N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=12 Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Amputation
Primary: Mechanical Crank Power Output — 0.59; 0.99; 0.60; 0.97 W/kg
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=20 Functional Electrical Stimulation Use in Trans-tibial Amputations
Traumatic Amputation of Lower Extremity
Primary: Change in Knee Extension Isometric Strength (Peak Torque) Using the Biodex Measurement System — -0.1; 2.2 Nm/kg — p=0.768
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=10 Biomechanical Assessment of Gait in Lower-Extremity-Amputees
Prosthesis User
Primary: Overall Asymmetry Index — 0.064; 0.352; 0.541; 1.481 unit-less index (0 = perfect symmetry)
N/A N=11 Prosthetic Components and Stability in Amputee Gait
Diabetes Mellitus · Leg Injuries · Traumatic Amputation
Primary: Local Dynamic Stability (Hip During Straight Walking) — .74; .74 dimensionless — p=>0.99
N/A N=6 Biomechanical Evaluation of a Novel, Compliant Low Profile Prosthetic Foot
Amputation
Primary: Total Energy Stored (TES) — 20.1; 13.3 Joules
N/A N=68 Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees
Transtibial Amputee
Primary: Number of Participants With Significant Increases in Socket Comfort Score (SCS) — 5; 6; 4 participants
N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
N/A N=6 Basic Mobility and Balance Performance of Low Active Transfemoral Prosthesis Users With a Powered Prosthetic Knee
Prosthesis User · Amputation
Primary: Timed Up and Go Test (TUG Test) — 13.3; 16.8 seconds
N/A N=11 Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation
Lower Extremity Amputation
Primary: Peak Transverse-plane Prosthetic Socket Torque Normalized to Body Mass — 0.299; 0.340; 0.306; 0.292 Nm/kg — p=0.029
N/A N=71 Immediate Fit Using Innovative Technology Transtibial & Transfemoral Prosthesis
Amputation
Primary: Prosthetic Comfort and Utility Questionnaire (Version 1) — 25.52; 29.33 score on a scale
N/A N=12 Lower Limb Prostheses for Individuals Who Carry Infants, Toddlers, and Other Loads
Amputation · Prosthesis User
Primary: Vertical Ground Reaction Force Impulse (Normalized) — 5.24; 5.30; 5.27; 5.33 Newtons*seconds/kg — p=0.100
N/A N=25 Comparative Outcomes Assessment of the C-Leg With a New Knee Prosthesis
Other and Unspecified Complications of Amputation Stump
Primary: 75 Meter Self Selected Walking Test — 65.1; 64.0; 54.0 seconds
N/A N=12 Reducing Asymmetry During Gait Using the TPAD (Tethered Pelvic Assist Device) for Stroke Patients
Stroke
Primary: Force Symmetry Ratio During Gait — 0.71; 0.83 ratio
N/A N=36 Evaluation of a Modified Running-specific Prosthetic Foot
Transtibial Amputation
Primary: Metabolic Oxygen Consumption (VO2), Participants With Unilateral Amputation — 1041.1; 1077.4; 1210.9; 1253.5 ml/min — p=.18
N/A N=13 C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
Lower Limb Amputation Above Knee (Injury)
Primary: Change in 6 Minute Gait Test — 380.4; 380.4; 35.9; 26.7 meters — p=0.01
N/A N=12 Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?
Amputation
Primary: Affected Leg Peak Propulsive Horizontal Ground Reaction Force — 0.151; 0.145; 0.166; 0.150 proportion of body weight
N/A N=16 Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking
Traumatic Amputation of Lower Extremity
Primary: Metabolic Cost of Transport — 4.76; 4.57; 4.68; 4.11 J/Nm
N/A N=5 Transfemoral Socket Design and Muscle Function
Amputation
Primary: Residual Limb Hip Muscle Peak Torque at Baseline — 25.6; 14.9; 25.6; 13.1 newton-meters / kg*meters
Phase 3 N=7 Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot
Transtibial Amputation
Primary: Metabolic Oxygen Consumption During Ambulation — 3.45; 3.13; 2.97 Watts per kilogram
N/A N=31 Physical Activity Behavior Change for Older Adults After Dysvascular Amputation
Amputation · Diabetes Mellitus, Type 2 · Peripheral Artery Disease
Primary: Retention Rate — 14; 13 Participants
N/A N=147 Self-management to Improve Function Following Amputation
Amputation, Limb Loss
Primary: Short Musculoskeletal Function Assessment (SMFA) — 32.34; 30.19 score on a scale
N/A N=23 Falls in Older Persons With Limb Loss
Amputation · Elderly
Primary: Foot's Height During the Swing Phase of Walking (i.e., Foot Clearance) Measured in Centimeter — 6.1; 5.5; 6.1; 5.7 cm
N/A N=11 Personalizing MPK Prescription
Transfemoral Amputation
Primary: Ten Meter Walking Test — 0.9963; 1.1051; 1.1111 Meters per second — p=0.126
Phase 3 N=10 Southern Bone & Joint Study - Brimless Sockets
Socket Designs of Transfemoral Amputees.
Primary: Gait
N/A N=31 Community Walking Trials: Comparing Prosthetic Feet
Lower Extremity Amputation
Primary: Difference Between Investigational Foot and Usual Foot in the Prosthetic Evaluation Questionnaire (PEQ): Ambulation Sub-Scale — 4.2 score on a scale — p=0.092
N/A N=6 No Power Bionic Lower Extremity Prosthesis
Amputation · Amputation, Traumatic · Amputation; Traumatic, Leg, Lower
Primary: Peak Propulsive Ground Reaction Force on the Prosthetic Side During Walking — .175; .166; .166 Body-weights