N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
N/A N=20 Upper Limb Loss Perturbation Response
Amputation
Primary: Whole-body Angular Momentum in Sagittal-plane; Momentum of the Body in the Sagittal Plane of Walking Progression — 0.025; 0.031; 0.027; 0.028 Unitless (normalized)
N/A N=147 Self-management to Improve Function Following Amputation
Amputation, Limb Loss
Primary: Short Musculoskeletal Function Assessment (SMFA) — 32.34; 30.19 score on a scale
N/A N=16 Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Traumatic Brain Injury · Stroke
Primary: Fugl-Meyer Assessment of Motor Recovery for Upper Limb (FMA) — 7.5 score on a scale
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=88 An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma
Musculoskeletal Injury Trauma
Primary: Change From Baseline, at Weeks 2, 6 and 12 on the Patient Reported Outcome Measurement Information System (PROMIS) - Physical Function Between the Groups. — 18.65; 17.6…
N/A N=19 MRI Diffusion Tensor Tractography to Monitor Peripheral Nerve Recovery After Severe Crush or Cut/Repair Nerve Injury
Nerve Injury
Primary: Michigan Hand Questionnaire (MHQ) in TPNI Subjects Post Surgery — 33; 83; 5; 75 score on a scale
N/A N=4,549 Longitudinal Study of Weight Change Following Lower Limb Amputation
Amputation Wound · Traumatic Amputation of Toe · Dysvascular Amputation of Lower Limb
Primary: % Weight Change From Baseline — 5.5; 0.9 % weight change
N/A N=144 Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study
Post-Amputation Phantom Limb Pain
Primary: Change From Baseline in Average Daily Phantom Pain Intensity — 0.5; 0 score on a scale
Phase 4 N=144 Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
Phantom Limb Pain
Primary: "Average" Phantom Limb Pain Intensity 4 Weeks Following Initiation of an Ambulatory Continuous Peripheral Nerve Block (as Measured by the Numeric Rating Scale Within the…
N/A N=10 Biomechanical Assessment of Gait in Lower-Extremity-Amputees
Prosthesis User
Primary: Overall Asymmetry Index — 0.064; 0.352; 0.541; 1.481 unit-less index (0 = perfect symmetry)
N/A N=10 AMP30: Autologous Fat Grafting, Amputation Sites Pain: Randomized
Wounded Warrior · Limb Shortening · Amputation
Primary: Efficacy of Autologous Fat Transfer at Pain Modulation at Respective Amputation Sites — 1.3; 0 score on a scale
N/A N=44 Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program
Traumatic Amputation
Primary: Lower Extremity Muscle Strength- Extension — 24.5; 26.4; 27.6; 34.1 Kilograms — p=<0.05
N/A N=12 Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
Amputation, Surgical · Amputation, Traumatic · Phantom Limb Pain
Primary: Average Pain Intensity Change From Baseline 1 Month Post-intervention — 0; 0; 0 score on a scale
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=60 Is Univalving or Bivalving of Long Arm Casts for Forearm Fractures Necessary?
Fracture of Shaft of Radius and/or Ulna · Metaphyseal Fracture of Bone of Upper Limb · Fracture of Upper Limb, Level Unspecified
Primary: Complication Rate of the Cast Type — 9; 12; 8 participants
N/A N=4 Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Phantom Limb
Primary: Stimulation Thresholds to a Variety of Stimulus Parameters — 2.13 milliamps
N/A N=44 Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
Cerebral Palsy · Hemiplegia · Children
Primary: Change in Score on Assisting Hand Assessment (AHA) — 0.42; 0.56 score — p=<0.01
N/A N=10 Assessment of Limb Perfusion During Junctional Tourniquet
Bleeding
Primary: Muscle Perfusion — 0.32; 0.10 IU/s
Early Phase 1 N=33 N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes
Diabetes Mellitus · Critical Limb Ischemia · Lower Limb Amputation Knee
Primary: Change in Postoperative Laser-Assisted Fluorescent Angiography (LAFA) Perfusion. — 0.060; 0.096; 0.045; 0.031 percentage of defect
Phase 4 N=75 Unicirc vs Open Surgical Circumcision
Circumcision, Male
Primary: Time Elapsed From First Clamp (Surgical) or Start of Insertion of Bell (Unicirc) to Beginning of Wound Dressing — 12; 25 Minutes
N/A N=23 Falls in Older Persons With Limb Loss
Amputation · Elderly
Primary: Foot's Height During the Swing Phase of Walking (i.e., Foot Clearance) Measured in Centimeter — 6.1; 5.5; 6.1; 5.7 cm
N/A N=5 Neural Adaptation After Tendon Transfer and Training in Tetraplegia
Spinal Cord Injury
Primary: Pinch Force — 8.7; 10.6 newtons
N/A N=121 Trauma Survivors Outcomes and Support Study IV
Posttraumatic Stress Disorder · Depression · Suicide
Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05
N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
Phase 4 N=16 Pathophysiology of Post Amputation Pain
Amputation Stumps · Neuroma
Primary: Change in Pain — -0.3; -2; -1; 1.3 units on a scale
N/A N=1,051 Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2)
Hemorrhagic Shock · Traumatic Brain Injury
Primary: 4 Hour Mortality — 50; 32 Participants
N/A N=20 Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
Hearing Loss, Unilateral
Primary: Change Over Time in the Ability to Perceive Single Words as Assessed by Consonant-Nucleus-Consonant (CNC) Word Recognition Testing — 1.4; 14.4; 28.2; 45.0 percentage of…