Clinical Trial Search

Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05

Primary: Change From Baseline, at Weeks 2, 6 and 12 on the Patient Reported Outcome Measurement Information System (PROMIS) - Physical Function Between the Groups. — 18.65; 17.6…

Primary: Participation Assessment With Recombined Tools - Objective 17 (PART-O-17) — 1.30; 1.33 units on a scale — p=0.44

Primary: Fraction of Time That Brain Oxygen Levels Are Below the Critical Threshold of 20 mm Hg . — 0.15; 0.44 Proportion

Primary: 4 Hour Mortality — 50; 32 Participants

Primary: The Feasibility of Inpatient Bedside Neurocognitive Testing of Pediatric Patients With Minor Traumatic Brain Injury. — 120 participants

Primary: Change in Post Traumatic Concerns Over the Course of the Six Months After Injury — 80; 83; 55; 59 Participants — p==0.01

Primary: Percent Change in Trail Making Test Part B Time to Completion — -25.6 percent change in time

Primary: Change in Self Reported Physical Recovery — 40.42; 39.18 score on a scale

Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).

Primary: Pediatric Quality of Life Inventory (PedsQL) — 64.9; 60.2; 67.2 Quality of life units * months

Primary: Michigan Hand Questionnaire (MHQ) in TPNI Subjects Post Surgery — 33; 83; 5; 75 score on a scale

Primary: Appropriate Use of Key Performance Indicators in Initial Assessment and Management of the Injured at Non-tertiary Hospitals in Ghana — 1807; 1894; 1194; 1787…

Primary: Number of Patients With 1 or More Emergency Department Visits Per Quarter — 225; 225; 90; 79 Participants

Primary: Percent Passing the Galveston Orientation Amnesia Test (GOAT) Within 28 Days Post Injury — 12; 14 Participants — p=0.99

Primary: Change From Baseline PTSD Checklist- Civilian (PCL-C) Over the Course of the Year After Injury — -1.65; 0.08; -4.02; -1.44 score on a scale

Primary: Number of Participants With Improved Cerebral Perfusion — 8 Participants

Primary: Number of Participants Who Reported 5 Themes — 6; 6; 6; 6 participants

Primary: Maximum Oxygen Uptake at Baseline. — 29.0 mL/kg/min

Primary: Change in Quality of Life as Measured by the Short Form-36 (SF-36) — 47.97 score on a scale

Primary: Number of Participants With Major Adverse Events — 0 number of serious adverse events

Primary: Duodenal-related Complications — 13; 11; 8; 19 percentage of subjects

Primary: Percentage of Participants With Worsening TBI Hemorrhage — 5.9; 3.6 percentage of participants

Primary: Cerebral Blood Flow Velocity in the Left (L) and Right (R) Middle Cerebral Artery (MCA), Internal Carotid Artery (ICA), and Basilar Artery (BA). — 3.2; 6.7; 4; 12.7 ml/sec

Primary: Responses From the TBI Clinical Reminder — 61; 88 percentage of participants

Primary: Number of Subjects Completing the Two Structured Outpatient Intervention Programs Resilience and Adjustment Intervention (RAI) vs. RAI With Follow-up Booster Sessions…

Primary: Change From Baseline in Fugl-Meyer Motor Scale (FMMS) Score at Week 24 Among All Patients — 6.0; 11.0; 8.1; 2.3 Change in score on a scale from baseline — p=0.0401

Primary: Test-retest Reliability SAFE-TBI — 0.372; 0.504; 0.581 kappa (reliability)

Primary: Receptor Binding (Vt) — 2.53; 2.21; 3.21; 3.22 mL/cm^3

Primary: Self-report — 7.79; 6.49; 7.61; 7.73 units on a scale