Clinical Trial Search

Primary: Change in Scar Pliability Between the Treated and Control Incision Sites as Measured by Skin Elasticity at 6 Months Compared to Baseline

Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05

Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale

Primary: Physician Global Assessment Using Physician Overall Opinion Question of Patient and Observer Scar Assessment Scale (POSAS) — 4.00; 4.68; 4.61; 4.86 units on scale…

Primary: Scar Pigmentation, Baseline vs 15-months — 50.93; 49.59 units on a scale

Primary: Cosmetic Outcome — 7.4; 6.6; 6.3; 6.00 score on a scale

Primary: Modified Manchester Scar Scale (MMSS) Score — 8; 11.5 score on a scale

Primary: Improvement of Surgical Scars at 12 Months Compared to Baseline (Pre-treatment) as Evaluated by 3 Independent Blinded Reviewers Using the General Aesthetic Improvement…

Primary: Assessment of Visual Analog Scale (VAS) Change (Values From 0 (Worst) to 10 (Best)) — 0; 50 Percentage reporting improvement

Primary: Patient Observer Scar Assessment Scale (POSAS) — 17.69; 11.2; 15.2; 11.4 units on a scale — p=0.019

Primary: Safey Data Score Based on Ordinal Ratings of Erythema, Edema, Bleeding, Eschar After Resurfacing — 1.33; 3.00; 0; 0 units on a scale

Primary: Visual Analogue Scale (VAS) — 2.90; 3.29 score on a scale

Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale

Primary: Contracture of Scar Surface Area (Percentage of Original Area) — 97; 97 percentage

Primary: Patient and Observer Scar Assessment Scale (POSAS) - PI Assessment — 4.4; 4.5 score on a scale

Primary: The Measured Difference in POSAS and VAS Scores Between 7-day and 10-day Groups — 12.9; 16.1; 19.5; 20.3 score on a scale

Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale

Primary: Post-operative Scarring - Erythema — 1.67; 1.70; 1.50; 1.65 score on a scale — p=0.48

Primary: Change in Keloid Surface Area — 0.455; -0.039 cm2

Primary: Physician Observer Scar Assessment Score at Week 24 — 0.0; -0.5; 0.8; -0.3 units on a scale — p=1.000

Primary: Photography- Independent Scar Assessment Panel

Primary: Change in Vectra Measured Length V1 (Month 0)-V2 (Month 3) for Original Group; Visit 3 (Month 6) to Visit 4 (Month 9) for Crossover Group — 0.10; 0.03 mm

Primary: Mean Change From Baseline in Erythema — -1.687; 5.730 units on a scale

Primary: Percentage of Subjects With Confirmed Keloid Formation at Treated vs. Untreated Lesions at 24 Weeks — 92.9; 85.7 percentage of participants

Primary: Scar Pain — 1.265; 1.181; 1.048; 1.084 units on a scale — p=0.0492

Primary: Subjective Cosmetic Result — 13; 26.5 units on a scale

Primary: Expert Panel Scar Assessment Score at Week 12 — 36.6; 51.4 millimeter — p=<0.001

Primary: POSAS (The Patient and Observer Scar Assessment Scale) Measure — 2.5; 2.5; 2.5 Score

Primary: Part B: Expert Panel Scar Assessment Score — -3.16; 0.18; 1.45; 2.91 millimeters

Primary: Change From Baseline in Vancouver Scar Scale Score(VSS) at 3 Months — -3.80; -2.61 units on a scale