N/A N=10 Somatosensory Tinnitus Study
Tinnitus
Primary: Tinnitus Functional Index — 57.7; 39.6 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=12 rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study
Tinnitus
Primary: Average Change (Baseline-End of Treatment) Tinnitus Handicap Inventory (THI) — 10.7 units on a scale
N/A N=20 Resting-State Neural Connectivity in Patients With Subjective Tinnitus Without Bother
Tinnitus
Primary: Number of Participants With Changes in Blood Oxygen Level as Measured by Functional Connectivity MRI — 18 participants — p=<0.01
N/A N=108 Cognitive Speed as an Objective Measure of Tinnitus
Tinnitus
Primary: Brain Speed Test — -0.09 z-score
N/A N=21 Auditory-somatosensory Stimulation to Alleviate Tinnitus
Tinnitus
Primary: Change in TFI (Tinnitus Functional Index) After Treatment or Sham Compared to Baseline — -10.08; -5.40; 0.95; -4.34 units on a scale — p=<0.05
N/A N=290 Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial
Tinnitus
Primary: Tinnitus Questionnaire (TQ, Goebel and Hiller 1998) Total Score Change From Baseline to End of Treatment — 13.6; 3.7 absolute TF-score change
Phase 2 N=43 OTO-313 in Subjects With Subjective Tinnitus
Tinnitus, Subjective
Primary: Audiometry - Pure Tone Average Done Over 1000, 2000 and 4000 Hertz (HZ) — -0.3; 0.71; -0.8; 0.3 decibels
N/A N=39 Effect of rTMS on Resting State Brain Activity in Tinnitus
Tinnitus
Primary: Change From Baseline on the Analogue Rating of Tinnitus Awareness. — -4.08; -4.70; -9.82; -9.89 units on a scale — p=.04
N/A N=100 Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts
Tinnitus
Primary: Change in Objective Tinnitus Loudness — -6.1; -9.5; -10.2; -11.0 decibels sensation level (dB SL)
N/A N=22 Cochlear Promontory Stimulation for Treatment of Tinnitus
Tinnitus
Primary: Change in Short Term Relief of Tinnitus as Measured by the Tinnitus Handicap Inventory — -31 score on a scale
N/A N=65 Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus
Tinnitus · Hearing Aids · Normal Hearing
Primary: Tinnitus Functional Index Change — 53.31; 44.10; 64.93 units on a scale
N/A N=5 Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus
Tinnitus
Primary: Change in PET Asymmetry Index — 1.2 ratio
Phase 2 N=153 OTO-313 in Subjects With Unilateral Subjective Tinnitus
Subjective Tinnitus
Primary: Percentage of Tinnitus Functional Index (TFI) Responders at Weeks 4 and at Week 8 — 20; 27 Participants — p==0.385
N/A N=64 Neurobiological Similarities of Tinnitus and PTSD
Posttraumatic Stress Disorder · Tinnitus
Primary: Resting-State Functional MRI — 0.55; 0.35; 0.29; 0.59 Z-Score — p=0.01
N/A N=32 Action of Intra-auricular Topical Lidocaine on Tinnitus
Tinnitus, Subjective
Primary: Change in Visual Analogue Scale (VAS) Score — 6.3; 6.3; 5.5; 5.2 score on a scale
Phase 2 N=10 An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus
Tinnitus
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAE) — 1 Participants
N/A N=126 Internet-based Cognitive Behavioral Therapy for Tinnitus Sufferers
Tinnitus
Primary: Tinnitus Functional Index (TFI); Measure of Tinnitus Distress — 48.7; 50.52; 32.13; 28.95 score on a scale
Phase 2 N=25 Cognitive Behavioral Therapy (CBT) for Tinnitus
Tinnitus
Primary: Tinnitus Handicap Inventory (THI) — 37.9; 45.1; 42.67; 26.0 units on a scale of 0-100 — p=<0.05
N/A N=158 CBT-based Internet Intervention for Adults With Tinnitus in the United States
Tinnitus
Primary: Tinnitus Functional Index (TFI) - Measure of Tinnitus Distress — 54.04; 53.93; 29.44; 47.35 score on a scale
N/A N=38 Evaluation of the Clinical Benefit of the Hearing Aids Tinnitus Feature.
Hearing Loss, Sensorineural · Tinnitus
Primary: Tinnitus Functional Index Evaluation (TFI) — 35.6; 32; 44.8; 36.2 units on a scale
Phase 2 N=70 Transcranial Magnetic Stimulation for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) Score — -13.8; -2.9 units on TFI scale; change from baseline
Phase 2 N=42 Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus
Tinnitus
Primary: GABA and Glutamate (Glx) Levels in the Auditory Cortex Derived From 3T Magnetic Resonance Spectroscopy — 2.11; 2.12; 2.09; 2.03 Ratio — p=0.05
N/A N=61 Clinical Trial of Sound-Based Versus Behavioral Therapy for Tinnitus
Tinnitus
Primary: Tinnitus Questionnaire (TQ) — 34.3; 35.1 score on a scale
Phase 4 N=40 Nitrous Oxide Treatment for Tinnitus
Tinnitus
Primary: Change in Tinnitus Functional Index (TFI) Score — -1.8; -2.5 score on a scale
Phase 3 N=38 A Trial of Magnesium Dependent Tinnitus
Tinnitus
Primary: Tinnitus Distress Rating — 5.71; 5.82; 5.36; 5.46 units on a scale
N/A N=5 rTMS Bimodal Treatment For Tinnitus: A Pilot Study
Tinnitus
Primary: Adverse Events — 0 participants
N/A N=32 Internet-based Cognitive Behavioural Therapy for Spanish Tinnitus Sufferers
Tinnitus
Primary: Tinnitus Functional Index (TFI); Measure of Tinnitus Distress — 61.06; 41.78; 40.38 score on a scale
Phase 2 N=34 Collaborative Tinnitus Research at Washington University
Subjective Tinnitus
Primary: Change in THI (Tinnitus Handicap Inventory) — -5; -6; -10; -6 units on a scale — p=0.944
N/A N=97 Mahana Tinnitus Pilot
Tinnitus
Primary: Mean Change in TFI Score From Baseline to Week 6 — -20.50 score on a scale
Phase 4 N=78 Treatment of Tinnitus With Migraine Medications
Tinnitus, Subjective · Tinnitus
Primary: Tinnitus Functional Index (TFI) — -12.1; -12.4; -6.0 scores on a scale