N/A N=25 Respiratory Muscles and Inspiratory Muscle Training
Respiratory Muscles · Breathing Exercises
Primary: Diaphragm Electromyography — 60; 55 %max
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=146 Expiratory Muscle Training in Stroke
Stroke · Mastication Disorder · Temporomandibular Disorders
Primary: Change in Masticatory Performance — 24; 13; 25; 16 percentage of masticated peanuts
N/A N=126 Effects of Respiratory Muscle Training in Mechanically Ventilated Adults
Respiratory Muscle Weakness
Primary: Weaning Time From Mechanical Ventilation — 5; 5 hours — p=0.84
Phase 3 N=42 Expiratory Muscle Training for Persons With Neurodegenerative Disease
Parkinson's Disease · Multiple Sclerosis
Primary: Maximum Expiratory Pressure (MEP) — 78.6; 75.56; 99.00; 99.38 cm H2O — p=0.899
N/A N=9 Respiratory Muscle Training (RMT) in ALS
ALS
Primary: Number of Participants With Safe, Well-tolerated Moderate Intensity Respiratory Muscle Training (RMT) as Measured by Rating of Perceived Exertion (RPE) — 4 Participants
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=546 Inspiratory Strength and Respiratory Complications After SCI Injury
Spinal Cord Injuries · Pneumonia
Primary: Pneumonia — 70 Participants
Phase 4 N=63 Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients
Cancer
Primary: Sniff Nasal Inspiratory Pressure (SNIP) — 90; 87; 89; 109 cmH20
N/A N=20 Respiratory Muscle Strength Training in Presbyphonia
Presbylarynx
Primary: Post-Treatment Mean in Voice Handicap Index Score — 15.00; 15.75; 18.50 score on a scale — p=0.041
N/A N=16 Inspiratory Muscle Training and Asthma
Asthma
Primary: Maximal Inspiratory Mouth Pressure (MIP) — 9.36; 9.37; 10.55; 9.21 kPa
N/A N=14 Dynamic Respiratory Muscle Function in Late-Onset Pompe Disease
Pompe Disease
Primary: Inspiratory Load Compensation - Inspiratory Volume — 288.41; 554.34; 743.71; 927.57 mL
N/A N=27 Inspiratory Muscle Rehabilitation in Children With Obesity
Pediatric Obesity
Primary: Number of Participants Who Complete Study Visit 3 — 12; 13 Participants
N/A N=25 Respiratory Strength Training in Cardiac Surgical Patients
Cardiovascular Diseases · Thoracic Diseases · Surgery
Primary: Adherence to Respiratory Strength Training — 35750 Repetitions
N/A N=6 Diaphragm Pacing in Individuals With Spinal Cord Injuries
Cervical Spinal Cord Injury
Primary: Change in Electromyogram (EMG) — -.0031 mV
N/A N=7 A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU
Critically Ill · Respiratory Failure
Primary: Safety and Feasibility of Inspiratory Muscle Training — 3; 3 Participants
N/A N=38 Effects of Inspiratory Muscle Training in Patients With Bronchiectasis
Bronchiectasis
Primary: Maximum Inspiratory Pressure (MIP) and Maximum Expiratory Pressure (MEP) at 8 Weeks — 60; 71; 84; 69 cmH2O — p=0.005
N/A N=24 Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI
OSA · SCI/D · Upper Airway Exercise
Primary: Feasibility-Number of Participants Who Complete the Three-month Protocol — 8; 10 Participants
Phase 3 N=75 Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex
Diaphragmatic Dysfunction · Muscle Weakness · Muscle Fatigue
Primary: Electric Activity of the Diaphragm (Microvolts) — 3.7; 4.5; 3.2; 2.9 microvolt
N/A N=54 Electrical Activation of The Diaphragm for Ventilatory Assist
Spinal Cord Injury · Quadriplegia
Primary: Enrolled Subjects Achieve Clinically Acceptable Tidal Volume Sustained Over a Continuous 4 Hour Period. — 52; 1 Participants — p=<0.001
Phase 4 N=70 Stacking Exercises Aid the Decline in FVC and Sick Time
Duchenne Muscular Dystrophy
Primary: Change in FVC (%-Predicted) From Baseline to 2 Years. — -9.2; -6.4 Mean difference in FVC %-predicted — p=0.68
N/A N=29 Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease
Amyotrophic Lateral Sclerosis (ALS) · Neuromuscular Diseases
Primary: Percent Change in Maximal Inspiratory Pressure (MIP) — 0.3; -3.1; -4.8; -5.0 percentage change in MIP from baseline
N/A N=133 Mechanisms of Upper Airway Obstruction
Obstructive Sleep Apnea
Primary: Pharyngeal Critical Pressure (Pcrit) — 1.26; -1.42; -1.06 cm H2O — p=.80
N/A N=41 Vocal Warm-up and Respiratory Muscle Training
Voice Disorders
Primary: Voice Handicap Index (VHI-10) — 20.44; 13.82 units on a scale — p=0.001
N/A N=6 Sub-study to Spinal Cord Stimulation to Restore Cough
Spinal Cord Injuries · Spinal Cord Diseases · Paralysis
Primary: The Effects of Electrical Spinal Cord Stimulation (SCS) on Airway Pressure Generation While Using Temporarily Placed Parallel Wire Leads and Implanted Disc Electrodes…
N/A N=15 Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury
Spinal Cord Injury
Primary: Change in Peak Aerobic Capacity During FES-row Testing — 1.83; 1.82 L/min
N/A N=14 Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients
Covid19 · Respiratory Function Loss · Coronavirus Infection
Primary: Change in Peak Expiratory Flow (Absolute Value) — 175; 160 ml/min — p=0.374
N/A N=21 Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease
Neuromuscular Diseases
Primary: Change From Baseline Vital Capacity at One Year. — 33.33; -7.41 percentage of Change of vital capacity — p=<0.001
N/A N=75 Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women
Healthy Individuals
Primary: Thoracic Mobility — 2.87; 2.78; 3.47; 2.86 cm — p=0.05
Phase 2 N=25 Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults
Cough
Primary: Lung Volume Initiation — 23.3 % Vital Capacity, relative to EEL
N/A N=20 Comparing Nose & Mouth Breathing During Exercise
Healthy
Primary: Blood Pressure During Exercise Between Study Arms — 142; 146 mmHg