30 closest matches · ranked by relevance
Spinal Fractures · Osteoporosis
Primary: Back-specific Functional Status Using Roland-Morris Disability Questionnaire (RDQ) Scale at 1 Month — 12.0; 13.0 units on a scale — p=0.49
Postmenopausal Osteoporosis
Primary: Proportion of Participants With New Vertebral Fractures — 28; 64 Participants (with at least one event) — p=0.000094
Vertebral Compression Fracture
Primary: Comparison of 3 Month ODI Score Between Unipedicular and Bipedicular Kyphoplasty Groups — 15; 14 units on a scale — p=0.85
Spinal Fractures · Fractures, Compression · Back Injuries
Primary: Proportion of Participants With Study Success — 120; 123 participants
Compression Fracture of Vertebral Body · Osteoporosis · Cancer
Primary: Back Pain Change From Baseline at 3 Months — 8.7; 2.7; -6.0 units on a scale
Cancer · Spinal Fractures
Primary: The Functional Status, as Measured by the Roland-Morris Disability Questionnaire (RDQ) at 1 Month — 17.6; 18.2; 9.1; 18.0 score on a scale
Osteoporosis · Vertebral Fracture
Primary: Time Used to Walk 20 m at Maximal Speed. — 14.9; 14.7; 13.4; 15.2 Seconds
Back Pain
Primary: Sum of Pain Intensity Difference Over 3 Days (SPID72) — 139.0; 129.4; 114.2 Scores on a scale
Metastatic Cancer · Pain · Unspecified Adult Solid Tumor, Protocol Specific
Primary: Pain Response as Measured by VAS at 3 Months — 8; 12; 1 Participants
Compression Fracture
Primary: Oswestry Disability Index (ODI) at 12 Weeks — 35.95; 33.54; 37.83 units on a scale
Osteoporosis
Primary: Incidence of New or Worsening Vertebral Fractures in Osteoporotic Subjects Treated With Denosumab Compared to Placebo — 3.6; 10.3; 7.2 Vertebral fractures — p=0.0001
LC Pelvic Fracture
Primary: Posttreatment Pain — 5.3; 6.2; 4.2; 5.6 scores on a scale
Spondylosis · Cervical Spondylosis · Spondylolisthesis
Primary: Fusion Rates Per Level Using the Bridwell Interbody Grading Scale — 64; 50 Fusions
Osteoporosis, Postmenopausal · Back Pain · Spinal Fracture
Primary: Number of Participants Responding With at Least a 30% Reduction in 24-Hour Worst Back Pain Severity at the 6-Month Endpoint — 206; 193; 142; 143 participants — p=0.642
Spinal Cord Injury · Bone Loss · Osteoporosis
Primary: Bone Mineral Density BMD of the Total Hip as Assessed by DXA. — 0.66; 0.63; 0.64; 0.65 g/cm^2 — p=0.84
Spinal Cord Injury
Primary: Change in Trabecular Plate Width (Tb.PW) for Femur and Tibia at 4.5 Months — 1785.42; 1819.41; 1805.52; 1834.67 μm
Osteoporotic Fractures · Spinal Fractures
Primary: Feasibility of Recruitment and Retention — 66; 64 Participants
Osteoporosis · Atypical Femoral Fracture
Primary: Radiologic Evidence of Bone Healing — 12.6; 11.2; 15.4; 13.2 units on a scale
Lumbar Spondylolisthesis · Degenerative Disc Disease · Degenerative Spondylolisthesis
Primary: Incidence of Successful Lumbar Fusion Measured Radiographically — 13; 11 Participants
Osteoporotic Fractures
Primary: Number of Participants With Evidence of Cortical Bridging for Fracture Healing — 9; 8 Participants
Proximal Humeral Fracture
Primary: Success Rate(Ability to Proceed With Surgery Without the Need for Intravenous Narcotics, General Anaesthesia, Rescue Blocks or Local Infiltration by the Surgeon) — 31…
Spinal Cord Injury
Primary: Change in Areal Bone Mineral Density at Hip — 0.92; -12.0; 1.19; -12.9 percentage change
Hip Fractures
Primary: Efficacy in Hip Fracture Patients Confirmed by DXA Scan. — 0; 4.75; 7.15; 9.08 PBO adjusted percent change — p=0.0032
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 87; 86 percentage of participants
Idiopathic Scoliosis
Primary: Incidence of Treatment-Emergent Adverse Events — 11; 7; 20; 0 Participants
Spinal Cord Injury · Acute Spinal Cord Injury · Bone Loss
Primary: Percent Change in Bone Mass Density (BMD) in the Hip — -2.21; -12.82 percent change in bone mass density — p=0.05
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 74; 93 Percentage of participants
Lumbar Spondylosis · Lumbar Spondylolisthesis · Adult Degenerative Lumbar Scoliosis
Primary: Quality of Spine Fusion, Measured by the Number of Participants With Complete Spine Fusion at 1 Year — 11; 6 Participants
Spinal Cord Injuries
Primary: Percent Change From Baseline in Volumetric Bone Mineral Density (vBMD) at 6-Months — -11; -5.7 Percent Change
Lumbar Spinal Stenosis
Primary: Pain as Measured by Visual Analog Scale (VAS). — 2.17 units on a scale — p=<0.0001