Phase 2 N=10 RA-4: 13-cis Retinoic Acid for Treatment of Men With Azoospermia
Male Infertility, Azoospermia
Primary: Total Motile Sperm — 8; 1 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=62 Reproductive Hormonal Alterations in Obesity
Obesity
Primary: Changes in Luteinizing Hormone (LH) Pulse Amplitude (Aim 1) — 4.1; 3.6 IU/L
N/A N=272 Contraceptive Awareness and Reproductive Education
Pregnancy · Sexually Transmitted Infections
Primary: Number of Participants With Continuous Use of Highly Effective Contraceptives Over 9 Months. — 39; 29 Participants — p=>.05
Phase 2 N=40 HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone
Healthy Males
Primary: Serum Testosterone (T) — 0.43; 1.5; 3.7; 8.4 nmol/liter — p=<0.05
N/A N=182 Reproductive Health Survivorship Care Plan
Breast Cancer · Hot Flashes · Sexual Dysfunction
Primary: Number of Participants With a 50% Decrease in Hot Flash Score — 50; 53 Participants
Phase 4 N=112 Follicular Steroid Genesis in Controlled Ovarian Stimulation
Infertility · Controlled Ovarian Hyperstimulation
Primary: SERUM PROGSTERONE CONCENTRATION — 0.74; 0.45 ng/mL — p=<0.05
N/A N=990 Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization
Contraception
Primary: Proportion of Subjects Reporting AEs of Chronic Lower Abdominal and/or Pelvic Pain After Insertion of Essure System or After Laparoscopic Tubal Sterilization — 39; 28…
Phase 2 N=26 A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis
Tuberculosis, Pulmonary · Tuberculosis, Multidrug-Resistant · Tuberculosis, MDR
Primary: Change Form Baseline Total Sperm Count — 20 10^6 sperm cells/ejaculate
Phase 3 N=254 Clinical Safety Study of the Progesterone Vaginal Ring in Women Undergoing Assisted Reproductive Technology Procedures
Progesterone Supplementation in Women Undergoing ART
Primary: Cumulative Rate of Spontaneous Abortions Occurring on or Before 12 Weeks Post-oocyte Retrieval — 7.4 percentage of participants
Phase 2 N=40 ITT4 Intratesticular Hormonal Milieu in Man (ITT4)
Healthy Males
Primary: Intratesticular Testosterone (IT-T) Level — 14; 3.7; 1.7; 18.4 ng/mL — p=<0.05
N/A N=28 Investigating the Physiological Effects of Weight Loss on Male Fertility
Male Infertility · Obesity · Weight Loss
Primary: Sperm Concentration — 53.6; 58.5; 20.1; 15 million sperms/mL
Phase 2 N=20 RA-2 13-cis Retinoic Acid (Isotretinoin)
Male Infertility · Klinefelter's Syndrome · Y-chromosome Microdeletions
Primary: Millions of Sperm Per Ejaculate — 2.5; 3.8 Millions of sperm per ejaculate
N/A N=241 Prednisolone Improves IVF Outcomes in Men With Anti-sperm Antibodies
Reproductive Sterility
Primary: Number of Control and Treated Participants With Successful Live Births Following Conventional IVF or ICSI Cycles — 18; 13; 8; 9 participants
Phase 2 N=59 GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
Amenorrhea · Premature Ovarian Failure · Ovarian Function Insufficiency
Primary: Number of Participants With Secondary Amenorrhea Following 3-month Depot Leuprolide — 37 participants
Phase 3 N=202 PERgoveriS In Stratified Treatment for Assisted Reproductive Technique
Assisted Reproductive Techniques · Reproductive Technology, Assisted
Primary: Total Number of Oocytes Retrieved — 10.9; 9.7 oocytes
Phase 4 N=23 Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study
Infertility
Primary: Oocytes — 19; 47 oocytes
Phase 1 N=99 Study of the Safety, and Sperm and Gonadotropin Suppression of a Contraceptive Gel in Normal Men
Contraception
Primary: The Number of Men Who Have Suppression of Sperm Production ≤1Million/mL Million/mL When Using a Daily Regimen of Nestorone® Gel (0, 8 or 12 mg) and Testosterone Gel…
N/A N=40 Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
Contraception
Primary: Mean Difference Between Pre and Postoperative Hemoglobin (g/dl) — 1.4; 1.8 g/dL — p=0.08
Phase 3 N=27 Immunogenicity of Repeated Follicle Stimulating Hormone (FSH) Stimulation Cycles
Oocyte Donation
Primary: Number of Patients Producing Anti-FSH Antibodies. — 0 participants
N/A N=31 ESS505 Pre-hysterectomy Protocol
Contraception
Primary: Number of Occluded Fallopian Tubes 60 Minutes After Placement of the Insert as Measured by an HSG Evaluation — 36; NA; NA; NA Occluded fallopian tubes
N/A N=11 HSG and Tubal Patency Study
Tubal Patency
Primary: Number of Participants With Bilateral Tubal Patency as Assessed by HSG-follicular — 9; 1 Participants — p=0.4795
Phase 2 N=92 The Effects of Reproductive Hormones on Mood and Behavior
Healthy Volunteers
Primary: Mean Beck Depression Inventory Score — 1.4; 1; 1.1 Units on a scale
N/A N=38 Reproductive Health Survivorship Care Plan Pilot
Breast Cancer · Hot Flashes · Vaginal Dryness
Primary: Hot Flash Frequency — 2.2; 1.4 daily hot flashes
N/A N=24 Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion
Sterilization, Female · Fallopian Tube Occlusion
Primary: Intrauterine Fluid Volume Lost — 2.2; 7.8 ml