Researchers analyzed data from 1,316 patients with atrial fibrillation who underwent a procedure called percutaneous left atrial appendage occlusion (LAAO). This procedure is often used for patients at high risk of bleeding. The study specifically compared two different devices: the Watchman FLX and the Amplatzer Amulet.
The analysis found that the Amplatzer Amulet was associated with lower rates of stroke or transient ischemic attack (TIA) when compared to the Watchman FLX device. However, there were no significant differences found between the two devices regarding other safety measures, such as peridevice leaks, device-related thrombus, or pericardial effusion.
Because this is a meta-analysis based on pooled data from five studies, it shows an association rather than a direct cause. While the results suggest one device may have a lower risk of stroke, patients should discuss these specific findings with their doctors to determine which option is best for their individual health needs.
