N/A N=300 Cefpodoxime vs Ciprofloxacin for Acute Cystitis
Urinary Tract Infection
Primary: Clinical Cure — 140; 123; 10; 27 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=139 Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Recurrent Urinary Tract Infection in Adult Women
Primary: To Evaluate the Effect of Oral Supplementation With Lactobacillus Reuteri on the Frequency of Confirmed UTI in Adult Women With Recurrent UTI. — 1.2; 1.3 Number of…
Phase 4 N=250 Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection (uUTI)
UTI - Lower Urinary Tract Infection · Antibiotic Resistant Infection
Primary: Number of Subjects With Combined Clinical and Microbiologic Response — 70 Participants
N/A N=300 Single Dose Monurol for Treatment of Acute Cystitis
Urinary Tract Infection
Primary: Number of Participants Who Were Cured — 120; 130 Participants — p=<0.001
Phase 4 N=35 A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department
Uncomplicated Bacterial Cystitis
Primary: Number of Participants With Clinical Cure at Day 7 — 13; 12 participants
Phase 3 N=1,671 Oral Sulopenem-etzadroxil/Probenecid Versus Ciprofloxacin for Uncomplicated Urinary Tract Infection in Adult Women
Uncomplicated Urinary Tract Infections
Primary: Percentage of Microbiologic Modified Intent to Treat Resistant (Micro-MITTR) Participants With Overall Success — 62.6; 36.0 percentage of participants
Phase 2 N=225 Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis
Uncomplicated Urinary Tract Infection · Cystitis
Primary: Number of Participants With an Investigator Assessment of Clinical Response at the Post Therapy Evaluation (PTE) Visit (ITT Population) — 48; 42; 46; 7 Participants
Phase 2 N=22 Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Infections, Bacterial
Primary: Area Under the Plasma Concentration-time Curve (AUC) From Zero (Pre-dose) Over the Dosing Interval (AUC[0-tau]) of Gepotidacin — 20236.2; 29313.8 Hours* nanogram per…
Phase 3 N=380 A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Urinary Tract Infections
Primary: Number of Participants With Therapeutic Response (TR) (Combined Per-participant Microbiological and Clinical Success) for Gepotidacin at the Test of Cure (TOC) Visit…
Phase 4 N=154 Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery
Pelvic Organ Prolapse
Primary: Number of Participants Experiencing Urinary Tract Infection Within 6 Weeks of Surgery — 13; 13 Participants — p=0.97
Phase 3 N=97 A Study in Adolescent and Adult Female Participants to Evaluate Clinical Symptom Improvement and the Safety of Gepotidacin During Treatment of Uncomplicated Urinary Tract Infections (Acute Cystitis)
Urinary Tract Infections
Primary: Percentage of Participants Achieving Clinical Symptom Improvement at 24 Hours (±4 Hours) — 54.4 Percentage of participants
Phase 1 N=140 Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections
Uncomplicated Urinary Tract Infections · Urinary Tract Infections
Primary: Number of Participants With Microbiological Response at the Test of Cure (ToC) Visit — 10; 10; 1; 18 Participants
Phase 4 N=164 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery
Catheter-Associated Urinary Tract Infection
Primary: UTI — 15; 14 Participants — p=0.84
Phase 3 N=1,531 A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)
Urinary Tract Infections
Primary: Number of Participants With Therapeutic Response (TR) (Combined Per Participant Clinical and Microbiological Response) at the Test-of-Cure (TOC) Visit - Micro-ITT NTF-S…
Phase 2 N=126 Effectiveness of Single Dose Fosfomycin and Single Dose Levofloxacin as Pre-urodynamic Antibiotic for UTI Prevention
Urological System Complication of Procedure · Urinary Tract Infections
Primary: The Main Outcome Measure Was the Incidence of Urinary Tract Infection (UTI) Post-urodynamic Study (UDS), Diagnosed Through Urinalysis Indicating Leukocyturia, Positive…
N/A N=110 Restricted Reporting for Positive Urine Cultures
Bacteriuria · Urinary Tract Infection
Primary: The Number of Patients Receiving Appropriate Treatment — 44; 29 Participants
N/A N=201 Short-course Methenamine Hippurate for Prevention of Post-operative UTI
Urinary Tract Infections · Catheter-Related Infections
Primary: Treatment of Clinically Suspected UTI - Using Intent to Treat Analysis — 13; 12 Participants
N/A N=272 Seven vs. 14 Days Treatment for Male Urinary Tract Infection
Urinary Tract Infections
Primary: Resolution of UTI Symptoms 14 Days After Completing Active Antimicrobial Therapy — 111; 122 Participants
Phase 4 N=242 Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection
Urinary Tract Infections
Primary: Urinary Tract Infection — 11; 12 UTI
Phase 3 N=614 Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis
Complicated Urinary Tract Infection · Acute Pyelonephritis · cUTI
Primary: Proportion of Patients Who Achieve Composite Clinical and Microbiological Success at TOC (Test of Cure Visit) in the Microbiological Modified Intent-to-Treat (m-MITT)…
N/A N=773 Clinical Utility of a PCR Compared to Culture and Sensitivity Testing for the Management of cUTI in Adults.
Urinary Tract Infection Complicated · Urinary Tract Infection (cUTI) · Urinary Tract Infection (Diagnosis)
Primary: Favorable Clinical Outcomes (FCl) — 170; 132 Participants
Phase 2 N=370 Gentamicin Intravesical Efficacy for Infection of Urinary Tract
Postoperative Urinary Tract Infection · Pelvic Organ Prolapse · Stress Urinary Incontinence
Primary: Post-operative Urinary Tract Infection — 19; 20 Participants
Phase 3 N=125 Safety and Efficacy of Canephron® N in the Management of Uncomplicated Urinary Tract Infections (uUTI)
Urinary Tract Infection
Primary: Incidence of Adverse Drug Reactions During 7-day Treatment of uUTI Symptoms With Canephron® N — 0 Adverse Drug Reactions
Phase 3 N=1,605 Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)
Urinary Tract Infections
Primary: Number of Participants With Therapeutic Response (TR) (Combined Per Participant Clinical and Microbiological Response) at the Test-of-Cure (TOC) Visit - Micro-ITT NTF-S…
Phase 2 N=225 Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis
Urinary Tract Infections · Acute Pyelonephritis
Primary: Number of Participants With Clinical and Microbiological Response — 45; 46; 35 Participants
Phase 2 N=61 Multifaceted Treatment of Catheter-related Urinary Tract Infection
Spinal Cord Injury · Neurogenic Bladder · Urinary Tract Infection
Primary: The Primary Efficacy Outcome of the Study is Response to Treatment Which Will be Assessed at the End of Therapy. Successful Response to Treatment is Defined as…
Phase 3 N=115 Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014)
Urinary Tract Infection (UTI) · Complicated Urinary Tract Infection · Pyelonephritis
Primary: Percentage of Participants With Microbiological Response of Eradication at Test of Cure (TOC) — 80.7 Percentage of participants
Phase 3 N=1,395 Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults
Complicated Urinary Tract Infections
Primary: Percentage of Participants With Overall Success — 301; 325 Participants
Phase 4 N=70 Randomized Trial of Culture Directed Versus Empiric Antibiotics for Urinary Tract Infections in Older Women
UTI
Primary: Eligible Subjects That Were Enrolled in the Study — 70 Participants
Phase 4 N=60 Management of Sub-Clinical Bacteriuria in Pregnancy
Cystitis · Cystitis;Puerperium · Pyelonephritis
Primary: Number of Participants Who Have Cystitis — 4; 4 Participants