N/A N=20 Internal Jugular Vein Compression Collar for Novel Symptomatic Treatment of Venous Pulsatile Tinnitus
Pulsatile Tinnitus
Primary: Change From Baseline in Pulsatile Tinnitus Symptom Intensity — 3 units on a scale — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=22 Cochlear Promontory Stimulation for Treatment of Tinnitus
Tinnitus
Primary: Change in Short Term Relief of Tinnitus as Measured by the Tinnitus Handicap Inventory — -31 score on a scale
N/A N=100 Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts
Tinnitus
Primary: Change in Objective Tinnitus Loudness — -6.1; -9.5; -10.2; -11.0 decibels sensation level (dB SL)
N/A N=10 Somatosensory Tinnitus Study
Tinnitus
Primary: Tinnitus Functional Index — 57.7; 39.6 score on a scale
N/A N=5 rTMS Bimodal Treatment For Tinnitus: A Pilot Study
Tinnitus
Primary: Adverse Events — 0 participants
N/A N=39 Effect of rTMS on Resting State Brain Activity in Tinnitus
Tinnitus
Primary: Change From Baseline on the Analogue Rating of Tinnitus Awareness. — -4.08; -4.70; -9.82; -9.89 units on a scale — p=.04
Phase 2 N=12 rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study
Tinnitus
Primary: Average Change (Baseline-End of Treatment) Tinnitus Handicap Inventory (THI) — 10.7 units on a scale
N/A N=5 Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus
Tinnitus
Primary: Change in PET Asymmetry Index — 1.2 ratio
N/A N=290 Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial
Tinnitus
Primary: Tinnitus Questionnaire (TQ, Goebel and Hiller 1998) Total Score Change From Baseline to End of Treatment — 13.6; 3.7 absolute TF-score change
N/A N=64 Neurobiological Similarities of Tinnitus and PTSD
Posttraumatic Stress Disorder · Tinnitus
Primary: Resting-State Functional MRI — 0.55; 0.35; 0.29; 0.59 Z-Score — p=0.01
N/A N=21 Auditory-somatosensory Stimulation to Alleviate Tinnitus
Tinnitus
Primary: Change in TFI (Tinnitus Functional Index) After Treatment or Sham Compared to Baseline — -10.08; -5.40; 0.95; -4.34 units on a scale — p=<0.05
Phase 2 N=70 Transcranial Magnetic Stimulation for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) Score — -13.8; -2.9 units on TFI scale; change from baseline
N/A N=108 Cognitive Speed as an Objective Measure of Tinnitus
Tinnitus
Primary: Brain Speed Test — -0.09 z-score
Phase 4 N=40 Nitrous Oxide Treatment for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) Score — -1.8; -2.5 score on a scale
N/A N=181 Progressive Intervention Program for Tinnitus Management
Hearing Loss · Tinnitus
Primary: THI (Tinnitus Handicap Inventory) — 37.0; 43.0; 33.0; 40.0 scores on a scale
Phase 4 N=78 Treatment of Tinnitus With Migraine Medications
Tinnitus, Subjective · Tinnitus
Primary: Tinnitus Functional Index (TFI) — -12.1; -12.4; -6.0 scores on a scale
N/A N=30 Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Tinnitus
Primary: Number of Participants With Serious Adverse Events — 1; 2 participants
N/A N=10 Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD
Stress Disorders, Post-Traumatic · Tinnitus
Primary: Change in Score on Clinician Administered PTSD Scale for the DSM-5 (CAPS-5) — 33.10; 16.13 score on a scale — p=0.01
N/A N=56 Evaluation of Auditory Mirror-therapy for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) — -10.7; -10.9 units on a scale — p=<0.01
N/A N=205 Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
Tinnitus
Primary: Tinnitus Functional Index — 69.9; 68.2; 47.8; 66.8 units on a scale — p=<.0001
N/A N=65 Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus
Tinnitus · Hearing Aids · Normal Hearing
Primary: Tinnitus Functional Index Change — 53.31; 44.10; 64.93 units on a scale
Phase 2 N=10 An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus
Tinnitus
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAE) — 1 Participants
Phase 2 N=34 Collaborative Tinnitus Research at Washington University
Subjective Tinnitus
Primary: Change in THI (Tinnitus Handicap Inventory) — -5; -6; -10; -6 units on a scale — p=0.944
N/A N=300 Multi-Site Evaluation of Progressive Tinnitus Management
Tinnitus
Primary: Tinnitus Functional Index Change Score — -5.71; .8 units on a scale
Phase 3 N=38 A Trial of Magnesium Dependent Tinnitus
Tinnitus
Primary: Tinnitus Distress Rating — 5.71; 5.82; 5.36; 5.46 units on a scale
N/A N=6 Magnetic Resonance Imaging Evaluation of Inner Ear Pathology Using Intra-Tympanic Contrast Agent
Meniere's Disease
Primary: Vestibular "Endolymphatic Hydrops (EH)" — 0; 4; 2 participants
Phase 2 N=43 OTO-313 in Subjects With Subjective Tinnitus
Tinnitus, Subjective
Primary: Audiometry - Pure Tone Average Done Over 1000, 2000 and 4000 Hertz (HZ) — -0.3; 0.71; -0.8; 0.3 decibels
N/A N=20 Resting-State Neural Connectivity in Patients With Subjective Tinnitus Without Bother
Tinnitus
Primary: Number of Participants With Changes in Blood Oxygen Level as Measured by Functional Connectivity MRI — 18 participants — p=<0.01
N/A N=97 Mahana Tinnitus Pilot
Tinnitus
Primary: Mean Change in TFI Score From Baseline to Week 6 — -20.50 score on a scale
Phase 3 N=100 Evaluation of the CR Neuromodulation Treatment for Tinnitus
Tinnitus
Primary: Tinnitus Handicap Questionnaire (THQ) — 3.75; 4.02 units on a scale