N/A N=17 Palliative Strategies in Spinal Cord Injury (SCI)
Spinal Cord Injury
Primary: Muscle Mass Via Dual-Energy X-ray Absortiometry (DEXA)Scan Data — 6104.45; 6355.3 grams — p=.318
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=3 Spinal Cord Stimulation in Spinal Muscular Atrophy
Spinal Muscular Atrophy Type 3 · Spinal Muscular Atrophy Type 4
Primary: Muscle Weakness — 2; 3 Participants
Phase 1 N=23 Spinal Excitation to Enhance Mobility
Aging
Primary: Walking Speed Change From Baseline — .054; .078; .085; .039 meters/second
N/A N=24 Spinal Cord Injury - Exercise
Spinal Cord Injuries
Primary: Effect of Exercise on Inflammation (C-reactive Protein) — 0.00; 0.05 mg/dL
N/A N=42 Improving Motor Function After Spinal Cord Injury
Spinal Cord Injury
Primary: Physiology Measurements Before and After rTMS/Sham rTMS Protocol- Changes in Amplitude of Motor Evoked Potential (MEP) From TMS — 0.31; 0.43; 0.45; 0.65 millivolts (mV)
Phase 2 N=4 Neuromodulation Techniques After SCI
Spinal Cord Injury
Primary: 10-meter Walking Speed (m/Sec) — 0.165; 0.215; 0.13; 0.13 speed (m/sec)
Phase 3 N=212 Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
Spinal Cord Injury · Muscle Spasticity
Primary: Double-blind Change From Baseline in Ashworth Score Evaluating Spasticity — -0.19; -0.15 units on a scale
N/A N=18 Spinal Cord Stimulation to Augment Activity Based Therapy
Transcutaneous Spinal Stimulation · Walking · Spasticity
Primary: Change in Walking Function - 10m Walk Walking Speed (m/s) — 0.06; 0.16 speed difference in meters per second
N/A N=36 Spinal Cord Injury Program in Exercise
Spinal Cord Injuries
Primary: Physical Activity Level at Week 8 — 383; 297 Minutes per week
N/A N=17 Spinal Cord Stimulation to Restore Cough
Spinal Cord Injuries · Spinal Cord Diseases · Paralysis
Primary: Effectiveness of Expiratory Muscle Activation to Generate Large Airway Pressures Characteristic of Normal Cough. — 25; 121 cmH2O — p=<0.05
Phase 4 N=27 tSCI Contrast Enhanced Ultrasound Study
Acute Spinal Cord Injury
Primary: Feasibility of Intraoperative Contrast-enhanced Ultrasound in Acute Traumatic Spinal Cord Injury - Number of Participants With Successful Intraoperative…
N/A N=13 Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
Incomplete Spinal Cord Injury
Primary: Percent Change in Hmax — 27.85; 8.43; -4.91; 16.20 percent change in Hmax
Phase 3 N=204 Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
Spinal Cord Injury · Muscle Spasticity
Primary: Double-blind Change From Baseline in Ashworth Score Evaluating Spasticity — -0.28; -0.16 units on a scale
N/A N=21 Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Spinal Cord Injuries · Paraplegia · Paraparesis
Primary: Change in Motor Evoked Potential (MEP) Amplitude in the Tibialis Anterior Muscle at the End of Training. — -1.75; -2.01 Amplitude percentage of Mmax
N/A N=71 Musculoskeletal Plasticity After Spinal Cord Injury
Spinal Cord Injuries
Primary: Acute Gene Regulation: MSTN — 5.49; 4.76 arbitrary units — p=<0.001
N/A N=6 The Effect of FES on Children With Spinal Cord Injury
Spinal Cord Injury
Primary: Change in Pediatric Quality of Life Inventory Version 4.0 (PedsQL 4.0)Score. — 7.08 units on a scale
N/A N=92 Randomized Trial of Early Hemodynamic Management of Patients Following Acute Spinal Cord Injury
Spinal Cord Injury
Primary: Change From Baseline in American Spinal Injury (ASIA) Upper Extremities Motor Score — 15.58; 12.63 Scores on a scale — p=0.55
N/A N=15 Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury
Spinal Cord Injury Cervical · Upper Extremity Dysfunction
Primary: Graded and Redefined Assessment of Strength, Sensibility and Prehension Test (GRASSP Test) — 4.5; 19.4 score change before and after — p=<0.000
N/A N=40 Recovery of Bladder and Sexual Function After Spinal Cord Injury
Spinal Cord Injuries
Primary: Bladder Storage — 278.5; 447.75; 580.5; 313.0 mLH2O
Phase 1 N=12 Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia
Spinal Cord Injury
Primary: Safety-Number of Adverse Events — 69 Adverse events
N/A N=9 Spinal Cord Stimulation to Treat Hypertension
Hypertension
Primary: Change in Exercise Pressor Reflex From Baseline — 8.67; 16.29 mmHG
N/A N=33 The Effects of Spasticity on Glucose Metabolism in Individuals With Spinal Cord Injury
Spinal Cord Injuries
Primary: Correlation Between Knee Flexor Muscle Modified Ashworth Scale and Insulin Resistance — -0.692; 0.23 correlation coefficient — p=0.006
N/A N=10 Transcutaneous Stimulation in Spinal Cord Injury
Spinal Cord Injury
Primary: Seated Systolic Blood Pressure — 86; 100.4; 102.7; 101.3 mmHg
N/A N=15 Changes in Cerebral Blood Flow in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain
Pain · Low Back Pain · Leg Pain
Primary: Cerebral Blood Flow and VAS With Optimal Paresthesia Coverage Compared With SCS Off
N/A N=231 Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc Disease
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
N/A N=26 Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
Spinal Cord Injuries · Metabolic Syndrome · Dietary Modification
Primary: Percent Body Fat Assessed by DXA at Baseline and 21 Weeks — 26.6; 25.9; 22.0; 25.6 % of body fat
N/A N=21 Stereotactic Body Radiation Therapy (SBRT) for Tumors Near the Spinal Cord
Spinal Tumors
Primary: Toxicity — 14; 0; 0; 0 participants
Phase 2 N=61 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
Acute Spinal Cord Injury
Primary: Total Spinal Cord Independence Measure, Version III (SCIM III) Score Following Treatment With SUN13837 Injection or Placebo in Adult With Acute Spinal Cord Injury…
Phase 3 N=65 An Implantable Spinal Cord Stimulation Pain Management System
Chronic Pain · Pain, Intractable · Pain
Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement
Phase 3 N=6 Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.
Spinal Cord Injury
Primary: Change in Trabecular Plate Width (Tb.PW) for Femur and Tibia at 4.5 Months — 1785.42; 1819.41; 1805.52; 1834.67 μm