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ALBI score predicts mortality risk in patients with non-ST-segment elevation myocardial infarction

ALBI score predicts mortality risk in patients with non-ST-segment elevation myocardial infarction
Photo by Joshua Chehov / Unsplash
Key Takeaway
Note that ALBI index is associated with increased mortality risk in NSTEMI patients (HR 5.07).

This retrospective cohort study included 982 patients diagnosed with non-ST-segment elevation myocardial infarction (NSTEMI). The primary exposure was the albumin-bilirubin (ALBI) score, assessed to determine its relationship with clinical outcomes following hospitalization. The study did not report a specific comparator group or intervention details beyond the exposure assessment.

The main result indicated that the ALBI index was associated with a hazard ratio of 5.07 for mortality after hospital discharge. The 95% confidence interval for this estimate ranged from 3.13 to 8.20. In terms of absolute numbers, 62 deaths occurred out of the 982 participants included in the analysis.

Safety data, tolerability, and adverse events were not reported in the provided evidence. The study design is a retrospective cohort study, which limits the ability to establish causality. Key limitations regarding follow-up duration and potential confounding factors were not reported. Consequently, the clinical relevance of the ALBI score for routine mortality prediction in NSTEMI patients requires cautious interpretation.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
ObjectiveThis study aims to evaluate the predictive value of the albumin-bilirubin (ALBI) score for mortality risk in patients with non-ST-segment elevation myocardial infarction (NSTEMI).MethodsA retrospective analysis was conducted on 982 patients with NSTEMI. A multivariate Cox proportional hazards model was established to analyze the predictive value of ALBI for mortality after hospital discharge in NSTEMI patients. Additionally, restricted cubic spline (RCS) plots were used to analyze the relationship between ALBI and post-discharge mortality. Operating characteristic (ROC) curves were generated to assess the predictive accuracy of ALBI, and nomograms were constructed to facilitate clinical application in predicting mortality after hospital discharge in patients with NSTEMI.ResultsAmong the 982 participants, 62 (6.3%) developed death during the follow-up. In unadjusted Cox regression models, the ALBI index had a hazard ratio (HR) of 5.07 (95% confidence interval CI: 3.13–8.20, P 
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