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Retrospective study identifies factors delaying blood pressure goal achievement after TEVAR for type B aortic dissection.

Retrospective study identifies factors delaying blood pressure goal achievement after TEVAR for type…
Photo by Mufid Majnun / Unsplash
Key Takeaway
Consider that advanced age, hypertension, higher systolic BP, and pain may delay blood pressure goal achievement after TEVAR.

This retrospective cohort study analyzed 142 patients with type B aortic dissection who underwent thoracic endovascular aortic repair (TEVAR). The primary outcome was time to achieve early postoperative blood pressure (BP) goals. The median time to achieve BP goals was 9.5 hours, with an interquartile range of 6.0–13.8 hours.

Multivariate Cox regression analysis identified several factors independently associated with a slower rate of achieving BP goals. Advanced age was associated with a slower rate (HR = 0.97, P = 0.011). A history of hypertension was also associated with a slower rate (HR = 0.54, P = 0.005). Higher postoperative initial systolic BP (HR = 0.976, P = 0.003) and elevated postoperative pain scores (HR = 0.77, P = 0.002) were similarly associated with slower goal achievement.

Safety and tolerability data were not reported in this study. The key limitation is that the findings warrant prospective validation. The practice relevance is described as providing an evidence-based framework for optimizing postoperative management. The analysis does not establish causality, and the potential for improving patient prognosis should not be overstated.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
ObjectiveTo investigate the factors influencing the time to achieve early postoperative blood pressure (BP) goals in patients with type B aortic dissection (TBAD) following thoracic endovascular aortic repair (TEVAR) and to develop a refined nursing monitoring protocol.MethodsA retrospective cohort study was conducted, consecutively enrolling 142 TBAD patients who underwent TEVAR. Baseline patient characteristics, surgery-related indices, and postoperative indices were collected, with the primary observational endpoint being the time to achieve early postoperative BP goals. Univariate analysis and Cox regression analysis were employed to identify influencing factors. Based on the analytical results and combined with evidence-based practices, a refined nursing monitoring protocol was developed and refined using the Delphi expert consultation method.ResultsThe median time to achieve early postoperative BP goals among the 142 patients was 9.5 h (interquartile range: 6.0–13.8 h). Multivariate Cox regression analysis revealed that advanced age (HR = 0.97, P = 0.011), history of hypertension (HR = 0.54, P = 0.005), higher postoperative initial systolic BP (SBP) (HR = 0.976, P = 0.003), and elevated postoperative pain score (HR = 0.77, P = 0.002) were associated with a slower rate of achieving BP goals, thus identified as independent factors for prolonging the time to BP goal achievement.ConclusionAdvanced age, history of hypertension, higher postoperative initial SBP, and postoperative pain are independent factors prolonging the time to achieve BP goals in TBAD patients after TEVAR. The refined nursing monitoring protocol developed from these findings is targeted, systematic, and practical, providing an evidence-based framework for optimizing postoperative management, which holds potential for improving patient prognosis and warrants prospective validation.
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