Retrospective study identifies factors delaying blood pressure goal achievement after TEVAR for type B aortic dissection.
This retrospective cohort study analyzed 142 patients with type B aortic dissection who underwent thoracic endovascular aortic repair (TEVAR). The primary outcome was time to achieve early postoperative blood pressure (BP) goals. The median time to achieve BP goals was 9.5 hours, with an interquartile range of 6.0–13.8 hours.
Multivariate Cox regression analysis identified several factors independently associated with a slower rate of achieving BP goals. Advanced age was associated with a slower rate (HR = 0.97, P = 0.011). A history of hypertension was also associated with a slower rate (HR = 0.54, P = 0.005). Higher postoperative initial systolic BP (HR = 0.976, P = 0.003) and elevated postoperative pain scores (HR = 0.77, P = 0.002) were similarly associated with slower goal achievement.
Safety and tolerability data were not reported in this study. The key limitation is that the findings warrant prospective validation. The practice relevance is described as providing an evidence-based framework for optimizing postoperative management. The analysis does not establish causality, and the potential for improving patient prognosis should not be overstated.