CDC releases 2025 adult immunization schedule for clinical practice

The Centers for Disease Control and Prevention (CDC) has released its 2025 immunization schedule for adults aged 19 years and older in the United States. This is a guideline and recommendation document intended to inform clinical practice, not a research study evaluating specific interventions or outcomes.

No study design, sample size, intervention details, comparator, or follow-up duration are reported, as this is not a clinical trial or observational study. The document does not present primary or secondary outcomes, effect sizes, or statistical measures. Safety and tolerability data for specific vaccines are not included in this schedule summary.

Key limitations include the absence of original research data and the fact that this is a practice guideline rather than evidence generation. The practice relevance is that this represents the CDC's official immunization recommendations for the coming year. Clinicians should refer to the complete schedule document for age-specific, condition-specific, and vaccine-specific guidance.