Clinical Trial Search

Primary: Change in Number of Times Driving After Using Substances — 22.43; 26.50; 26.00 Driving Events

Primary: Ratio of Glutamate to Creatine in the Anterior Cingulate of the Brain, Measured on Day 4 — 1.256772; 1.294178 Ratio of glutamate to creatine

Primary: Change From Baseline in Parenting Skills: Supporting Positive Behavior — 37.35; 37.43; 38.51; 37.49 score on a scale

Primary: Negative Affect — 2.91; 2.47 units — p=.62

Primary: Mean Change in Loneliness From Baseline to 1-month Post-treatment Follow-up — -1.38; -5.40 score on a scale

Primary: Recruitment — 96 Participants

Primary: Mean Peak Opioid Withdrawal Assessed by the Clinical Opiate Withdrawal Scale (COWS) — 12.6; 1.3 units on a scale

Primary: % Change in Frequency of Handwaving Episodes — -66.2 % change in hand waving episodes — p=<0.001

Primary: Youth Enrolled in Substance Use Treatment — 0; 12; 4; 6 Participants

Primary: Unpleasantness of Breathlessness — 69.0; 71.1 units on a scale

Primary: Percent Days Abstinent Per Month From Drug Use — 46.92; 55.16 percentage of days abstinent — p=.02

Primary: # Patients With Composite Endpoint of Experiencing Either Death, Graft Loss, or eGFR < 45ml/Min — 9; 15; 14 Participants

Primary: Number of Participants That Received Rescue Medication for Withdrawal Symptoms Within 1 Hour — 9; 19 Participants

Primary: Change in Total Score on Wisconsin Smoking Withdrawal Scale2 Long (WSWS2-L) — 2.64; 2.36; 2.29; 2.69 score on a scale

Primary: Total Lorazepam Dosage (in Milligrams) — 16.5; 3.4 milligrams of lorazepam