Phase 1 N=16 Computer Vision System for the Blind Veteran
Blindness
Primary: Frequency of Device Failures Per Attempt to Complete a Navigation Course — 4.1; 2 number of device failures per attempt
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=18 SmartHMD for Improved Mobility
Low Vision · Orientation · Mobility Limitation
Primary: Time-to-Complete — 14.75; 32.75; 148.17; 17.3 Seconds
N/A N=49 Collision Warning Device for Blind and Visually Impaired
Hemianopia · Hemianopsia · Peripheral Visual Field Defect
Primary: Number of Collision Incidents (All Contacts) — 13.79; 9.26 Rate (contacts per 100 hazards per hour) — p=< 0.001
Phase 3 N=241 Improving Function in Age-Related Macular Degeneration
Age-Related Macular Degeneration
Primary: Targeted Vision Function (TVF) — 2.18; 2.14 units on a scale — p=.47
N/A N=115 BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
Glaucoma · Macular Degeneration · Glaucoma Suspect
Primary: Visual Impairment Measured by Visual Functioning Test — 80.6; 74.2; 81.1 score on a scale — p=0.011
N/A N=76 New Visual Acuity and Crowding Tests for Better Detection of Amblyopia
Amblyopia
Primary: Visual Acuity (LogMAR) — 0.004; 0.551; 0.320; 0.005 logMAR
N/A N=79 Patient Perception of Visual Distortions
Cataract · Astigmatism
Primary: Visual Distortion Symptoms — 0.89; 0.38; 0.64; 0.38 rating of visual distortion symptoms
N/A N=22 Optical Head-Mounted Display Technology for Low Vision Rehabilitation
Retinal Dystrophies · Healthy
Primary: Change in the Planimetric Area of Goldmann Visual Field With the Use of Head-mounted Display Technology Compared to Baseline (Measured in Degrees Squared) — 563.08…
N/A N=26 Environmental Localization Mapping and Guidance for Visual Prosthesis Users
Retinitis Pigmentosa · Visual Impairment · Visual Prosthesis
Primary: Duration of Time to Complete Navigational Tasks as Assessed by the Mean Duration of Travel in Seconds Normalized by the Nominal Path Distance in Meters — 14.54; 14.09…
N/A N=48 Visual Restoration for Hemianopia
Stroke Induced Vision Loss · Hemianopia · Quadrantanopia
Primary: 24-2 Humphrey PMD Change From Baseline to 6-month Post-training Timepoint — 0.84; 0.10; 0.58; 0.12 decibels
N/A N=30 Multiplexing Prism Fitting for Field Expansion of Monocular Vision
One Eye Blindness · Blind Left Eye · Blind Right Eye
Primary: Gain in Visual Field With the Multiplexing Prism — 24 degrees
N/A N=120 DigiVis: Self-testing Vision App for Telephone Consultations
Visual Impairment · Amblyopia Suspect
Primary: Mean Bias Between the Difference Between DigiVis and Standard Visual Assessment Compared to the Mean of DigiVis and Standard Visual Assessment — 0.112; 0.100 logMAR
N/A N=100 Evaluation of a Night Spectacle Correction Concerning an Improvement of Mesopic Vision Quality
Myopia-Night Blindness
Primary: Night Myopia — -0.30; -0.32 D
N/A N=100 Visual Function During Gait in Parkinson's Disease: Impact of Cognition and Response to Visual Cues
Parkinson's Disease
Primary: Visual Sampling Parameter: Saccade Frequency During Gait — 0.48; 0.76; 0.67; 0.77 Saccade frequency (sacc/sec)
N/A N=318 Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening
Amblyopia · Strabismus
Primary: Detection of Amblyopia and Strabismus in Children Ages 2-5 Using Automated Pediatric Vision Scanner Device — 6; 249; 0; 45 Participants
N/A N=13 Understanding Visual Confusion Using Stereoscopic Displays
Diplopia · Binocular Vision Suppression · Binocular; Fusion, With Defective Stereopsis
Primary: Percentage of Total Viewing Time That Peripheral Target is Perceived — 73.56; 59.64; 87.81 Percentage of Time — p=<0.01
Phase 2 N=323 Low Vision Intervention Trial II (LOVIT II)
Central Vision Loss From Macular Diseases
Primary: Comparison of Changes in Visual Reading Ability From Baseline to Four Months Later Measured With 48 Item VA Low Vision Visual Functioning Questionnaire — 1.29; 0.95…
Phase 2 N=45 Trial of L-DOPA as a Treatment to Improve Vision in Albinism
Albinism
Primary: Improved Vision — 0.67; 0.55; 0.53 logMAR
N/A N=37 Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
Stroke · Neurologic Disorder · Traumatic Brain Injury
Primary: Bells Test — 14.2; 18.3; 19.3; 27.1 Number of items correct — p=0.1779
N/A N=21 Visual Activity Evoked by Infrared in Humans After Dark Adaptation
Age Related Macular Degeneration · Retinitis Pigmentosa · Congenital Stationary Night Blindness
Primary: Visual Perception to Infrared: Mean Minimal Intensity (uW) at Which Participants Could See IR Between 900 - 1400 nm. — 0.671770454; 0.809204; 0.205456012; 0.222247 uW…
N/A N=11 Evaluating and Improving Functional Driving Vision of Patients With Astigmatism
Astigmatism
Primary: Tactical Composite Score — -1.73; 0.19; 1.54 Z score
N/A N=6 VR System for Cross-modal Rehabilitation of Hemianopia
Hemianopia, Homonymous · Hemianopsia, Homonymous
Primary: Humphrey Visual Field Perimetry — 108; 1272 visual angle degrees^2
N/A N=5 Multisensory Rehabilitation of Hemianopia
Hemianopia
Primary: Number of Points Detected at Multiple Locations — 14.0; 94.9; 63.6; 95.4 Number of points
N/A N=20 A Novel Method for Capturing the Visual Evoked Potential During Spine Surgery Under Total Intravenous Anesthesia
Evoked Potentials, Visual
Primary: Number of Participants With Presence of VEPs — 18 Participants
N/A N=4 Visuomotor Rehabilitation Training for Manual Task Deficits From Macular Scotomas
Scotoma, Central · Central Visual Impairment
Primary: Improvement in Eye-hand Coordination — 42.8; 45.4; 30.4; 71.0 Percentage
N/A N=161 How Has Glaucoma Affected Your Quality of Life?
Glaucoma · Quality of Life
Primary: Quality of Life With NEI VFQ-25 — 82.9; 82.7; 82.8; 83.0 units on a scale
Phase 2 N=42 Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Down Syndrome · Refractive Errors
Primary: Distance Visual Acuity — 0.41; 0.41; 0.40; 0.43 logMAR — p=0.92
N/A N=61 Beacon Sensors and Telerehabilitation for Low Vision
Low Vision
Primary: Activity Inventory — 0.44; 0.43 logit — p=0.73
N/A N=6 The Perceptual Experience of Argus II Users
Retinitis Pigmentosa
Primary: Number of Phosphenes Perceived — 1.09; 1.43; 1.46; 1.41 number of phosphenes — p=0.002
N/A N=4 Virtual Reality Mobility Training System for Veterans With Vision Loss
Blindness
Primary: Accuracy in Judging Direction of Traffic at Traffic Intersection — 0 participants