Mode
Text Size
Log in / Sign up

ACIP Recommends JYNNEOS Vaccine for Adults at Risk During Mpox OutbreaksHealth Panel Recommends Mpox Vaccine for At-Risk Adults During Outbreaks

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Consider ACIP's 2023 JYNNEOS recommendation for adults at mpox outbreak risk.

This is a 2023 recommendation report from the Advisory Committee on Immunization Practices (ACIP). It addresses the use of the JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) vaccine for persons aged 18 years and older who are at risk for mpox during an mpox outbreak in the United States. The report describes the committee's recommendation but does not present new study results, primary outcomes, or a comparator group.

No specific efficacy or effectiveness data, such as vaccine efficacy estimates or case reduction numbers, are reported in this summary. The sample size, follow-up duration, and details of the population's specific risk factors are not provided.

Information on safety, tolerability, and adverse events is not reported. The report does not list specific limitations of the evidence considered by ACIP. As a formal recommendation, its practice relevance is to inform clinicians of the updated ACIP guidance for outbreak settings. Providers should consult the complete published recommendations for detailed indications, dosing schedules, and contraindications.

A U.S. health advisory committee, the Advisory Committee on Immunization Practices (ACIP), has released a 2023 recommendation for using the JYNNEOS vaccine. The guidance is for people aged 18 and older who are at risk of getting mpox during an outbreak. This is not a new research study but an official public health guideline based on a review of available evidence.

The report does not provide new data on how well the vaccine works or its safety in this specific situation. It does not describe the number of people involved or the specific outcomes that were reviewed to make this decision. The recommendation is meant to inform doctors and health departments.

Readers should understand this is a formal recommendation from experts, not a breaking news story about a new vaccine discovery. It confirms that health officials consider this vaccine an important tool for adults at risk during mpox outbreaks. The best step is to talk with a healthcare provider about personal risk and vaccine options if concerned about mpox.

What this means for you:
Health experts recommend the mpox vaccine for at-risk adults during outbreaks. Talk to your doctor about your personal risk.

Study Details

EvidenceLevel 5
PublishedJun 2025
View Original Abstract ↓
This report describes ACIP's 2023 recommendation for JYNNEOS vaccine use in people 18 years and older who are at risk for mpox during an mpox outbreak.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.