N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=88 An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma
Musculoskeletal Injury Trauma
Primary: Change From Baseline, at Weeks 2, 6 and 12 on the Patient Reported Outcome Measurement Information System (PROMIS) - Physical Function Between the Groups. — 18.65; 17.6…
N/A N=10 AMP30: Autologous Fat Grafting, Amputation Sites Pain: Randomized
Wounded Warrior · Limb Shortening · Amputation
Primary: Efficacy of Autologous Fat Transfer at Pain Modulation at Respective Amputation Sites — 1.3; 0 score on a scale
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=19 MRI Diffusion Tensor Tractography to Monitor Peripheral Nerve Recovery After Severe Crush or Cut/Repair Nerve Injury
Nerve Injury
Primary: Michigan Hand Questionnaire (MHQ) in TPNI Subjects Post Surgery — 33; 83; 5; 75 score on a scale
N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
N/A N=4,549 Longitudinal Study of Weight Change Following Lower Limb Amputation
Amputation Wound · Traumatic Amputation of Toe · Dysvascular Amputation of Lower Limb
Primary: % Weight Change From Baseline — 5.5; 0.9 % weight change
N/A N=20 Endovascular Repair for the Descending Thoracic Aorta
Aorta Thoracic; Traumatic Rupture
Primary: Number of Participants With Major Adverse Events — 0 number of serious adverse events
N/A N=3 Advanced Visuohaptic Surgical Planning for Trauma Surgery
Maxillofacial Injuries
Primary: Percentage of Deviation From Actual Surgical Outcome During Virtual Repair of Mandibular Fractures, Using the Novel Visuohaptic Computational Platform That Was Developed…
Phase 4 N=16 Pathophysiology of Post Amputation Pain
Amputation Stumps · Neuroma
Primary: Change in Pain — -0.3; -2; -1; 1.3 units on a scale
N/A N=51 Evaluation of the GORE Conformable TAG® for Treatment of Traumatic Transection
Thoracic Injuries
Primary: All Cause Mortality — 4 participants
Early Phase 1 N=33 N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes
Diabetes Mellitus · Critical Limb Ischemia · Lower Limb Amputation Knee
Primary: Change in Postoperative Laser-Assisted Fluorescent Angiography (LAFA) Perfusion. — 0.060; 0.096; 0.045; 0.031 percentage of defect
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
N/A N=147 Self-management to Improve Function Following Amputation
Amputation, Limb Loss
Primary: Short Musculoskeletal Function Assessment (SMFA) — 32.34; 30.19 score on a scale
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=180 Operative and Non-operative Treatment of Traumatic Arthrotomies
Traumatic Arthrotomy
Primary: Cost of Treatments — 1089; 11,973 USD
N/A N=121 Trauma Survivors Outcomes and Support Study IV
Posttraumatic Stress Disorder · Depression · Suicide
Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05
N/A N=38 Collaborative-care Rehabilitation After Dysvascular Amputation
Diabetes Complications · Peripheral Arterial Disease
Primary: Timed Up-and-Go Test — 19.4; 20.7; 18.2; 18.8 seconds — p=0.87
Phase 2 N=31 Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: A Pilot and Feasibility Study
Brain Injuries · Wounds and Injuries · Hemorrhage
Primary: Pediatric Quality of Life Inventory (PedsQL) — 64.9; 60.2; 67.2 Quality of life units * months
N/A N=20 Upper Limb Loss Perturbation Response
Amputation
Primary: Whole-body Angular Momentum in Sagittal-plane; Momentum of the Body in the Sagittal Plane of Walking Progression — 0.025; 0.031; 0.027; 0.028 Unitless (normalized)
N/A N=16 Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Traumatic Brain Injury · Stroke
Primary: Fugl-Meyer Assessment of Motor Recovery for Upper Limb (FMA) — 7.5 score on a scale
N/A N=9 Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
Infection Wound · Disruption of Nerve Repair
Primary: 2-point Discrimination Test — 7.5 mm
Phase 4 N=144 Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
Phantom Limb Pain
Primary: "Average" Phantom Limb Pain Intensity 4 Weeks Following Initiation of an Ambulatory Continuous Peripheral Nerve Block (as Measured by the Numeric Rating Scale Within the…
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 2 N=24 Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth
Periapical Diseases
Primary: Changes Between Initial and Post Treatment Dimensions of Periapical Lesions — 37.34; 34.04; 16.20; 17.54 square millimeters — p=<0.01
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=430 Trauma Medical Home for Older Injured Patients
Injuries
Primary: Change in Self Reported Physical Recovery — 40.42; 39.18 score on a scale