N/A N=1,869 Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
Surgical Wound Infection
Primary: Wound Infection After Open Heart Surgery — 4; 17 Participants — p=0.55
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=1,502 Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection
Cardiac Surgery · Sternal Wound Infection
Primary: Number of Participants With Surgical Wound Infections From Surgery Through Post-operative Day 90 — 63; 65 Participants
N/A N=80 A Study of Sternal Closure After Open Heart Surgery: Rigid Versus Wire Closure
Pain
Primary: Intubation Time — 7; 9 hours
N/A N=91 Topical Antibiotic Treatment for Spine Surgical Site Infection
Surgical Wound Infection
Primary: Surgeon Attitudes About Using Intra-wound Antibiotics for Spine Surgery — 9; 36; 46 Participants
N/A N=236 An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery
Coronary Artery Disease · Angina Pectoris · Cardiac Valve Disease
Primary: Sternal Healing Score at 3 Month Post op, as Defined by a 6-point Scale to Evaluate Bone Healing — 1.8; 2.6 units on a scale — p=<0.0001
N/A N=164 Negative Pressure Wound Therapy to Reduce Surgical Site Infection
Patients Undergoing Hepatopancreatobiliary Surgery
Primary: Participants With a Surgical Site Infection — 14; 20 Participants — p=0.27
N/A N=140 Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain
Sternal Wound Infection · Sternal Non-union · Pain
Primary: CT Scan Evaluation of Sternal Bone Healing — 0.9; 1.7; 2.2; 3.2 units on a scale — p=0.003
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
N/A N=702 Prospective, Randomized, Parallel-arm Clinical Trial of CleanCision or Alexis O in Elective Colorectal Surgery
Colorectal Surgery
Primary: Surgical Site Infection (SSI) Rate — 16; 14; 6; 1 Participants
N/A N=225 Incidence and Risk Factors for Surgical Site Infection After Intramedullary Nailing of Femoral and Tibial Fractures
Fracture Fixation, Intramedullary · Surgical Wound Infection
Primary: Incidence of Surgical Site Infection (SSI) Relating to Intramedullary Nailing for Fixation of Diaphyseal Femoral and Tibial Fractures — 26; 195 Participants
Phase 4 N=51 Rapid Sternal Closure System (TALON)
Sternal Wound Infection · Mediastinitis
Primary: Percentage Change of Preoperative Incentive Spirometry (IS) Volume Achieved — 58; 67 percentage change — p=0.41
Phase 2 N=104 Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction
Nonmalignant Breast Conditions · Breast Cancer
Primary: Number of Subjects With Drain Bulb Fluid Bacterial Colonization at Approximately 1 Week — 10; 21 participants — p=0.02
Phase 4 N=10 Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions
High Risk Abdominal Wounds
Primary: Number of Participants With Surgical Site Infections Within 1 Month (4 Weeks ) From Index Operation — 1 Participants
N/A N=120 Prophylactic Incisional Care in Obese Women at Cesarean
Wound Infections
Primary: Number of Participants With Composite Surgical Site Infection (SSI) or Other Wound Complication. — 5; 3 Participants — p=0.72
N/A N=109 Wound Infection Alexis Wound Retractor
Appendicitis
Primary: Post-operative Wound Infection, After Open Appendectomy — 1; 7 Participants
N/A N=180 Study Evaluating Severe Surgical Site Infections (SSIs) Following Contaminated Or Dirty-infected Abdominal Surgery
Surgical Wound Infection · Postoperative Wound Infection
Primary: Percentage of Participants With Pre-surgical Morbidities — 47.8; 48.9; 26.7; 23.3 percentage of participants — p=0.881
Phase 3 N=60 Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride
Coronary Artery Disease · Coronary Artery Stenoses · Valve Regurgitation, Mitral
Primary: Post-operative Pain Intensity — 4.7482; 5.03; 5.75; 6.64 score on a scale
N/A N=124 Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Surgical Site Infection · Pancreatic Neoplasms · Pancreatic Cancer
Primary: Rate of Surgical Site Infection — 6; 19 Participants — p=0.003
N/A N=1,064 Effect of Prophylactic Negative Pressure Versus Silver Impregnated Silicone Bandage on C-Section Infection Rates
D001458 · D011247
Primary: Infection Rate — 17; 18; 5; 5 Participants
N/A N=13 Effects of Sternal Wall Pressure in Children
Respiration, Artificial
Primary: Sternal Force Associated With Change in Intrathoracic Pressure. — 2.8 kg
Phase 3 N=250 Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)
Ventral Hernia Repair
Primary: Surgical Site Infection — 11; 10 Participants
Phase 4 N=647 Multicenter Infection Surveillance Study Following Open Heart Surgery
Surgery · Pneumonia · Surgical Site Infection
Primary: Hospital Acquired Pneumonia — 8; 18 participants
N/A N=105 Prevena™ vs Dermabond in Groin Wound Infections in Vascular Surgery
Wound Infection
Primary: Comparison of Healing of Groin Wounds Between Patients Treated With Prevena vs Dermabond — 41; 54 Participants
N/A N=41 Wound Vac Bandage Comparison After Spinal Fusion
Neuromuscular Scoliosis
Primary: Number of Participants With Wound Dehiscence or Infection — 0; 0 Participants
Phase 4 N=1,697 Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin
Surgical Site Infection
Primary: Surgical Site Infections Occurring Within 12 Months of Surgical Procedure — 0; 5 participants
N/A N=88 Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation
Breast Cancer
Primary: Number of Participants With Surgical Site Infection — 7; 4 participants
N/A N=300 Supplemental Oxygen Reduces Surgical Infection
Wound Infection
Primary: Incisional Surgical Wound Infection — 22; 35 participants — p=0.04
Phase 3 N=157 2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Surgical Site Infections · Post Operative Complication
Primary: Participants With Surgical Site Infection Development at 30 Days Post-operative — 5; 5 Participants — p=0.456
Phase 4 N=110 S. Aureus Screening and Decolonization
Wound Infection Due to Staphylococcus Aureus · MRSA Infection of Postoperative Wound
Primary: Eradication of Staphylococcus Aureus (SA) Carriage at All 4 Body Sites Tested. — 13; 41 Participants
N/A N=40 Prophylactic Application of an Incisional Wound Vac to Prevent Wound Complications in Obese Spine Surgery Patients
Spine Surgery · Wounds Vac
Primary: Count of Patients With Post Operative Infection — 4; 2; 5; 3 Participants