N/A N=828 Multiple Areas of Pain (MAP)
Chronic Pain
Primary: Multi-site Pain Index — 0.52 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=19 Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
Fibromyalgia · Chronic Pain · Depression
Primary: Gracely Box Intensity Rating Scale — 13.18; 14.43; 10.64; 13.00 units on a scale
N/A N=38 Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Chronic Pain · Chronic Lower Back Pain · Back Pain
Primary: Changes in Patient Reported Pain and Discomfort — 47; 13; -30; -18 percent change from baseline
N/A N=290 Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"
Chronic Pain · Pain · Widespread Chronic Pain
Primary: Brief Pain Inventory-Intensity (BPI-Intensity) — 6.19; 5.42; 5.68; 5.95 units on a scale — p=.165
N/A N=20 VANISH for Chronic Low Back Pain
Chronic Low-back Pain
Primary: Assessment of Opioid Use Via Subject Report — 47.5; 21.75 morphine milligram equivalent
Phase 4 N=86 Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
Chronic Pain
Primary: Pain Intensity — 11; 29 Participants
Phase 2 N=29 Low Dose Naltrexone for Chronic Pain From Arthritis
Osteoarthritis · Arthritis, Rheumatoid · Arthritis, Psoriatic
Primary: Brief Pain Inventory - Pain Interference — -23; -22 units on a scale — p=0.90
Phase 4 N=41 Milnacipran in the Treatment of Widespread, Non-Joint Pain in Rheumatoid Arthritis
Arthritis, Rheumatoid
Primary: Brief Pain Inventory (BPI) Change — 5.2; 5.6; 4.9; 4.8 units on a scale — p=0.42
N/A N=770 Strategies to Assist With Management of Pain
Chronic Low Back Pain
Primary: Composite Pain Severity — 5.6; 5.6 score on a scale
N/A N=100 Mechanisms of Sleep Disruption Hyperalgesia
Sleep Deprivation · Pain
Primary: Spinal Sensitization as Assessed by Area of Secondary Hyperalgesia (2HA) After Two Nights of Uninterrupted Sleep and Two Nights of 8 Forced Awakenings — 1276.25…
N/A N=37 Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans
Chronic Low Back Pain
Primary: Patient Reported Outcomes Measurement Information System Pain Intensity — 48.84 units on a scale — p=0.05
Early Phase 1 N=22 Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
Chronic Pain · Opiate Dependence · Lower Back Pain
Primary: Change in Quantitative Pain Testing Following Active TMS Compared to Baseline — 1.4; .3 Change from Baseline (degrees C) — p=.83
N/A N=51 Positive Psychology for Chronic Pain Self-management
Chronic Pain
Primary: Change in Pain Interference — -3.82; .32 T-score
N/A N=278 Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV
Chronic Pain
Primary: Brief Pain Inventory (BPI) Total Score — 4.74; 5.99; 5.13; 5.74 score on a scale
N/A N=525 Integrated Services for Pain: Interventions to Reduce Pain Effectively
Chronic Pain
Primary: Change From Baseline in Average Daily Opioid Dose in Morphine Milligram Equivalents (MME) at Month 12 — -11.6; -6.0 Morphine Milligram Equivalents (MME) — p=0.31
N/A N=779 Acupuncture Approaches for Chronic Pain
Chronic Pain · Osteoarthritis · Neck Pain
Primary: Pain Interference as Measured by the Brief Pain Inventory (BPI) (Intent to Treat Model) — 6.0; 6.1; 5.1; 4.8 Units on a Scale — p=0.0691
N/A N=764 Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans
Chronic Pain
Primary: Change in Pain Interference — 4.91; 5.49; 5.69 scores on a scale — p=.02
N/A N=217 An Evaluation of MBSR and CBT for Veterans With Chronic Pain
Chronic Pain · Pain
Primary: Pain Interference Subscale of Brief Pain Inventory (BPI) — 4.7; 4.8; 4.9; 4.4 score on a scale
Phase 3 N=250 Stepped Care to Optimize Pain Care Effectiveness
Pain
Primary: Brief Pain Inventory (Pain) — 3.57; 4.59 units on a scale
N/A N=57 Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial
Chronic Pain · Cognitive Impairment
Primary: Change in Pain Interference — -0.9; 0.2 units on a scale
N/A N=36 Improving Quality of Life for Adults Living With HIV and Chronic Pain
HIV Infections · Chronic Pain
Primary: Pain Intensity - Brief Pain Inventory — 7.3; 6.6; 6.1; 6.1 units on a scale
N/A N=401 Improving Chronic Pain Treatment in Primary Care
Pain · Chronic Disease · Depression
Primary: Adjusted Change in Pain-related Function (Roland Disability Score) — -1.4; -0.2 units on a scale
Phase 4 N=81 Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Chronic Low Back Pain · Degenerative Disc Disease · Depression
Primary: Percent Change in Average Daily Pain Score — 38.6; 30.0; 20.6 percent change — p=0.01
N/A N=36 Virtual Reality Guided Imagery for Chronic Pain
Complex Regional Pain Syndromes · Back Pain
Primary: Number of Participants Who Are Recruited But Not Enrolled as Documented in Participant Log — 60 Participants
N/A N=55 Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
Chronic Low Back Pain · Hip Ostearthritis · Myofascial Pain Syndrome
Primary: Participants' Level of Low Back Pain-associated Disability as Assessed by Roland Morris Disability Questionnaire (RMDQ) — -1.29; -0.08 score on a scale — p=<0.05
N/A N=44 Group-based Integrative Pain Management (IPMP+ Pilot)
Chronic Pain
Primary: Percentage of Eligible Patients Who Are Randomized — 44 Participants
N/A N=20 MEPS-Pain: Personalized Pain Self-management Planning by and for Veterans Pilot Study
Chronic Low Back Pain
Primary: Use of Tablet-based Application (App) for Creation of Pain Self-management Plan — 19 Participants
N/A N=73 A Behavioral Intervention for Depression and Chronic Pain in Primary Care
Chronic Pain · Depression
Primary: Change in Clinically Significant Depressive Symptoms, as Measured by the Montgomery Asberg Depression Rating Scale (MADRS) — 19.37; 20.87; 14.88; 18.67 score on a scale…
N/A N=184 Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functioning Among Veterans
Musculoskeletal Pain · Pain
Primary: Brief Pain Inventory -- Interference Subscale (BPI-I) to Assess 12 Week Follow-up — 4.58; 5.35 score on instrument — p=0.026
N/A N=23 4-week Mindfulness Program for Adults With Chronic Pain
Chronic Pain
Primary: Feasibility - Study Retention — 0.96 Proportion of participants