Phase 3 N=40 Impact of TheraWorx Foam on Symptom Relief in Thumb Arthritis
Arthritis
Primary: Numeric Pain Rating Scale — 1.7; 2.4; 3.2 units on a scale — p=0.6
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=120 Osteoarthritis Knee Pain Relief Study of 0.25% 920-CGS-200
Osteoarthritis, Knee
Primary: Percentage of Subjects With 50% or Greater Pain Score Reduction From Baseline to 24 Hours After First Dose of Study Drug Treatment. — 27.03; 20.0; 23.08; 20.0 percentage…
Phase 2 N=53 Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
Breast Cancer · Joint Pain
Primary: Change in WOMAC Score — 24.9 Score on a scale — p=0.004
N/A N=25 MONOVISC for Hip Joint Pain Relief Due to Osteoarthritis
Osteoarthritis, Hip
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.68 score on a scale — p=<0.0001
Phase 2 N=40 Krill Oil for Pain in Elders
Chronic Musculoskeletal Pain
Primary: Participants With 70% or Greater Adherence Based on Self-reported Daily Diary — 18; 17 Participants
N/A N=25 MONOVISC for Shoulder Joint Pain Relief Due to Osteoarthritis
Osteo Arthritis Shoulders
Primary: Numerical Rating Scale (NRS) Pain — -4.12 score on a scale — p=<0.0001
N/A N=25 MONOVISC for Ankle Joint Pain Relief Due to Osteoarthritis
Osteoarthritis Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.00 score on a scale — p=<0.0001
Phase 2 N=51 Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements
Edematous · Synovitis · Foreign Body Reaction
Primary: Pain Visual Analog Scale (VAS) — 57; 46.8; 39.7; 39.1 units on a scale — p=0.0063
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
Phase 2 N=164 Bonipar for Acute and Chronic Musculoskeletal Pain
Chronic Pain · Musculoskeletal Pain
Primary: Change in Pain as Measured by Subjective Pain Intensity Rating (SPIR) — -2.3; -2.6 score on a scale — p=0.46
N/A N=32 Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation.
Inflammation · Knee Pain Chronic
Primary: Points Change of Pain Evaluation Scale — 1.49; 1.15; 1.15; 1.14 score on a scale — p=0.478
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
N/A N=9 Nutramax Joint Health Formulation Biochemical Response Study
Osteoarthritis, Knee
Primary: Serum Biomarkers — 130; 114; 109; 63 pg/ml
N/A N=55 Analgesic Ointment on Temporomandibular Joint and Masticatory Muscle Pain
Temporomandibular Disorders
Primary: The Efficacy in the Treatment of TMJ and Muscle Pain — 21.93; 40.81 units on a scale
N/A N=25,871 Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain
Autoimmune Diseases · Systemic Inflammatory Process · Knee Pain Chronic
Primary: Serum Levels of Biomarkers of Systemic Inflammation: Interleukin-6 (IL-6) — 1.71; 1.68; 1.69; 1.70 pg/ml — p=0.02
N/A N=251 Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
Osteoarthritis of Knee
Primary: Change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). — -6.5; -3.8; -7.4; -6.3 units on a scale
Phase 2 N=60 Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
Knee Osteoarthritis
Primary: Change in Pain Units on a Scale (0-10) 0 Being Least, 10 Being Worst Pain From Baseline — -3.56; -3.29; -1.00 units on a scale
Phase 2 N=58 Maximizing Analgesia to Reduce Pain in Knee Osteoarthritis
Knee Osteoarthritis
Primary: Largest Change From Baseline on Clinical Pain Rating — 24.19; 30.48; 28.55; 26.38 score on a scale — p=.021
Phase 2 N=200 Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
Osteo Arthritis Knee · Arthritis
Primary: Change in Pain Units on a Scale (0-10) 0 Being Least, 10 Being Worst Pain (Value at 8 Weeks Minus Value at Baseline). — -3.7; -3.02; -1.61 units on a scale
N/A N=50 Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery
Postoperative Pain · Delirium · Confusion
Primary: Perioperative Sleep Efficiency — 20; -55 minutes
Phase 2 N=39 Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias
Arthralgia · Breast Cancer
Primary: Absolute Change in Brief Pain Inventory (BPI) Worst Pain From Baseline to Week 15 — -2.4 units on a scale
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
N/A N=23 Jointstrong Intervention for Juvenile Arthritis
Juvenile Arthritis
Primary: Pain — 4.3; 5.7 units on a scale
N/A N=34 Effectiveness of Biofreeze® on Shoulder Pain and In-office Exercise Performance
Shoulder Pain
Primary: Change From Baseline of American Shoulder and Elbow Surgeons (ASES) Questionnaire at 2 Weeks — 72.6; 68.75 units on a scale
N/A N=73 A Behavioral Intervention for Depression and Chronic Pain in Primary Care
Chronic Pain · Depression
Primary: Change in Clinically Significant Depressive Symptoms, as Measured by the Montgomery Asberg Depression Rating Scale (MADRS) — 19.37; 20.87; 14.88; 18.67 score on a scale…
Phase 3 N=220 Efficacy of Shinabro in Hand Osteoarthritis
Hand Osteoarthritis
Primary: AUSCAN Pain Change at 4 Weeks From Baseline — -9.0; -2.2 units on a scale — p=0.014
N/A N=14 Effects of Reparel™ Knee Sleeve on Knee Osteoarthritis
Knee Osteoarthritis
Primary: University of California, Los Angeles (UCLA) Activity Score — 5.4 score on a scale
Phase 4 N=200 Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection
Chondromalacia · Osteoarthritis · Traumatic Arthritis
Primary: 100 mm Visual Analogue Score (VAS) — 32.11; 41.14 score on a scale
Phase 4 N=114 Arthralgia During Anastrozole Therapy for Breast Cancer
Early Breast Cancer
Primary: Number of Participants With New Events of Arthralgia — 37 Participants
Phase 2 N=18 Is Topical CBD Effective in Treating Thumb Joint Arthritis
CBD · Hand Osteoarthritis
Primary: Change in Hand Strength During Intervention and at Follow-up. — 24; 23 KG