N/A N=99 A Study of Octave System for Improving Lines and Wrinkles of the Décolleté
Décolleté Wrinkles
Primary: Percentage of Treated Subjects With Improvement in Lines and Wrinkles of the Décolleté at Day 90 — 62.2 percentage of subjects
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=152 Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Percentage of Responders on Merz Aesthetic Scale (MAS) Décolleté Wrinkles - at Rest at Week 24 — 71.2; 6.3 percentage of subjects
N/A N=117 Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Responder Rate for Décolleté Wrinkles According to the Merz Aesthetics Scale (MAS)-At Rest Scale as Assessed by the Blinded Live Rater — 71.8; 83.7; 73.5 percentage of…
N/A N=30 An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
Wrinkles in Decolletage
Primary: Percentage of Responders on the Galderma Décolletage Scale (GDS), as Assessed Live by the Treating Investigator, at Month 9 — 93.8; 78.6 percentage of Participants
N/A N=125 Evaluation of the Ulthera System for the Treatment of the Decolletage
Chest Wrinkles
Primary: Percentage of Participants With a Reduction in Chest Wrinkles at 90 Days Post Treatment — 69.9; 15.9; 14.2 percentage of participants
N/A N=49 Prospective Pellevé™ Neck Wrinkle Study
Facial and Neck Rhytides
Primary: Change in Neck and Facial Wrinkles Using the Fitzpatrick Wrinkle Assessment — 74 percentage of participants
N/A N=25 Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Subject Satisfaction — 2.8 score on a scale
N/A N=35 Efficacy and Tolerability of SkinPen on Male and Female Subjects' Wrinkles of the Neck
Wrinkles
Primary: Assessment of Wrinkle Severity Using the Lemperle Wrinkle Assessment Scale — 3.31; 2.45 Score on a Scale — p=<0.01
Phase 3 N=42 Cryo-Touch II for the Treatment of Wrinkles
Facial Wrinkles
Primary: Number of Participants With Effectiveness and Safety Success — 30; 41 participants
N/A N=72 Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
Skin Aging
Primary: Change From Baseline in Ra (a dermaTOP Parameter), of Test Product Treated Versus (vs.) Untreated Side at Day 29 — -1.90; -0.12 Micro meter (µm) — p=0.0638
N/A N=15 Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Rhytides · Wrinkle
Primary: Change in Facial Wrinkles at 12 Weeks Post Final Treatment Compared to Baseline — -0.10 units on a scale
N/A N=68 Reducing Wrinkles Around the Eyes Using the Ulthera® System
Periorbital Wrinkles
Primary: Overall Improvement in Periorbital Wrinkles and Rhytids Around the Eyes — 47; 50 percentage of participants improved
N/A N=40 Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
Appearance of Facial Wrinkles
Primary: Fitzpatrick Wrinkle Assessment — 1.0; 1.5; 1.1 units on a scale, change in Fitzpatrick
Phase 4 N=34 Retinol on Human Skin Aging in East Asian Descent
Intrinsic Aging of Skin
Primary: Number of Genes Upregulated or Downregulated as Assessed by RNA Sequencing (Older Group, Retinol Versus Placebo) — 23; 21 genes
N/A N=20 Radio Frequency Microneedling for Suprapatellar Skin
Skin Laxity
Primary: Photographic Knee Laxity and Texture Evaluation — 1.87; 2.02 score on a scale
Phase 2 N=171 BOTOX® for the Treatment of Platysma Prominence
Platysma Prominence
Primary: Percentage of Participants With at Least 1-Grade Improvement at Day 14 as Rated by Investigator Using the Clinician Allergan Platysma Prominence Scale (C-APPS) — 12.0…
N/A N=51 TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides
Wrinkles · Rhytides
Primary: Changes to the Surface by Visual and Photographic Analysis. — 41 participants
N/A N=20 The Effects of Fractional CO2 Laser on Poikiloderma of Civatte
Poikiloderma of Civatte
Primary: Change in Overall Improvement of Poikiloderma of Civatte (POC) From Baseline at 12 Weeks — 11.01; 6.03; 8.51; 5.89 percentage
Phase 3 N=121 Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
Skin Aging
Primary: Treatment Success — 89.08 % of participants
N/A N=25 TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides
Wrinkles · Rhytides
Primary: Fitzpatrick Classification of Wrinkling and Degree of Elastosis. — 5.6; 5.56; 5.36; 5.32 Fitzpatrick Classification Scale
N/A N=50 Thermage CPT for Treatment of Facial and Neck Laxity
Skin Aging
Primary: Improvement in Laxity — 0.6; 1.0; 0.9; 1.3 units on a scale
Phase 4 N=30 Emervel for the Correction of Lower Face Wrinkles & Folds
Nasolabial Folds · Marionette Lines · Wrinkles
Primary: Number of Subjects With Naturalness of Expression in Motion (2D Video) — 30 Participants
N/A N=120 Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging
Skin Aging
Primary: Skin Aging Measured With the Photonumeric Scale. — 21.25; 21.36; 21.21; 21.03 Units on a scale
Phase 3 N=40 Light Emitting Diode (LED) for the Treatment of Wrinkles
Skin Aging · Photoaging of Skin
Primary: Percent Change From Baseline in Microtopographic Profilometry Ra Values (Skin Roughness). — 3.62; 18.57 Percent change post-treatment — p=<0.0001
N/A N=10 Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
Acne Scars - Mixed Atrophic and Hypertrophic · Wrinkle
Primary: Overall Wrinkle Improvement Assessed by the Fitzpatrick Wrinkle and Elastosis Scale (FWES) at 12 Weeks Post-Final Treatment — 5.97; 5.78 units on a scale
Phase 3 N=26 Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
Wrinkles
Primary: Posttreament Results of Chemical Peel if Botox A is Added as Pre-treatment — 1; 2 Units on a wrinkle severity scale — p=.002
N/A N=32 Lifting and Tightening of the Face and Neck Following an Increased Density Treatment
Skin Laxity
Primary: Improvement in Overall Lifting and Tightening of Skin — 48 percentage of participants improved
N/A N=20 Evaluation of the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
Wrinkles
Primary: Photographic Evaluation of Wrinkle Severity at Baseline — 5.7 score on a scale
N/A N=20 Evaluating the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
Wrinkles
Primary: Photographic Evaluation of Wrinkle Severity at Baseline — 5.25 score on a scale
N/A N=66 Reliability of the Facial Wrinkle Scale in Japanese Subjects
Facial Rhytides
Primary: Inter-rater Reliability of Assessment of Facial Lines Using the 4-Point Facial Wrinkle Scale (FWS-A) — 0.653; 0.637; 0.647; 0.654 Kappa statistics