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Index testing increases HIV testing and diagnoses among contacts in 20 CDC-supported countriesWhen health workers test the contacts of HIV patients, do more people get diagnosed?

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Key Takeaway
Note: Observational data link index testing to more HIV tests and diagnoses in contacts, but evidence is descriptive.

An observational report from 20 CDC-supported countries examined the implementation of index testing for HIV among contacts of index patients from October 2016 to March 2018. The intervention involved scaling up HIV testing services for these contacts. The report found an increase in both the number of persons tested for HIV and the number who received a diagnosis of HIV infection. No absolute numbers, effect sizes, or statistical measures (p-values or confidence intervals) were reported for these increases. Safety and tolerability data were not reported. Key limitations include the observational design, lack of a control group, absence of statistical analysis, and unreported sample sizes. The timeframe was limited to 18 months. The practice relevance is restrained; this report describes an association between program scale-up and increased testing and diagnoses in specific settings. It does not establish causality or quantify the magnitude of benefit. Generalizability beyond these 20 CDC-supported countries is uncertain.

Finding people who have HIV but don't know it is one of the biggest challenges in stopping the virus. A report from 20 countries suggests a straightforward idea might help: when health workers test the partners and other contacts of someone newly diagnosed, more people end up getting tested. And importantly, more people who have HIV learn their status and can start treatment.

The report looked at a strategy called 'index testing' over about 18 months. It found that when this approach was scaled up, both the total number of people tested and the number of people diagnosed with HIV went up. This is a promising sign that focusing efforts on the people closest to someone with HIV can be an effective way to reach them.

However, this is an observational report, not a controlled study. It doesn't give us specific numbers—we don't know exactly how many more people were tested or diagnosed. It also didn't compare this approach to other ways of finding people with HIV. The work happened in 20 countries supported by the U.S. CDC, so we don't know if the results would look the same elsewhere. The takeaway is that the strategy shows potential, but we need more detailed research to understand its full impact.

What this means for you:
Testing the contacts of people with HIV may help find more undiagnosed infections.

Study Details

EvidenceLevel 5
PublishedMay 2019
View Original Abstract ↓
From October 2016 to March 2018, both the number of persons tested for human immunodeficiency virus (HIV) and the number who received a diagnosis of HIV infection using index testing increased in 20 CDC-supported countries.
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