A retrospective cohort study from a single surgical department examined 6 patients who developed delayed massive gastroduodenal artery (GDA) bleeding following gastrectomy or pancreaticoduodenectomy. The intervention studied was emergent angiographic arterial embolization. No comparator group was reported. The primary outcome was not specified.
Technical success of the emergent embolization procedure was achieved in all 6 patients (6/6). However, the number of interventions required for hemostasis varied: 3 patients achieved hemostasis after a single procedure, while 1 patient required two interventions, 1 required three, and 1 required four sequential interventions.
Regarding safety, acute liver function abnormalities were observed in 2 cases following embolization of the common hepatic artery. Serious adverse events, discontinuations, and tolerability were not reported. Key limitations include the retrospective design and very small sample size (n=6), which severely limits the strength of conclusions. Funding and conflicts of interest were not reported.
The authors describe the procedure as a rapid, minimally invasive, effective, and safe option for this critical condition. However, given the observational nature and limited data, this evidence can only suggest technical feasibility in a highly specific, critically ill population. It cannot establish effectiveness compared to other treatments, support generalization, or imply causality.
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Postoperative hemorrhage from the gastroduodenal artery (GDA) is a rare but life-threatening complication following upper gastrointestinal surgery. Its management is particularly challenging due to the frequent co-occurrence of hypovolemic shock, complex intra-abdominal infection, and malnutrition, which collectively contribute to high morbidity and mortality.
We conducted a retrospective analysis of patients who underwent either gastrectomy or pancreaticoduodenectomy and subsequently developed delayed massive GDA bleeding between January 2021 and June 2025 in the Department of General Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine.
Six patients was included in this study, of whom five had undergone radical D2 lymphadenectomy and developed duodenal stump leakage or anastomotic leakage and one had undergone pancreaticoduodenectomy. All cases experienced massive postoperative arterial hemorrhage. Emergent angiographic arterial embolization was successfully performed in all cases, achieving effective hemostasis with satisfactory outcomes. Specifically, one patient required four sequential interventions, one required three, one required two, and the remaining three achieved hemostasis after a single emergent procedure. Notably, acute liver function abnormalities were observed in two cases following embolization of the common hepatic artery.
Massive postoperative GDA hemorrhage is a life-threatening complication after abdominal surgery. Emergent arterial embolization proves to be a rapid, minimally invasive, effective, and safe therapeutic option for this critical condition.