prolapse
Primary: Number of Participants With Recurrence of Pelvic Organ Prolapse — 0; 0 Participants
Phase 2 N=141 Comparison of Different Doses of Oestrogen Therapy for Preventing Intrauterine Adhesion
Asherman Syndrome
Primary: the AFS Score at Second-look Hysteroscopy — 1.6; 1.9 units on a scale — p=>0.05
Phase 2 N=54 Topical Anesthetic Use In Pessary Management
Pain
Primary: VAS Score at the Time of Pessary Removal Adjusting for Baseline Pain — 1.76; 3.81 Centimeters — p=.02
N/A N=65 Engaging Families to Improve the Care of Patients With Hypospadias
Hypospadias
Primary: Percent of Eligible Parents Screened (Feasibility) — 90.5 percentage of parents recruited
N/A N=47 Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia
Vulvar Intraepithelial Neoplasia (VIN)
Primary: Number of Participants With Recurrence of Dysplasia — 5; 8 Participants