Phase 2 N=5 Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome
Sturge-Weber Syndrome
Primary: Number of Seizures Per Month — 33.5; 30.0; 3.0; 0.5 Seizures per month
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=10 Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome
Sturge-Weber Syndrome
Primary: Change in Cognitive Function as Assessed by the National Institute of Health (NIH) Toolbox Cognitive Battery — 44.2; 42.3; 34.1; 35.2 T score
Phase 2 N=10 Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome
Sturge-Weber Syndrome
Primary: List Sorting Working Memory Test — 37.14; 39.14 T-score
N/A N=357 Hemangioma Associated With High Rates of Morbidity
Hemangioma
Primary: MRI/MRA of Head/Neck/Chest. — 357 participants
N/A N=27 Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks
Port Wine Stain
Primary: Change From Baseline in a* and E at 8 Weeks — 1.27; 0.43; 4.08; 2.59 units on a scale
N/A N=17 Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains
Port Wine Stains
Primary: Blanching of Port Wine Stain Birthmark — 16 participants
N/A N=22 Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment
Port-Wine Stain
Primary: Percent Change in Blanching of Port Wine Stain — 6; 5 percentage
Phase 2 N=84 Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex
Tuberous Sclerosis Complex
Primary: Cognitive Assessment Scores and Developmental Impact — 83.9; 80.9; 97.3; 85.0 score on a scale — p=0.8681
Phase 3 N=20 Treatment of Sunflower Syndrome With ZX008 (Fenfluramine Hydrochloride) in Children and Young Adults (Ages 4-25).
Photosensitive Epilepsy
Primary: % Change in Frequency of Handwaving Episodes — -66.2 % change in hand waving episodes — p=<0.001
N/A N=12 MRI for Non-invasive Evaluation of Brain Stress
Craniosynostosis
Primary: Blood Flow and Perfusion — 26.8 ml/min/100g — p=0.004