N/A N=91 Cortisol Suppression and Startle Responses in Posttraumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder
Primary: Mean Baseline Startle Magnitude During Fear Conditioning — 48.401; 56.595; 115.778; 57.684 microvolts
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=139 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
Stress Disorder - Post-traumatic (Acute)
Primary: Severity of PTSD Symptoms — 43.4; 43.9 CAPS total Score at treatment end — p=0.927
N/A N=60 Implementing a Skills Training Evidence-Based Treatment for Posttraumatic Stress Disorder in Primary Care
Posttraumatic Stress Disorder
Primary: Posttraumatic Stress Disorder Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5) — 61.48; 58.28; 39.12; 36.30 score on a scale
N/A N=120 Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Post-traumatic Stress Disorder · Alcohol Abuse · Alcohol Dependence
Primary: Number of Patients With High Levels of Adolescent PTSD Symptoms — 9; 12; 11; 12 Participants — p=0.71
N/A N=112 The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk
PTSD
Primary: Change From Baseline to Post-Intervention in 24-hour Heart Rate Variability (HRV) Estimated From the Standard Deviation of the Interbeat Interval of Normal Sinus Beats…
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
Phase 3 N=80 Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Stress Disorders, Post-Traumatic
Primary: Change Scores for Criteria D Items on the CAPS Structured Clinical Interview — -1.20; -6.27 units on a scale — p=.27
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
N/A N=169 Brief Treatment for Posttraumatic Stress Disorder
PTSD
Primary: Clinician Administered PTSD Scale, 5 (CAPS-5) — 31.55; 25.12; 29.59; 25.41 score on a scale
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=124 Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
Post-traumatic Stress Disorder
Primary: Weekly Number of Nightmares — 3.95; 3.88; 3.28; 3.47 weekly nightmares
Phase 4 N=41 Vortioxetine for Posttraumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: Change Clinician Administered PTSD Scale Score — 16; 17 score on a scale
N/A N=25 DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Stress Disorders, Post-Traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 63.08; 61.71; 42.83; 51.65 units on a scale
N/A N=50 Women's Post Traumatic Stress Disorder (PTSD) Research Study
Posttraumatic Stress Disorder
Primary: Prepulse Inhibition — -.19; -.31 proportion of change in OEMGR response
N/A N=30 EEG Personalized Transcranial Magnetic Stimulation (eTMS) for Post-Traumatic Stress Disorder
Stress Disorders, Post-Traumatic
Primary: Number, Severity, Relatedness, Type, Subsequent Treatment/Intervention Required, and Resolution Status of Adverse Events (AEs) During the Study. — 26; 3; 2; 17 Number of…
N/A N=81 Cognitive Training for PTSD
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale - Reexperiencing — 2.6; 2.96 score on a scale
N/A N=69 Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD
PTSD
Primary: Change in Clinician-Administered PTSD Scale for DSM-5 — 38.39; 35.67; 27.15; 29.31 score on a scale — p=0.4154
Phase 4 N=37 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (CAPS) — 72.6; 65.4; 40.7; 49.0 units on a scale — p=.01
N/A N=85 Breathing Meditation Intervention for Post Traumatic Stress Disorder
Stress Disorders, Post-Traumatic
Primary: Change in PTSD Checklist (PCL) — -5.6; -6.8; -4.8; -6.8 score on a scale
N/A N=131 Trauma-Sensitive Yoga for Female Veterans With PTSD Who Experienced Military Sexual Trauma
Stress Disorders, Post-traumatic
Primary: Clinician Assessed PTSD Checklist-5 (CAPS-5): Change in Mean Total Severity Scores From Baseline to 3-months Post-intervention — -11.41; -14.48 score on a scale
Phase 4 N=41 Suvorexant and Trauma Related Insomnia
Insomnia · Posttraumatic Stress Disorder
Primary: Change in Insomnia Severity Index Score From Baseline. — 6.8; 8.6 units on a scale — p=<.05
N/A N=83 Family Involvement in Treatment for PTSD
Posttraumatic Stress Disorder
Primary: Qualitative Interviews - Perspectives on Family Involvement in PTSD Treatment — 33; 20; 27; 16 participants — p=<0.05
N/A N=93 Recovery After Stress Toolkit (RESET) Study
Post-Traumatic Stress Disorder in Children · Post-Traumatic Stress Disorder in Adolescence
Primary: Child PTSD Symptom Scale (CPSS) — 10.4; 14 Score on a scale
N/A N=121 Trauma Survivors Outcomes and Support Study IV
Posttraumatic Stress Disorder · Depression · Suicide
Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05
Phase 3 N=200 Comparison of Two Treatments for Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: PTSD Symptoms — 10.02; 10.87; 15.12; 10.78 units on a scale
Phase 4 N=700 Sequenced Treatment Effectiveness for Posttraumatic Stress
PTSD
Primary: PTSD Symptoms — 39.3; 38.6; 40.5 units on a scale
Phase 3 N=36 Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
Combat Disorders · Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (Pre & Posttreatment) — 30.0; 53.6 units on a scale
Phase 4 N=40 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)
Post-Traumatic Stress Disorder
Primary: Clinician-Administered PTSD Scale (CAPS) — 79.1; 81.9; 90.0; 91.0 units on a scale — p=0.286
Phase 4 N=65 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD)
Post-traumatic Stress Disorder
Primary: Percent Change in Brain Response Measured by Functional Magnetic Resonance Imaging (fMRI) — -.92; .07 percent change in BOLD signal — p=.001
N/A N=31 Information Processing Modification in PTSD (Oct. 18)
Stress Disorders, Post-traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 57.14; 61.33; 52.21; 53.78 units on a scale