Does having hidradenitis suppurativa increase the risk of pre-eclampsia or birth defects?
Hidradenitis suppurativa is a chronic skin condition that causes painful lumps and sores. Research shows that women with this condition face a higher chance of developing pre-eclampsia during pregnancy. However, studies have not found a significant increase in birth defects linked to this skin disease.
What the research says
A large meta-analysis of over 15 million pregnancies found that women with hidradenitis suppurativa have an 18% higher odds of developing pre-eclampsia compared to those without the condition 4. This same study also noted an increased risk for gestational diabetes and needing a caesarean section 4.
Another study looked at how inflammation and immune system changes during pregnancy can lead to complications like pre-eclampsia 2. While hidradenitis suppurativa involves chronic inflammation, the specific link to pre-eclampsia is supported by the statistical data showing higher odds ratios in affected women 45.
Regarding birth defects, the available research did not find a statistically significant association between maternal hidradenitis suppurativa and adverse fetal outcomes like birth defects 4. The study focused on outcomes such as preterm birth and caesarean sections but did not confirm an increased risk for structural birth defects 4.
What to ask your doctor
- How does my history of hidradenitis suppurativa change my risk for pre-eclampsia?
- What blood pressure monitoring schedule do you recommend for me during pregnancy?
- Are there specific skin treatments I should avoid while pregnant to protect my baby?
- What signs of pre-eclampsia should I watch for and report immediately?
This question is drawn from common patient questions about OB/GYN & Women's Health and answered using cited medical research. We do not provide individualized advice.